Father of 4 boys, cardiologist, clinical researcher- outcomes, clinical trials, health policy & innovative methods; Director DCRI; Vice Dean, Duke School of Med

Duke University
Joined March 2011
Adrian “WE NEED RCTS!” Hernandez retweeted
📢@AllianceCardio Test 2 Treat study led by @NPagidipati & @Nishant_ShahMD will present a late-breaking session @American_Heart #ScientificSessions26 on 11/9. The @PCORnetwork study explored ways to improve LDL-C testing & treatment for patients w/ #ASCVD🔗cardiohealthalliance.org/new…
3
6
112
Adrian “WE NEED RCTS!” Hernandez retweeted
Medical research gives patients hope, advances new treatments and strengthens communities. So pleased to see so many leaders and volunteers alongside @American_Heart Volunteer President @manesh_patelMD in Washington, D.C., advocating for independent science and continued support of medical research.
Advocates gathered on Capitol Hill to share why medical research matters for patients, families and communities nationwide. Every breakthrough starts with research. @RallyforNIH #FundNIH Heartpowered.org/SaveScience
6
17
1,212
Adrian “WE NEED RCTS!” Hernandez retweeted
The DCRI will lead the SYMPHONY Consortium, a national network testing AI agents for heart failure care across diverse health systems and rural sites. The goal: determine whether these tools are safe, effective, equitable, and scalable. duke.is/m/rw9v @american_heart
Nearly half of U.S. counties have ZERO cardiologists. Millions of Americans have no access to cardiovascular care. And every year, there are 200,00+ preventable deaths from cardiovascular disease. ARPA-H is ending this with ADVOCATE. We’ve picked the teams building an FDA-authorized AI system for real-world heart care. Building toward an AI cardiologist for every American—always ready, clinically trusted, specialist-backed. Not tweaking the old system. Building the next one. Learn more ➡️ arpa-h.gov/explore-funding/p…
1
5
9
1,906
Adrian “WE NEED RCTS!” Hernandez retweeted
Ahead of Beyond the Endpoint’s Sept. 9 episode reflecting on 30 years of the DCRI, founder Robert Califf and current executive director Adrian Hernandez play a game of "what kind of bread are you?" Multigrain, sourdough, ciabatta...watch to find out who's who. 🍞
4
7
1,186
Adrian “WE NEED RCTS!” Hernandez retweeted
WOW! Hopefully this quote bodes well for other efforts: “The findings provide important new evidence on the relationship between Lp(a) lowering and cardiovascular outcomes.” And remember, ASOs are NOT RNAi! novartis.com/news/media-rele…
10
12
2
105
16,327
Adrian “WE NEED RCTS!” Hernandez retweeted
💬 Editorial by @JAMAplusTrials Editor in Chief Alison J. Huang, MD, MAS, Thomas G. Travison, PhD, and JAMA Senior Editor Derek C. Angus, MD, MPH: #PragmaticTrials are intended to support real-world clinical decision-making, but the term is used inconsistently across studies. A pragmatic orientation may improve the applicability of #ClinicalTrials to routine care, yet it does not justify weaker methods or reduced rigor. 📣 This September’s JAMA+ Trials Theme of the Month examines ongoing confusion and debate in pragmatic trial research, including how eligibility, intervention delivery, outcome assessment, and analysis align with pragmatic goals. Clearer design and reporting may help clinicians and health systems judge whether trial findings are usable in practice. 🔗 ja.ma/4x2jpmk
3
16
65
14,220
Adrian “WE NEED RCTS!” Hernandez retweeted
Dr. Marat Fudim and Dr. C. Michael Gibson discuss the MUSIC-HFpEF trial: Data from the first-in-human Phase 1/2a trial demonstrated that single intracoronary infusion of AAV1.SERCA2A was safe and associated with reductions in resting and exercise-induced PCWP in patients with hemodynamically confirmed HFpEF. Watch video here: clinicaltrialresults.org/wp-…
1
3
25
3,530
Adrian “WE NEED RCTS!” Hernandez retweeted
📣 In this week's PCT Grand Rounds, Haider Warraich of @ARPA_H will present “Evaluating Clinical Agentic AI.” Join us! #pctgr 🔗 duke.is/pctnews20260826
2
1
1
146
Adrian “WE NEED RCTS!” Hernandez retweeted
NEWS: Dr. Wendy Weber to serve as director of the National Center for Complementary and Integrative Health. Read the full story ➡️ bit.ly/45L1N3q
8
18
4
95
38,449
Adrian “WE NEED RCTS!” Hernandez retweeted
The CardioHealth Alliance is excited to welcome UCLA Health as a new health system collaborator! 🎉UCLA Health’s support will help advance efforts to develop and implement groundbreaking research initiatives aimed at improving cardiometabolic outcomes: cardiohealthalliance.org/new…
2
7
10
1,641
Adrian “WE NEED RCTS!” Hernandez retweeted
Congrats to DCRI's Mark Darby, whose stunning Emerald Isle sunrise photo was selected as the latest winner of @WorkingatDuke’s Duke Time Off photo contest! See Mark's photo and learn how Duke faculty and staff can participate: today.duke.edu/2026/06/sunri…
2
4
206
Adrian “WE NEED RCTS!” Hernandez retweeted
Looking forward to Co-Chairing this exciting Think Tank on HF prevention with the incomparable @JavedButler1
The DCRI and @CVCTForum have launched "Pathway to Prevention," an initiative to build regulatory and clinical pathways for cardiovascular prevention therapies. Three programs + multiple stakeholders = closing the gap between science and policy. dcri.org/news/dcri-cvct-laun… #Prevention
1
4
12
1,163
Adrian “WE NEED RCTS!” Hernandez retweeted
The DCRI and @CVCTForum have launched "Pathway to Prevention," an initiative to build regulatory and clinical pathways for cardiovascular prevention therapies. Three programs + multiple stakeholders = closing the gap between science and policy. dcri.org/news/dcri-cvct-laun… #Prevention
2
1
4
1,519
Adrian “WE NEED RCTS!” Hernandez retweeted
Post win interview with Collin Hernandez and Austin Gunsch
1
5
208
Adrian “WE NEED RCTS!” Hernandez retweeted
The cardiology community mourns the loss of Dr. Eugene Braunwald, a towering figure whose work shaped modern cardiovascular medicine. From foundational discoveries in heart failure to Braunwald’s Heart Disease, his legacy will guide generations to come. A true giant in our field.
8
102
15
335
23,309
Adrian “WE NEED RCTS!” Hernandez retweeted
The #CardioHealthAlliance was created to deliver innovation, information, & impact, leveraging electronic health records & academic & industry partners’ expertise to ask & answer important research questions. The Alliance’s @TheMahaf explains 🎥youtu.be/wV-4__Emtb0?si=3MVf…
1
3
103
Adrian “WE NEED RCTS!” Hernandez retweeted
The Medical Alumni Association Distinguished Awards were created to recognize those who make important contributions to the establishment and growth of the four-year medical school and to the world of medicine. 🔗 Read more about this year's winners: medschool.duke.edu/about-us/…
2
7
561
Adrian “WE NEED RCTS!” Hernandez retweeted
Dr. Sreekanth Vemulapalli and Dr. C. Michael Gibson discuss the use of AI for cardiovascular event adjudication: A hybrid AI-human approach effectively reproduced original trial primary endpoint and effect size, outperforming GPT-4 alone. #ACC26 Watch video here: clinicaltrialresults.org/dr-…
8
1
20
6,473
Adrian “WE NEED RCTS!” Hernandez retweeted
Day 2 of #ACC26 delivered! From cardiogenic shock to AI-powered arrhythmia care, the science didn’t stop. There is still time to find us at Booth 1301 tomorrow. Explore our capabilities and learn how to partner with us on your next trial. dcri.org/acc #CardioX
2
7
608
Adrian “WE NEED RCTS!” Hernandez retweeted
Need leading experts to design your next global #CV trial? Let's talk. The DCRI brings decades of expertise to every collaboration. Reach out to Claire Beard to schedule a meeting at #ACC26. [email protected] | Learn more: dcri.org/acc #trialdesign #CardioX
4
6
746