T cells | Receptor signaling | Immunotherapy | RIPR | Lab at University of Oxford, CAMS-COI, NDM

Oxford, England
Joined September 2016
Ricardo A. Fernandes retweeted
Huge Congratulations to Dr Christina Heroven (@acheroven) on being awarded a 5-year Early Career Fellowship from @wellcometrust🎉! Christina is part of @theRafLab here at COI & we're excited that she'll be sticking around for longer. Find out more here: camsoxford.ox.ac.uk/news/chr…
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Ricardo A. Fernandes retweeted
Happy to share the newest paper from our lab. Led by technician extraordinaire Aidan Tousley (soon to be an MD/PHD student!), this manuscript details our attempts to reimagine the structure of CARs to improve their specificity and efficacy. rdcu.be/c7avS
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Ricardo A. Fernandes retweeted
We were pleased to welcome the delegation led by Prof. Tao Dong, director of @CAMS_COI_Ox, and Mr. Darren Nash, associated head of @NDMOxford from @UniofOxford to visit BGI Group, exchanging views with our Co-founder and Chairman Wang Jian, for a brighter future of cooperation.
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Ricardo A. Fernandes retweeted
Pleased to share the most recent work from our group published today @NatImmunol nature.com/articles/s41577-0…
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Ricardo A. Fernandes retweeted
It's almost become #fancy to do #scTCRseq and make conclusions on #specificity ...we are no where close to it...read this carefully. #Amazing #TCRs nature.com/articles/s41577-0…
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Ricardo A. Fernandes retweeted
📢 Applications are open for an Oxford-BMS Research Fellow. Join a rapidly expanding institute & @theRafLab, leading development of proteins to control checkpoint signalling in T cells #AcademicJobs #AcademicTwitter #ResearchFellow #OxfordJobs #JobAlert ndm.ox.ac.uk/jobs#159502
Ricardo A. Fernandes retweeted
📢 Join us as a Research Assistant to establish a Protein Production Platform with @theRafLab. Background in biochemistry, protein science or related fields required. Initially 2 yrs fixed. Salary GRADE 6: £29,614 - £35,326. Apply before 5th August. ndm.ox.ac.uk/jobs#159439
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Ricardo A. Fernandes retweeted
🚨 Monday Morning COI #JobAlert: We have several open job adverts to come and work with us at the CAMS-Oxford Institute. Apply via ndm.ox.ac.uk/jobs. #OxfordJobs #OxfordAcademics #AcademicChatter #AcademicJobs #Academia #ResearchAssistant #Bioinformatician #ResearchFellow
Ricardo A. Fernandes retweeted
last day to apply to come join our wonderful team (with a grumpy PI) jobs.ac.uk/job/CGP642/resear…
Ricardo A. Fernandes retweeted
Professors Shankar Balasubramanian and David Klenerman from @ChemCambridge have been awarded the @MillenniumPrize for their development of next-generation #DNA sequencing: bit.ly/3f1QCtH @illumina #MTP2020 #MillenniumPrize #InnovationsForABetterLife
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Ricardo A. Fernandes retweeted
Our paper is out today in Science Signaling, we looked at how IL-10's binding affinity affects its biological activities! stke.sciencemag.org/content/…
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Ricardo A. Fernandes retweeted
Very excited to share our work on IL-10 out today in @ScienceMagazine! We solved the cryo-EM structure of the IL-10 receptor complex and used it to design myeloid-selective IL-10 variants that uncouple its pro- and anti-inflammatory effects science.sciencemag.org/conte…
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Ricardo A. Fernandes retweeted
Stanford's Innovative Medicine Accelerator is hiring a Director of Protein Engineering to help the campus discover and create new protein therapeutics! Hope you will apply for this exciting opportunity! careersearch.stanford.edu/jo…
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Ricardo A. Fernandes retweeted
Virtually every aspect of the COVID vaccine, from the lipid nanoparticles to the mRNA technology, was developed in academic labs using public funds. But in the public's mind the credit goes to companies like Moderna/Pfizer. This is a missed opportunity to celebrate basic research
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Ricardo A. Fernandes retweeted
Congratulations to superstar grad student @CalebGlassman on this beautiful story, great to finally see it out! A game changer for the use of IL-12 in cancer
Our paper on IL-12 and IL-23 is out today in @CellCellPress! Using structures of the IL-12 and IL-23 receptor complexes, we engineered versions of IL-12 that support T cell anti-tumor immunity without NK cell toxicity authors.elsevier.com/a/1cc0a…
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Ricardo A. Fernandes retweeted
Register for #CIMT2021 and hear Ugur Sahin @BioNTech_Group on the scientific journey of developing an mRNA coronavirus vaccine in 10 months. #COVID-19 − #immunooncology cross-talk at meeting.cimt.eu
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Ricardo A. Fernandes retweeted
SCI member Chris Garcia and colleagues engineered a molecule called RIPR-PD1 that inhibits both tonic and ligand-activated signalling, and demonstrates increased therapeutic efficacy over anti-PD1 in mouse tumor models. go.nature.com/39187rb @nature
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Ricardo A. Fernandes retweeted
🔊 This #3 top tweet in our 2020 tweet countdown features an alternative approach for attenuating cell-surface receptor signaling, conducted by Dr. Christopher Garcia and @StanfordDeptMed scientists. xitter.cf/Immune_News/status/131…
✨ New in @nature! Dr. Christopher Garcia and @StanfordDeptMed scientists present an alternative approach for attenuating cell-surface receptor signaling, termed #ReceptorInhibition by phosphatase recruitment. #antibodies go.nature.com/3dO6ddZ
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Ricardo A. Fernandes retweeted
We are delighted to announce the new organizers and speakers for the 2021 #globalimmuno talks 👇 Updates (including titles) will be posted here: labs.biology.ucsd.edu/zuniga… For notifications on recorded talks pls subscribe to our YouTube channel: youtube.com/c/GLOBALIMMUNOTA… Please RT
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Ricardo A. Fernandes retweeted
This week, our guest in the online journal club is Ricardo Fernandes @theRafLab from @NDMOxford . He will talk about his recent paper in @nature on a new way of immunomodulation by "receptor inhibition by phosphatase recruitment (RIPR)". Wed, 5pm CET. nature.com/articles/s41586-0…
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