@CRC_CRC (Tier 2) in Spatial organization of living systems 💧🦠🪱🔬 (she/her)
Montréal, Québec
Joined December 2017
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🚨We're hiring!!🚨
The Biology Department @mcgillu is looking for a Quantitative Cell Biologist to join our diverse and interdisciplinary community.
Please share this ad broadly, and reach out if you have any questions.
mcgill.wd3.myworkdayjobs.com…
Check out our Roadmap for Condensates in Cell Biology 💧 🧫, which summarizes the stimulating discussions we had at @KITP_UCSB last summer! 🤓🌴
Big thanks to @ZwickerGroup for leading this effort!
journals.aps.org/prxlife/abs…
Excited to see this project finally come together🥳
I used the timing of nucleolar assembly at the 8-cell stage as an assay for concentration-dependent phase separation (doi.org/10.1016/j.cub.2015.0…), but could never explain why they don't appear at the 4-cell stage. Now we know!!🤓
The nucleolus is the largest condensate in the nucleus and the site where ribosomes are built. It has no membrane. It assembles by phase separation, components demixing from the nucleoplasm into a droplet.
So what decides when it forms? 🧵🪱💧
biorxiv.org/content/10.64898…
Thanks to @gwgl1979 for introducing me to the LINC complex 🙏, congratulations to @XiangyiDing for her beautiful work 👏, and shout out to @BioMcGill students Megan Couture and Sara Zdanovskis for their initial characterization of the zyg-12 and sun-1 RNAi phenotypes! 🙌
Congratulations to PhD student @LucasPhilipp1 on his first preprint! 🎉 He used Hi-C data to reconstruct the 3D conformations of dinoflagellate chromosomes 🦠🧬 And contrary to the prevailing model, they aren't liquid crystalline! 😯
biorxiv.org/content/10.1101/…
Congratulations, Vera Ugalde Lab! 🥳🧠
Check out their new paper on how neurons respond to stress by locally synthesizing chaperones in dendrites!
Also, they're hiring, so check them out!
veraugaldelab.net/
Curious about how neurons maintain protein homeostasis in dendrites under proteotoxic stress?
Our latest @NatureComms study reveals stressed neurons localize & translate HSP mRNAs in dendrites, creating on-demand chaperones to correct misfolded proteins.
nature.com/articles/s41467-0…
Bit of a different direction for us, but happy to share a new preprint on how intracellular constraints shape the structure of microbial communities🦠
Fun collaboration with ecologist Fred Guichard @BioMcGill, spearheaded by Brendon McGuinness @QLSMcGill
biorxiv.org/content/10.1101/…
🚨 KITP Program Alert 🚨
Interested in biomolecular condensates? 💧
Want to help shape the future direction of the field? 🤓
@jerelleaj, @ZwickerGroup and I are organizing a program @KITP_UCSB. Apply now!
kitp.ucsb.edu/activities/bio…
The Weber Lab goes green ♻️ with @My_Green_Lab 🥈 Huge shout-out to PhD student @Pengashi who spearheaded this effort! #MyGreenLabCertification
Six @mcgillu labs, including four affiliated with #McGillScience, receive My Green Lab certification after a year-long process.
Congratulations to the Abouheif, Barrett, Bui, and Weber labs! 👏👏👏
@RDHBarrett @ehab_abouheif @weber_lab
Full story: reporter.mcgill.ca/sustainab…
If you want to join us, check out the program here: bit.ly/greenlabcert
Congratulations, @Pengashi! 🎉 🙌 So proud of the hard work and persistence you've shown, and excited to see where your project goes next! 🪱💧👨🏻🔬
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Had fun writing this perspective for @JMolBiol with @omc111, (twitterless?) Jorg Gsponer, @LiamHoltLab, @schong_ustc and @bsabari. 🦠💧🤓
Special thanks to @kriwacki and @SElbaumG for organizing!
doi.org/10.1016/j.jmb.2023.1…
Check out my friend and colleague's new lab @LMU_Muenchen @EESLMU1!
@Guse_Lab is doing very exciting work on coral-dinoflagellate symbiosis 🪸🦠
We are hiring! Join us in 2023 at the @LMU_Muenchen @EESLMU1 to work an exciting projects aiming to uncover the mechanisms, ecology and evolution of coral endosymbiosis using @AiptasiaSymRes #symbiosis. We are seeking Postdocs and an animal caretaker: guselab.de/join-us/
🚨Abstract and scholarship deadlines are *today*!🚨
Don't miss out!
Explore emerging #PhaseSeparation #GenomeOrganization research with field leaders @KeystoneSymp #BiomolecularCondensates: Emerging Cellular and Biophysical Roles, this January in Vancouver! keysym.us/KSBioCondensates23 #KSBioCondensates23
Explore emerging #PhaseSeparation #GenomeOrganization research with field leaders @KeystoneSymp #BiomolecularCondensates: Emerging Cellular and Biophysical Roles, this January in Vancouver! keysym.us/KSBioCondensates23 #KSBioCondensates23
Check out this Tweetorial from my co-author @SaganLab 🤓
Hey Virologists! Have you been hearing about phase separation and wondered what it is or how it might be important in the infectious cycle? I paired up with the amazing biophysicist @weber_lab to review the topic for you! 1/7
cell.com/trends/biochemical-…
WeberLab@McGill retweeted
Hey Virologists! Have you been hearing about phase separation and wondered what it is or how it might be important in the infectious cycle? I paired up with the amazing biophysicist @weber_lab to review the topic for you! 1/7
cell.com/trends/biochemical-…
Hey Biophysicists! We've heard a lot (too much😬) about viruses lately, but they're interesting for reasons beyond public health. Turns out, viruses are master architects of biomolecular condensates! Virologist @SaganLab and I teamed up on this review:
authors.elsevier.com/sd/arti…