Physician Scientist, Nephrologist. Interests: #AKI, #Uromodulin, Multiplex imaging & Spatial analytics, Immune mediated kidney injury. Investigator @KPMProject
Indiana, USA
Joined May 2017
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Tarek M. Ashkar (El-Achkar) retweeted
Kidney casts contain high levels of PROM1, a marker linked to cell damage and dedifferentiation based upon new #ASNCJASN study. kidney.pub/CJASN0982
Tarek M. Ashkar (El-Achkar) retweeted
Kidney cells can protect themselves during injury, but the mechanisms were unclear.
ASCI member Tarek M. El-Achkar @AshkarLab & team @IUMedSchool now show that oxidative stress induces an isoform of uromodulin that re-routes to the mitochondria to enhance energy production.
View paper: jci.org/articles/view/183343
Tarek M. Ashkar (El-Achkar) retweeted
From the 3D micro-environment of the kidney to 4D atlasing of human organs, explore how cutting-edge imaging & spatial technologies are transforming #biomedicalresearch. Join @AshkarLab & @sarahteichmann1 at this live event! fcld.ly/hyh0vuq #CellMapCrew #HumanCellAtlas
Tarek M. Ashkar (El-Achkar) retweeted
Urine for a renal treat today & we're not being irrational! It is #worldkidneyday2025 & #PiDay, so it's time for a slice of kidney pi(e))! This CODEX image of a kidney pi slice was made by #hubmap researchers Drs. Tarek Ashkar & Sanjay Jain @wustl, no kidney-ing around!
ALT CODEX Image of a Kidney Pi Slice Red - podocytes, green - endothelial cells, yellow - smooth muscle cels and arterioles, cyan - thick ascending limb tubules, blue - proximal tubules, brown - distal convoluted tubules
Tarek M. Ashkar (El-Achkar) retweeted
An exciting new paper showing elevated uric acid in severe malaria predicts short- and long-term mortality and cognitive deficits in survivors. Potential new biomarker and pathway for intervention.
nature.com/articles/s41591-0…
Tarek M. Ashkar (El-Achkar) retweeted
I’m thrilled to share my first-author paper has been selected for APSselect @APSPublications @AJPRenal
“Acute kidney injury results in long-term alterations of kidney lymphatics in mice”: doi.org/10.1152/ajprenal.001…
Thank you to the incredible team that helped make this possible!
Tarek M. Ashkar (El-Achkar) retweeted
Sex, Acute Kidney Injury, and Age: A Prospective Cohort Study
bit.ly/4eTTMMj
@GolestanehLadan @basalely @AshkarLab @Linkermann_Lab @YaleNephrology @MonteNephrology #AKI #VisualAbstract
Tarek M. Ashkar (El-Achkar) retweeted
📢New ASN Guidance: Managing Obesity in Kidney Diseases.
Equip your practice with the latest strategies and evidence-based approaches for tackling obesity in patients with kidney diseases. 📑💡
Learn more: 🔗 jasn.org/KHGObesity
#Nephrology #KidneyCare #ObesityManagement
Tarek M. Ashkar (El-Achkar) retweeted
Fascinating @MayoClinicNeph Grand Rounds this morning with Dr. Tarek Ashkar @AshkarLab @IUKidney on the biology and physiology of uromodulin. The interface between nephrology and urology is ideal for studying the diverse regulatory roles of uromodulin as a stone inhibitor.
Tarek M. Ashkar (El-Achkar) retweeted
DYK that not only is today #WorldPiDay, it is also #WorldKidneyDay2024 ! In honor of both days, here is a #CODEX image of a slice of kidney (pi) made by well-rounded #hubmap researcher Drs. Tarek Ashkar and Sanjay Jain @WUST. It's downright nephron-tastic!
ALT CODEX Kidney image
Tarek M. Ashkar (El-Achkar) retweeted
Attention Authors: There's a new way to send presubmission inquires to the @ASNKidney Journals!
Authors may now submit inquiries about journal interest in a manuscript prior to submission at forms.gle/bVCugDMeoXK6BAo77
ALT ASN Journals logos
Tarek M. Ashkar (El-Achkar) retweeted
The @ASNKidney Journal Portfolio board, including the Editors-in-Chiefs and Deputy Editors of JASN, @CJASN, and @ASNKidney360, met today to collaborate on the future direction of the Journal Portfolio
Tarek M. Ashkar (El-Achkar) retweeted
Here's our gift to you
HuBMAP Holiday Haiku
Our yearly review
HuBMAP researchers
Show where molecules are with
CODEX images
Urine good hands
With Drs. Askhar and Jain
They keep it renal
Antibodies stain
Cell structures in the kidney
I kid-ney you not
Does your stream of consciousness ever lead you to wonder what the kidney beans to you? Then check out this #CODEX image, part of the urgent work done by @IU's Dr. Tarek Ashkar and @WUSTL's Dr. Sanjay Jain. Urine in for a treat, and we aren’t kidney-ing! @_hubmap @kpmproject
ALT CODEX image of kidney
Tarek M. Ashkar (El-Achkar) retweeted
CJASN is pleased to announce the incoming Editorial Team, under the direction of EIC @ConnieMRhee, effective January 1, 2024
@sagarnigs @kamkalantar @KatherineTuttl8 @ChrisChanUHN @keepingitrenal @J_B_Kendrick @LaetitiaKoppe @MBaliker @gratefull080504
ALT Incoming CJASN Editorial Team
Tarek M. Ashkar (El-Achkar) retweeted
JASN is pleased to announce the incoming Editorial Team, under the direction of EIC @rajmehrotra1122, effective January 1, 2024 bit.ly/JASNEditors
@MagdalenaMadero @girish_nadkarni @SannaCherchiLab @Sheena_Singh15 @sydney_tang @edgarvlermamd @Nephro_Sparks
ALT Incoming JASN Editorial Team
Tarek M. Ashkar (El-Achkar) retweeted
📢 We are excited to share our new perspective, "Precision Medicine in Nephrology: An Integrative Framework of Multidimensional Data in the Kidney Precision Medicine Project", published in the American Journal of Kidney Diseases.
Read and share here: sciencedirect.com/science/ar…
Tarek M. Ashkar (El-Achkar) retweeted
In the past decade, both the urinary and serum forms have gained attention as potential biomarkers for kidney function. This study found that serum uromodulin levels are higher in healthy female participants than healthy male participants bit.ly/KID0197
@AshkarLab
ALT Serum uromodulin is increased in healthy female participants. (A) Distribution of serum uromodulin levels for female (red) and male (blue) participants. (B) Serum uromodulin levels are higher in female than male participants. (C) Serum uromodulin levels indexed to eGFR are higher in female than male participants. (D) Serum uromodulin is stable with age in male participants. R2=8.44×10−5, P = 0.9394, F=0.005827. (E) There is a trend toward decreasing serum uromodulin with age in female participants. R2=0.01228, P = 0.0528, F=3.779.
Tarek M. Ashkar (El-Achkar) retweeted
CJASN is pleased to announce that @ConnieMRhee, MD, MSc, has been appointed Editor-in-Chief. She will begin her term on January 1, 2024. Dr. Rhee is currently a member of the CJASN Editorial Board and is the first female CJASN Editor-in-Chief. Learn more: bit.ly/3Z5Zio8
ALT Join ASN in welcoming the new Editor-in-Chief of the Clinical Journal of the American Society of Nephrology: Connie Rhee, MD, MSc
Tarek M. Ashkar (El-Achkar) retweeted
In this @NatureComms article, HuBMAP researchers define the spatial molecular landscape and specific pathways contributing to stone-mediated injury in the human renal papilla and identify associated urinary biomarkers:
nature.com/articles/s41467-0…
Tarek M. Ashkar (El-Achkar) retweeted
Faculty position @USF_HKRC @USFHealth with a focus on hypertension and renal physiology. Great place for work-life ⏰🏖️ 😜balance! Please RT!
Assistant/Associate/Full Professor (HKRC) jobs.sciencecareers.org/job/…
