#single cell & spatial genomics | #Glioblastoma | #TumorHeterogeneity | #Tumorplasticity | #Tumormicroenvironment @MILOLab2 I am not a quitter...
Erlangen
Joined June 2009
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Our work is finally published in @GenomeMedicine Thanks to @AnGolebiewska, #Alessandro and all co-authors for your guidance, contributions and support. Thanks to the #reviewers for the thoughtful comments that significantly improved the manuscript.
I am super excited to share my PhD work where we characterized #TME in #GBM patient-derived orthotopic xenografts (#PDOXs), patient samples and GL261 mouse model🐁 using #scRNA-seq, spatial transcriptomics, multicolor FACS and functional assays: doi.org/10.1101/2023.03.05.5… 🧵 1/9
Yahaya Yabo, DVM, PhD retweeted
Happy to be part of this beautiful work! Congratulations to everyone involved.
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Yahaya Yabo, DVM, PhD retweeted
Ever wondered what makes brain tumors tick?
Excited by the breakthroughs in spatial transcriptomics and single-cell analysis? Find cancer neuroscience exciting?
Follow @MILOLab2 account on Instagram: cutting-edge insights, updates, and engaging content!
instagram.com/the_milolab?ig…
Truly inspiring talk by Crystal Mackall on their journey in treating brain tumors with #CARTcells. #SNO2024
Amazing talk by @MILOLab2 on using #spatialtranscriptomics data to model glioblastoma evolution #SNO2024
Yahaya Yabo, DVM, PhD retweeted
Very exciting new data and tools from @MILOLab2 presented at #eano2024 @EANOassociation
Excited to talk about our work on the role of myeloid cells in driving immunosuppression during CART cells therapy in #Glioblastoma. Thanks to @EANOassociation for the travel award. #EANO2024
#EANO2024 Congratulations to Yahaya Yabo for receiving the #EANO Travel Scholarship. Join him at his Oral Session: Myeloid cells drive immunosuppression of Chimeric Antigen Receptor T cells […]
📅 SUN, Oct 20 🕙 10:00-10:10 📍Alsh
#NeuroOncology #Glioblastoma
Yahaya Yabo, DVM, PhD retweeted
Has anybody mentioned the retreat? Cheers to an amazing year at @UniFAU, to fantastic science and to great new connections!
@MILOLab2 @yahayayabo @pkarschnia @ni_teske
Yahaya Yabo, DVM, PhD retweeted
💡Next up is Dieter Henrik Heiland talking about spatially resolved multi-omics and its clinical applications through advanced #MachineLearning.
#CRUKBrain24 | @MILOLab2 | @FAU_Germany | (AB)
ALT Dieter Henrik Heiland speaking at our Brain Tumour Conference
Yahaya Yabo, DVM, PhD retweeted
I'm thrilled to announce that our latest study, led by the incredible @BerendSnijder and Sohyon Lee, has been published in @NatureMedicine. It has been an amazing journey and it paves the way for many future explorations
nature.com/articles/s41591-0…
Yahaya Yabo, DVM, PhD retweeted
New in @NatureComms: Our labs new Gradient Screening algorithm and the Heart Project of my Twitterless Colleague Jan Kückelhaus advances #SpatialTranscriptomics analysis. Key advances:
1️⃣ Detects continuous expression gradients without clustering
2️⃣ Integrates histology & gene expression
3️⃣ Outperforms traditional DEA in complex tissues
4️⃣ Reveals hypoxia-immune spatial dynamics in #GBM
Explore #SPATA2: #CompBio
nature.com/articles/s41467-0…
Yahaya Yabo, DVM, PhD retweeted
Paper 🚨! Ecstatic, proud, grateful …Years of dedication from the whole lab, with the exceptional @djkloosterman and the one of a kind #JohannaErbani at its helm. What a journey all the way to @CellCellPress! How did it start (& end)? A 🧵1/n
cell.com/cell/fulltext/S0092…
Yahaya Yabo, DVM, PhD retweeted
Excited to share our new paper out in @NatureMedicine on tumor reactive T cells assembling in the proximal cranial bone of patients with glioblastoma.
A tremendous team effort with a lot of excellent cooperation partners!
Check it out now!
nature.com/articles/s41591-0…
Yahaya Yabo, DVM, PhD retweeted
Today is #GlioblastomaDay2024, designed to raise awareness of #glioblastoma, the most common primary brain cancer. At EANO, we are dedicated to advancing scientific research, improving diagnostic tools, & developing innovative therapies to combat this challenging disease. #GBMDay
Yahaya Yabo, DVM, PhD retweeted
Dieter Henrik Heiland will be going us at #CRUKBrain24 to discuss his working that bridges multi-omics & high-dimensional biological data with clinical applications through #AI. Secure your seat to hear from Dieter: bit.ly/3NvIcLK [3/4]
@MILOLab2 | @UniFAU
ALT Dieter Henrik Heiland Wellcome Sanger Institute Speaker, Spatial transcriptomics Image of Dieter on the right hand side
First paper alert 🚨 @MILOLab2
Happy to share our essay where we summarised how single cell transcriptomics helped in advancing our understanding of #glioblastoma.
We also outlined how these technologies have the potential to aid the transition to personalized care for patients.
#Glioblastoma is an intrinsically heterogeneous #cancer. @yahayayabo & @MILOLab2 advocate studying glioblastoma at a single-cell level to understand this heterogeneity, in the hope of guiding development of personalized & effective therapies #PLOSBiology plos.io/3VkJU75
Yahaya Yabo, DVM, PhD retweeted
Excited to finally see this work come out online @NaturePortfolio. In this work we identify FOXO1 overexpression as a strategy to improve CAR T cell persistence and metabolic function using CAR T derived from mice, healthy donors and cancer patients.
nature.com/articles/s41586-0…
