si queréis saber más, no dudéis en visitar nuestro artículo!!
if you want to dig deeper into what we did, check it out here!!
rdcu.be/eJHnn
🔴Investigadores del BSC usan #GemelosDigitales para explicar y predecir combinaciones de fármacos➕eficaces contra el #cáncer
💊Han identificado combinaciones de fármacos que bloquean el crecimiento del tumor de forma➕efectiva que los tratamientos por separado.
💻Este modelo, basado en simulaciones virtuales de tumores gástricos, representa una poderosa herramienta para guiar el diseño de terapias que exploten las debilidades metabólicas del cáncer.
➡ bsc.es/4Zv
Xavier Benedicto retweeted
🔴Investigadores del BSC usan #GemelosDigitales para explicar y predecir combinaciones de fármacos➕eficaces contra el #cáncer
💊Han identificado combinaciones de fármacos que bloquean el crecimiento del tumor de forma➕efectiva que los tratamientos por separado.
💻Este modelo, basado en simulaciones virtuales de tumores gástricos, representa una poderosa herramienta para guiar el diseño de terapias que exploten las debilidades metabólicas del cáncer.
➡ bsc.es/4Zv
Xavier Benedicto retweeted
🚨 New in PNAS!
🧬 64% of disease co-occurrences can be explained by transcriptomic similarities.
Comorbidities aren’t random—they have a molecular basis.
Here’s how we found it 👇 (1/n)
🔗 doi.org/10.1073/pnas.2421060… @PNASNews
@Alfons_Valencia
Xavier Benedicto retweeted
Amazing all what @xavierbemo has done for his master thesis. Quite amazing work. Cell level modelling able to predict (predict!) drug synergies from single drug data.
🚀 We are excited to share our newest work using constraint-based modelling & RNAseq to uncover how kinase inhibitors rewire metabolism in gastric cancer cells!
👉 biorxiv.org/content/10.1101/…
🧵 Let's dive deeper, shall we? 1/n
@miguep11 @asmundflobak @Alfons_Valencia @BSC_CNS
Xavier Benedicto retweeted
Thrilled to release MTEApy, a command line tool to perform model-based metabolic pathways enrichment analysis. We've currently implemented TIDE and CellFie algorithms. Comments and suggestions are welcome!
Last but not least, we bundled the TIDE and TIDE-e frameworks into a python library to perform Metabolic Task Enrichment Analysis (MTEApy), available in our Github! Feel free to check it out ;) and to reach us if you want to discuss anything!
👉 github.com/bsc-life/mteapy/
🧵 9/n
🚀 We are excited to share our newest work using constraint-based modelling & RNAseq to uncover how kinase inhibitors rewire metabolism in gastric cancer cells!
👉 biorxiv.org/content/10.1101/…
🧵 Let's dive deeper, shall we? 1/n
@miguep11 @asmundflobak @Alfons_Valencia @BSC_CNS
Last but not least, we bundled the TIDE and TIDE-e frameworks into a python library to perform Metabolic Task Enrichment Analysis (MTEApy), available in our Github! Feel free to check it out ;) and to reach us if you want to discuss anything!
👉 github.com/bsc-life/mteapy/
🧵 9/n
Xavier Benedicto retweeted
🎉 Thrilled to present our new work using constraint-based metabolic modelling & transcriptomics to uncover how kinase inhibitors rewire metabolism in gastric cancer cells.
Read more 👉 biorxiv.org/content/10.1101/…
#SystemsBiology #CancerResearch
@Alfons_Valencia @BSC_CNS