I am deleting my Twitter account. Please follow me on BlueSky (@wnoble.bsky.social).
William Stafford Noble retweeted
Interested in de novo peptide sequencing from #massspec #proteomics data? Check out our latest #preprint about Casanovo!
👉 doi.org/10.1101/2023.01.03.5…
That's right folks - it's time for another #tweetorial 🧵 (1/9)
William Stafford Noble retweeted
Want to learn more about the state of the art in de novo peptide sequencing at #ASMS2023?
Come check out our:
- Evening workshop #17 for a Casanovo tutorial on Monday
- Talk at the AI session on Wednesday
#TeamMassSpec
Interested in de novo peptide sequencing from #massspec #proteomics data? Check out our latest #preprint about Casanovo!
👉 doi.org/10.1101/2023.01.03.5…
That's right folks - it's time for another #tweetorial 🧵 (1/9)
William Stafford Noble retweeted
Congratulations to Lincoln Harris on being awarded an NRSA fellowship!
Casanova is the new state of the art in de novo peptide sequencing. biorxiv.org/content/10.1101/…
William Stafford Noble retweeted
Check out Polarbear🐻❄️, a method to predict the missing scATAC-seq profiles just based on scRNA-seq, and vice versa. 🐻❄️ also derives matching in between scRNA-seq and scATAC-seq profiles, enabling integration of different types of single cell measurements. link.springer.com/chapter/10…
William Stafford Noble retweeted
Our paper about building spectral libraries from DIA data is officially out @JProteomeRes! Thank you to everyone who worked on this and to our reviewers for their feedback, I'm very excited about the final product.
Building Spectral Libraries from Narrow-Window Data-Independent Acquisition Mass Spectrometry Data #JProteomeRes pubs.acs.org/doi/10.1021/acs…
William Stafford Noble retweeted
Obligatory post following a bioRxiv submission. In this work we show that 1) PSM-level FDR estimates in practice are invalid and 2) a simple variant of the peptide-level FDR estimate protocol can yield a significantly greater number of peptide detections
Detecting more peptides from bottom-up mass spectrometry data via peptide-level target-decoy competition | buff.ly/3wmZcKP #proteomics
William Stafford Noble retweeted
Our featured article: Navigating the pitfalls of applying machine learning in genomics go.nature.com/3D55JuZ #Review by @seawhalen, @jmschreiber91, William S. Noble & Katherine S. Pollard @GladstoneInst @Stanford @UW
@uwgenome @UCSF @czbiohub
The state of the art in de novo peptide sequencing has just advanced: meet Casanovo, a transformer model that translates from the sequence of peaks in a spectrum to the sequence of amino acids in a peptide. biorxiv.org/content/10.1101/…
William Stafford Noble retweeted
Not going to lie. Part of the reason I created an account was to promote this preprint of mine.
We have created a new score, MS1Connect, that measures the similarity between pairs of mass spectrometry runs solely using MS1 scans and without any peptide identifications. 🧵 1/9
MS1Connect: a mass spectrometry run similarity measure biorxiv.org/cgi/content/shor… #bioRxiv
Excited for another 5 years of studying genome 3D architecture! newsroom.uw.edu/news/nih-fun…
Thanks for funding Percolator, CZI.
#Opensource software is essential to science. That’s why we’re awarding 23 grants to support open source tools that accelerate biomedical research and serve the larger scientific community. chanzuckerberg.com/newsroom/…
My lab has an open position for a software developer to support our Percolator machine learning engine for mass spectrometry analysis.
uwhires.admin.washington.edu…
William Stafford Noble retweeted
I'm honored to have received an @asmsnews postdoctoral career development award. asms.org/about-asms-awards/p…
Big thanks to all my mentors (@KrisLaukens, @goethals, @thabangh, @Pdorrestein1) and collaborators (@compomics, @dtabb73, many more) over the years.
William Stafford Noble retweeted
Our latest @JProteomeRes paper was featured on @GenomeWeb, which is pretty cool 😎 genomeweb.com/mass-spec/uw-t…
The MEME Suite of motif-based sequence analysis tools was the subject of my very first bioinformatics paper way back in 1996. The web server (meme-suite.org/) has been in operation ever since. Now you can install it directly on your Mac: "sudo port install memesuite"
I have postdoctoral positions in machine learning and genomics/proteomics available in my lab. noble.gs.washington.edu/post… Come find me if you are at #ISMBECCB19
William Stafford Noble retweeted
The ENCODE imputation challenge is now live!
Sign-up, form teams, and impute your way to cash awards sponsored by @LifeEpigenetics!
synapse.org/encodeimpute