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You can tell how mature someone is by noticing how little they need you to agree with them.
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Totally agree. Sometimes the biggest risk you take is not taking risks. Now feels like that time. Predictable low variability path to slow decline or thoughtful risk taking
A CEO from one of our portfolio companies shared this with their team. I’m re-sharing it with their permission, because it resonated and reflects what all founders and CEOs should be communicating.
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We are living through a period of compounding change. And in moments like this, the biggest risk is no longer making the wrong decision. It is moving too slowly while the world moves around you.
There are two paths. We can play defense:
- Protect what we have
- Optimize what works
- Wait for clarity
It feels safe. It isn’t.
Or we can play offense:
- Learn faster than the environment changes
- Use new tools to solve old problems in better ways
- And create entirely new strategies and businesses
That’s where the opportunity is.
Challenge yourself to do things faster and better than you have ever attempted. Stay uncomfortable. Stay on the front foot.
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The Taco Bell in Pacifica, CA
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It’s interesting to me that when we look for guidance on big topics like, ”What does it mean to be a good person?”, or “What makes for a meaningful, worthwhile life?”, many of the canonical texts we regularly refer to are very old. Nicomachean Ethics, Meditations and the Bible, for instance, were written ~2K years ago.
What should we make of this? Should we ‘expect’ our answers to these questions to evolve? I wrote some thoughts (and questions) on moral imagination. Link in reply.
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It only takes five minutes to break the cycle.
Five minutes of exercise and you are back on the path. Five minutes of writing and the manuscript is moving forward again. Five minutes of conversation and the relationship is restored.
It doesn't take much to feel good again.
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Learn to go first.
Introduce yourself.
Ask them out.
Host the event.
Voice an idea.
Tell people what you want.
ㅤ
You’ll face more rejections when things go wrong, but you’ll get all of the credit when things go right. The world rewards those who go first because so few people do.
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Alcohol shrinks the brain
This association is detectable in people who only drink one or two units per day, and more drinks means more atrophy:
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Jay Yang@Jayyanginspires1 Apr 2025
United States
United StatesConnected via United States App StoreAccount-level information, not a live location or per-post device.
A question that lives rent free in my head...
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Negativity is boring. What’s needed is for more people to get excited about what could exist in the world, and then go and make it happen. There are still so many interesting problems to solve!
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It’s beautiful today in San Francisco - high of 63 degrees in January. Days like today remind me why I’m so happy to live here.
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The only punch thrown tonight.
@nucleusgenomics
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Very pleased to announce our first winner here — @subehq!! See you tomorrow my man!
Who will be next?!!!??!!?
FREE TICKETS TO JAKE PAUL VS MIKE TYSON
@nucleusgenomics will be at the @jakepaul and @MikeTyson through our partnership with @JLeonLove.
We have TWO general-admission tickets who will sit with the Nucleus Team.
Whoever retweets this post + comments on the most compelling reason on why they should go will win the tickets!!!!
Submissions end tonight at 9pm PT.
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FREE TICKETS TO JAKE PAUL VS MIKE TYSON
@nucleusgenomics will be at the @jakepaul and @MikeTyson through our partnership with @JLeonLove.
We have TWO general-admission tickets who will sit with the Nucleus Team.
Whoever retweets this post + comments on the most compelling reason on why they should go will win the tickets!!!!
Submissions end tonight at 9pm PT.
RT @anuatluru: one of the greatest blessings in life is having friends and family that will be mad at you if you don’t pursue your dreams
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Woah, Neptune is actually light blue! We'd been misinformed for 35 years!
The well-known images from Voyager 2 were not accurately colour balanced & apparently they also increased the contrast way more than for the Uranus images. Here the corrected ones:
ras.ac.uk/news-and-press/new…
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Legendary Japanese filmmaker AKIRA KUROSAWA with some great advice for writers everywhere.
























