@txurv

Asst. Prof. @uni_copenhagen & @COPSAC_com | PhD @microUCPH | Previously @TTUHSCSurgery | Microbial interactions, Biofilms, Polymicrobial infections, Microbiome

 Copenhagen, Denmark
www1.bio.ku.dk/english/staff/?pure=en/persons/474480
Joined November 2014
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124Media
Urvish Trivedi retweeted
Lingchong You@lingchongyouOct 8
1/ Even bacterial communities can get caught in a bad romance they just can't get over. A brief encounter with antibiotics can leave a lasting ecological memory of resistance plasmids persisting for weeks after the drug is gone. @DukeBiodesign @DukeUBME nature.com/articles/s41467-0…

Ecological memory of prolonged plasmid persistence after transient antibiotic exposure

Nature Communications - Zhou, Weiss and colleagues show that a brief antibiotic pulse can prolong plasmid persistence by removing plasmid-free competitors, creating an ecological memory that may...

nature.com
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Urvish Trivedi retweeted
Basler Lab@Basler_LabOct 7
When Pseudomonas is attacked, it strikes back! Outer membrane damage triggers a tit-for-tat T6SS retaliation via TagQ/TagR protein complex assembly, activating the PpkA kinase. Congrats to Maxim & team for uncovering this fascinating mechanism! nature.com/articles/s41467-0…

Membrane damage induces TagQ/TagR complex-mediated H1-T6SS assembly in Pseudomonas aeruginosa

Nature Communications - The H1-T6SS of Pseudomonas aeruginosa assembles in response to membrane damage. Here, the authors show that this response mechanism is regulated by the formation of a...

nature.com
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Urvish Trivedi retweeted
Kevin Forsberg@kvnforsbergJul 2
Humans and bacteria share strategies to defend against viruses. We wondered: could they use each other's genes? Yes, both can! Bacteria can use human immune genes to defend against phages AND Human cells can use bacterial genes for viral defense. biorxiv.org/content/10.64898…

Bacterial and human exonucleases mediate interkingdom antiviral immunity

All kingdoms of life have developed strategies to limit viral infection[1][1],[2][2]. In humans, interferons induce a suite of antiviral factors that collectively provide immunity[3][3]. Some human...

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Micro-scale spatial metagenomics opens a new era in microbiome ecology dlvr.it/TRrM4y
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Urvish Trivedi retweeted
Jihoon Han@jihoon_han_phdFeb 18
Excited to share a preprint from my postdoc work in @seth_shipman’s lab! We developed Detectrons — programmable biosensors that convert RNA signals into stable DNA barcodes inside living cells, enabling multiplexed RNA sensing. 🧵👇 biorxiv.org/content/10.64898…
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Urvish Trivedi retweeted
Avigail Stokar-Avihail@AAvihailFeb 6
Eugene Koonin @AudeBer discuss why some bacterial immune systems have no counterparts in eukaryotes, whereas a small subset of comparatively rare systems was co-opted as key elements of eukaryotic innate immunity 🦠🛡️🧍🏽‍♀️
Nature Reviews Microbiology@NatureRevMicroFeb 6
New online! The paradox of immune systems conservation between prokaryotes and eukaryotes dlvr.it/TQnv63
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Yup: Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism cell.com/neuron/fulltext/S08…

Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism

Claims that the gut microbiome causally contributes to autism regularly appear in the scientific literature and popular press. Mitchell et al. critically examine influential studies underpinning...

cell.com
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Urvish Trivedi retweeted
Antonio Camargo@apcamargo_6 Nov 2025
🚨New preprint out! We present a foundational genomic resource of human gut microbiome viruses. It delivers high-quality, deeply curated data spanning taxonomy, predicted hosts, structures, and functions, providing a reference for gut virome research (1/8) biorxiv.org/content/10.1101/…
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What if we could use precision #microbiome editing in vivo to turn harmful gut microbes into allies against disease? We did it using #CRISPR Transposon & mobilome engineering. With @harriswangnyc and Tyler Perdue. In @natBME 👉 nature.com/articles/s41551-0… 👉 innovativegenomics.org/news/…

Precise virulence inactivation using a CRISPR-associated transposase for combating Enterobacteria...

Nature Biomedical Engineering - A self-transmissible CRISPR-associated transposase system encodes a nanobody payload to treat Shiga toxin infections.

nature.com
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Urvish Trivedi retweeted
Sternberg Lab@SternbergLab24 Jul 2025
1/16 New pre-print from the Sternberg Lab! We uncover how temperate phages can use RNA-guided transcription factors to remodel the flagellar composition of their bacterial host and enhance their fitness. Find the preprint and full story here: tinyurl.com/mshwjd77
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Our @MolecularCell Spotlight on the Hailong anti-phage system from the Kranzusch lab! This defense uses "ssDNA tripwires" to trigger toxic ion channels 🧬⚡☠️ Fun write with Johannes Kühn!!
Molecular Cell@MolecularCell7 Jul 2025
(Hai)long story short: Phages trip the DNA wire—Snap! dlvr.it/TLn69h
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🧫 Save the Date! We’re excited to announce an upcoming scientific seminar organised by our Early Career Team, with a spotlight on host–microbe crosstalk. Join us for a day of cutting-edge insights, discussion, and networking! Registration is open now - cphgut.ku.dk/events/seminar-…
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Urvish Trivedi retweeted
Gianmarco Piccinno@gpiccinn3 Jun 2025
Happy to share that our study on gut microbiome associations with colorectal cancer (CRC) is out in @NatureMedicine! (doi.org/10.1038/s41591-025-0…).

Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level...

Nature Medicine - An analysis of 18 metagenomic datasets of individuals with colorectal cancer, adenomas and healthy controls yields improved cancer prediction accuracy based solely on gut...

nature.com
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Urvish Trivedi retweeted
Huiluo Cao 曹慧荦@hlcao27 May 2025
Distinguishing among evolutionary and ecological processes shaping microbiome dynamics | The ISME Journal | Oxford Academic academic.oup.com/ismej/advan…

Distinguishing among evolutionary and ecological processes shaping microbiome dynamics

Abstract. Evolution is defined as the change in allele frequency over time as a result of either neutral processes, such as genetic drift, or as an adaptiv

academic.oup.com
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Urvish Trivedi retweeted
Segata Lab@cibiocm18 Apr 2025
OPEN CALL for PhD positions in our lab through the @semm_it program: 1️⃣ Microbiome signatures of early on-set colorectal cancer 2️⃣ High-resolution computational metagenomics for the study of human microbiome transmission More info: semm.it/education/open-posit… Apply by June 9!
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📣Free event about #microbes👏 #Ecology & Cocktails: Without microbes, animals can't do much🦠 By Professor Tom Gilbert followed by an ecology open #mic night🎤 and an interactive #art activity! May 15 at 18-24 @HusetKBH Read more 👇 huset.kk.dk/events/ecology-c… @GrundforskFond
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Urvish Trivedi retweeted
Mizrahi Lab@LabMizrahi14 Apr 2025
Our new preprint, "Spatial constraints drive amylosome-mediated resistant starch degradation by Ruminococcus bromii in the human colon" is now on bioRxiv! Key findings in the thread below below biorxiv.org/content/10.1101/….
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Urvish Trivedi retweeted
Foster Lab@foster_lab14 Apr 2025
Our latest paper is out in science advances discussing cell division and morphogenesis control in S. aureus. Massive congratulations to Mariana and all of our other authors and collaborators!! science.org/doi/10.1126/scia…

Control of morphogenesis during the Staphylococcus aureus cell cycle

Staphylococcus aureus tightly controls division proteins to maintain cell morphology during the cell cycle.

science.org
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A large-scale literature review to which I contributed was recently published in Nature Medicine!! "Clinical translation of microbiome research." nature.com/articles/s41591-0…

Clinical translation of microbiome research

Nature Medicine - This Review summarizes recent and compelling examples of microbiome-based interventions that are ripe for clinical adoption while also discussing the challenges and opportunities...

nature.com
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Urvish Trivedi retweeted
José R Penadés@jrpenades27 Mar 2025
If you are interested in phage satellites, we hope you'll enjoy this. Fun collaboration with the Rocha, Seed, Bikard, and Chen labs! nature.com/articles/s41579-0…

Genetics, ecology and evolution of phage satellites

Nature Reviews Microbiology - In this Review, Penadés et al. explore the genetics, potential origins and life cycle of phage satellites, and they discuss the impact of these elements on the...

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