@AnggonoLab

Our lab is interested in understanding the molecular basis of neuronal communication and synaptic plasticity during learning, memory and disease | @QldBrainInst

 Brisbane, Queensland
anggonolab.org
Joined October 2016
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  • Followers804
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📣 PhD Opportunity in Mathematical Modelling at The University of Queensland @UQ_News
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We are grateful to our wonderful collaborators @bertylee_ (@Macquarie_Uni), Mihwa Lee (@latrobe & @UniMelb), @PraneshPadmana1 (@UQ_News: SBMS & @QldBrainInst) and Mathew Jones (@UQ_News: SCMB) and all co-authors: Anson Tan, Lingrui Zhang, He Huang, Sooraj Das & Flora Cheng.
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Online now in @NatureComms nature.com/articles/s41467-0… We identify FTO as an endogenous negative regulator of PARP1 and the DNA damage response in cells beyond its role as an RNA demethylase. Thanks to Tianyi Zhu and @Joce_m6A, who led this project.

FTO suppresses DNA repair by inhibiting PARP1

Nature Communications - Maintaining genomic integrity is essential for the survival of organisms. Here, the authors identify FTO as an endogenous negative regulator of PARP1 and the DNA damage...

nature.com
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Interested in complex systems, brain evo-devo, and/or computational approaches to big questions in neuroscience? Check out new opportunities in our lab! 🧠🧬💻🦘🔬🏝️🏄‍♀️😍 Further details and deadlines will be announced soon! #PhD #Postdoc #NeuroJobs
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Replying to @Guyiguyi
Congrats Yi and the team!
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Replying to @Ih_current @Nature @thainmueller
Congrats Ingie, Rick and team! Beautiful work!
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Replying to @SamStehbens @robertr33 @arc_gov_au @drDJVDavid @NatureCellBio
Congrats Sam and team!
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Replying to @JasonSynaptic @UUtah @UUNeurobiology
Congrats Jason 🍻
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Replying to @deepak_iisc
Congratulations Deepak on the well-deserved fellowship! 🎉🍾 – at Brisbane, Queensland
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Replying to @LauraRoseFenlon @AusNeuroSoc
Congratulations Laura! 🍾 – at Brisbane, Queensland
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Team QBI is absolutely killing it today at the @AusNeuroSoc conference! Well done to Dr Dragan Rangelov, Dr Anson Tan, Rebekah Parkinson, and Dr Zengmin Li on your brilliant presentations amongst others...💜 #UQ #QBI #ANS2023 @neuronomist @DehorterLab @AnggonoLab
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Well done @an5on_jz from our lab and @BelalShohayeb from the Cooper lab for giving brilliant presentations at the #FAOBMB 2023 conference in Bangkok. Congratulations on your travel fellowships! @QldBrainInst @UQ_News @ITSASBMB – at Bangkok, Thailand
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Join us in Melbourne for Biomolecular Horizons 2024 22-26 September 2024. Visit the website to view the outstanding array of invited speakers and register now to take advantage of valuable savings! bmh2024.com/registration-ove…
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Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis dlvr.it/Sz7rGp

Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis

Tan and Jang et al. identify an interaction between the GluA1 subunit of AMPA receptors with the neuron-specific C2 domain-containing protein Copine-6 that is enriched in the somatodendritic compar...

cell.com
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Superb and very important study!! As we previous found, calcium sensors are important for the receptor trafficking (AMPAR-endocytosis) and synaptic plasticity. This study illustrated Copine-6 has an important role of AMPAR-exocytosis and lead to LTP.👏👍
Anggono Lab@AnggonoLab18 Nov 2023
Our study that shows the neuron-specific Copine-6 as a calcium sensor for activity-induced AMPA receptor exocytosis is now out in @CellReports. doi.org/10.1016/j.celrep.202…. Congrats to Anson @an5on_jz and Joanne @JoanneJangSE on your paper!
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We are glad to be part of a new study by Mihwa Lee, @CharlieBondXray, and @AFox_Perth on the differential contribution of low-complexity regions of SFPQ in biomolecular condensate formation, just published in @JMolBiol. Congrats @acmarshallphd! doi.org/10.1016/j.jmb.2023.1….
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Thanks to our wonderful collaborators @brettcollins100 and @MINTUCHANDRA4, and everyone in the @AnggonoLab who are involved in this study @Nish_Bhembre @batallas_ana @MitchellRinguet @NaYoNanodia @Joce_m6A and Huimin Guo. @UQ_News @QldBrainInst #CJCADR
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Our study that shows the neuron-specific Copine-6 as a calcium sensor for activity-induced AMPA receptor exocytosis is now out in @CellReports. doi.org/10.1016/j.celrep.202…. Congrats to Anson @an5on_jz and Joanne @JoanneJangSE on your paper!
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Replying to @yuning_hong @arc_gov_au @WDFCodes @LabGanley @SABE_latrobe @LTUresearchers @RACInational @LIMSLTU
Congrats @yuning_hong 👍
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#JNeurosci: Guntupalli, Park, Han et al. @AnggonoLab @QldBrainInst @UQ_News found that preventing degradation of AMPA receptors leads to an altered threshold for synaptic plasticity accompanied by short-term memory & cognitive flexibility deficits in mice. jneurosci.org/lookup/DOI/10.…
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