Associate Professor, Dept. of Neuroscience, @SCoBIRC, and @UKSBCoA @universityofky | passions = glia, TBI, aging, and Alzheimer's disease / ADRD
Lexington, Kentucky
Joined August 2019
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Check out this new mouse model that enables temporal tracking of IL-1β–expressing cells. After repetitive TBI, we identified a distinct subpopulation of microglia that upregulates IL-1β.
Paper link👉authors.elsevier.com/c/1m9sN…
Adam Bachstetter retweeted
📣 Student Spotlight 📣
Meet Savannah! Her goal is keeping the brains and pottery intact. 🧠🏺
#MDPhD #StudentSpotlight #UKMed #HandleWithCare #womeninstem
Adam Bachstetter retweeted
Congratulations to SBCoA Director, Linda Van Eldik, Ph.D.!
ALT Khalid Iqbal and Linda Van Eldik shown with Lifetime Achievement Award.
🏆 Linda Jo Van Eldik, Ph.D., is the 2026 recipient of the Khalid Iqbal Lifetime Achievement Award in Alzheimer’s Disease Research.
Dr. Van Eldik is the Director of the Sanders-Brown Center on Aging and the Alzheimer’s Disease Research Center, Co-Director of the Kentucky Neuroscience Institute, and Professor of Neuroscience at the University of Kentucky in Lexington, KY.
Her research focuses on dysregulated neuroinflammation, identifying potential points of intervention, and developing new small molecule drug candidates to slow progression of cognitive impairment and neurodegeneration. @UKSBCoA @UKYneuroscience
The OMB and the Politicization of Science | New England Journal of Medicine nejm.org/doi/full/10.1056/NE…
Adam Bachstetter retweeted
In other news, today the NIH proposed caping the maximum of grants at 2 per research lab, including collaborations.
grants.nih.gov/grants/guide/…
We're living in the upside down.
Lila Sciences may raise about $2 billion at an $8.5 billion valuation.
That number looks incredible if you treat Lila as a normal AI biotech. It makes a little more sense (maybe!) if you treat it as a bet on a new R&D operating system.
Lila’s pitch is AI Science Factories: AI systems connected to automated labs that generate hypotheses, design experiments, run them, learn from the results, and repeat. In other words: model, robot lab, experiment, data, repeat. The whole shebang.
Or “scientific superintelligence” and “operating system for science," as Lila calls it. (3/7)
We’re recruiting!
Tenure-track faculty position in traumatic brain injury (TBI) or spinal cord injury (SCI) research. Expertise in metabolism and mechanistic or translational aspects of neurotrauma are encouraged to apply.
Link to apply: ukjobs.uky.edu/postings/6095…
ALT A composite recruitment flyer for the University of Kentucky. The left side features a vintage anatomical drawing of a brain and spinal cord on a parchment background, with a podium displaying the SCoBIRC logo. Text reads "University of Kentucky Spinal Cord and Brain Injury Research Center" and "Apply Now." The top right shows a photo of a modern, clean laboratory corridor. The bottom right text reads: "The University of Kentucky’s Spinal Cord and Brain Injury Research Center (SCoBIRC) is hiring for a tenure-track faculty position in neurotrauma research, specifically TBI or SCI. We seek applicants at all ranks, including postdocs and early-stage investigators, focusing on areas like metabolism, inflammation, glia, neural repair, regeneration, chronic recovery, or post-traumatic epilepsy.
Adam Bachstetter retweeted
IL-1R1-positive dorsal raphe neurons drive self-imposed social withdrawal in sickness @CellCellPress cell.com/cell/fulltext/S0092…
Adam Bachstetter retweeted
Excited to share our new letter in Neuron!
We report that maternal inheritance of the 5xFAD (Tg7031) transgene suppresses both amyloid plaques and cerebral amyloid angiopathy.
doi.org/10.1016/j.neuron.202…
Adam Bachstetter retweeted
Rod-shaped microglia interact with neuronal dendrites to attenuate cortical excitability during TDP-43-related neurodegeneration: @ImmunityCP cell.com/immunity/fulltext/S…
Adam Bachstetter retweeted
A big thanks to the team @bu_cte and @joncherry86 for your support though this work and to @BachstetterLab and @Morganti_Lab for your article summarizing the paper which you can read here!
nature.com/articles/d41586-0…
Adam Bachstetter retweeted
Repeated head trauma causes neuron loss and inflammation in young athletes @Nature
nature.com/articles/s41586-0…
Adam Bachstetter retweeted
We are looking for new faculty members to join UF Biochemistry ! Come and expand your metabolism research with the largest spatial metabolomics facility in the country with 4 high-end MALDI imaging instruments and dedicated bioinformatic and AI support ! Apply below !
explore.jobs.ufl.edu/en-us/j…
Adam Bachstetter retweeted
Restoring movement to those with spinal cord injuries.
Spinal Cord and Brain Injury Research Center (SCoBIRC) director John Gensel helps treat Kentuckians with spinal cord injuries. Learn how @NIH funding is vital to that work. @UKYMedicine
Learn more: research.uky.edu/news/resear…
Congratulations to @LJohnsonLab on his excellent talk at the CSHL Neurodegenerative Disease conference on his ApoE switch mice. In my (biased) opinion, it sparked some of the most interesting questions of the meeting! Exciting work pushing the field forward.
@UKSBCoA @ResearchKY
Adam Bachstetter retweeted
Tenure-track faculty openings @universityofky, @SCoBIRC in mechanistic and translational neurotrauma research for traumatic brain injury or spinal cord injury.
ukjobs.uky.edu/postings/5134…
ukjobs.uky.edu/postings/5134…
@J_Neurotrauma @Neurotrauma @SfNtweets @ENONeurotrauma @IOSCIRS
Adam Bachstetter retweeted
Bachstetter et al. report lower Th17 cytokines from stimulated T cells in women with early cognitive decline, indicating a dementia-related immune shift linked to CD4+/CD8+ T cells, GFAP, and NfL levels. @BachstetterLab @scientistbarb @NIHAging @UKSBCoA tinyurl.com/33a2v78w
Adam Bachstetter retweeted
Spots are still available for our inaugural class! For more information and to apply visit: medicine.uky.edu/departments…
@UKYNeuro @scobirc @bellarmineU @bereacollege @CentreC @WVStateU @Transy @eku @wku @KyStateU @SCKY_1879