@UNC Alumna | @bcmhouston PhD Candidate | Interests: Venom, Biomolecular Condensates, Aging and Neurodegeneration
Houston, TX
Joined October 2019
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Sovanny Taylor (Sophie) retweeted
Announcing the joint IDPSeminars / BPS IDP Subgroup Trainee Symposium Speakers!
Join us on Mar 27, 12–2pm CST for 6 exciting talks focused on Intrinsically Disordered Proteins as part of #BiophysicsWeek2025 with the @BiophysicalSoc
Sign up now at docs.google.com/forms/d/1L_K…
ALT IDPSeminars/BPS IDP Subgroup symposium. March 27th 2025 at noon central time. Speakers are Ella Mozier, Sara Bologna, Borna Novak, Hamidreza Ghafouri, Ankith Sharma and Ananya Chakravarti!
Sovanny Taylor (Sophie) retweeted
RNA-binding proteins and glycoRNAs form domains on the cell surface for cell-penetrating peptide entry: Cell cell.com/cell/fulltext/S0092…
Sovanny Taylor (Sophie) retweeted
Curious how biocondensates localize ions? We found that condensates selectively bind and localize both chaotropic anions and kosmotropic cations. This
alters the condensate composition, interface potential and RNA duplex stability inside. By @IrisSmokers
biorxiv.org/content/10.1101/…
Sovanny Taylor (Sophie) retweeted
Congrats to Nick DeCleene on defending his thesis under the guidance of Alison Bertuch @TexasChildrens & @BCMHouston, and for donating stem cells @nmdp_org just a week after graduating! Whether in the lab or donating for a good cause, he is an inspiration❤️#StemCellDonor #PhDLife
Sovanny Taylor (Sophie) retweeted
m6A sites in the coding region trigger translation-dependent mRNA decay dlvr.it/TGfTnN
Sovanny Taylor (Sophie) retweeted
Proteolethargy is a pathogenic mechanism in chronic disease: Cell cell.com/cell/fulltext/S0092…
Sovanny Taylor (Sophie) retweeted
Identification of a factor that accelerates substrate release from the signal recognition particle | Science science.org/doi/10.1126/scie…
Sovanny Taylor (Sophie) retweeted
Online Now: lncRNAs maintain the functional phase state of nucleolar prion-like protein to facilitate rRNA processing dlvr.it/TGNsHh
Sovanny Taylor (Sophie) retweeted
New finding on APOE today in @CellCellPress: APOE2 and the Christchurch mutation are defective in LDLR binding. Decreased lipidated ApoE-receptor interactions may protect against the pathogenicity of ApoE and its lipid cargoes in lysosomes cell.com/cell/fulltext/S0092…
Sovanny Taylor (Sophie) retweeted
We are getting ready for the online symposium with the Biophysical Society. Here is the registration (no fees) link:
biophysics.org/upcoming-netw… @BiophysicalSoc
Sovanny Taylor (Sophie) retweeted
Cancer cells often harbor oncogenes outside chromosomes on extrachromosomal DNA (ecDNA), which is unevenly inherited by dividing cells. Today we report in @Nature that collectives of ecDNAs are inherited together by dividing cancer cells. 1/
nature.com/articles/s41586-0…
Congrats to @JLeeLab !!! 🎉
Fahim and Marcus et al. @JLeeLab @bcmhouston developed live-cell #microscopy approaches to address whether co-localized enzyme factors are forming biochemically relevant interactions within RNA–protein condensates. hubs.la/Q02TgxV-0
#Biochemistry #RNAbiology
Sovanny Taylor (Sophie) retweeted
I’m so excited to welcome MrTAC to the world of targeted protein degradation! We created a chemical inducer of arginine methylation that can be used to degrade proteins in lysosomes 💊 So grateful for everyone involved in this project 🥳🥳 nature.com/articles/s41589-0…
Sovanny Taylor (Sophie) retweeted
New paper in @ScienceAdvances: We've uncovered the nuclear speckle transcriptome, revealing gene groups with distinct speckle localization properties and that speckles boost splicing for localized transcripts. Thanks to all co-authors! @regevlab science.org/doi/10.1126/scia…
Sovanny Taylor (Sophie) retweeted
📢New paper alert!! With @boothbylab @alexholehouse @fried_lab we take a look at how an entire proteome survives desiccation. TLDR: Desiccation tolerance is encoded in specific residues on the protein surface, and occurs primarily in biosynthetic enzymes. shorturl.at/U5VS1
Sovanny Taylor (Sophie) retweeted
Gesteund door ALS Liga fonds A Cure for ALS doctoreerde @BoeynaemsSteven in 2017 @ Lab Neurobiologie KULeuven/VIB @LuVaDeBo. Nu is hij assistant Professor @bcmhouston @texaschildrens waar bij NIH Innovator Award 2,4 M Dollar ontving om eigen lab verder uit te bouwen. Proficiat!
Sovanny Taylor (Sophie) retweeted
Do you know what I love most about my PhD @JungmannLab? Actually seeing the things I learned from biology textbooks come to life🪄. Check out this DNA-PAINT image of the Golgi, showing both cis (GM130) and trans (TGN38) faces together with peroxisomes. Happy #FluorescenceFriday😊
Literally my favorite author with the best books about the human condition
BREAKING NEWS
The 2024 #NobelPrize in Literature is awarded to the South Korean author Han Kang “for her intense poetic prose that confronts historical traumas and exposes the fragility of human life.”
Sovanny Taylor (Sophie) retweeted
Ryan Flynn @raflynn5 of @HSCRB, an #NIHHighRisk Transformative Research Awardee, will explore how and why #RNA and RNA-binding proteins function on cell surfaces. This research could lead to transformative insights in cell #biology and disease mechanisms. hscrb.harvard.edu/news/flynn…
Ryan Flynn Awarded Prestigious NIH Director's Transformative Research Award | HSCRB
hscrb.harvard.edu
Congratulations @raflynn5 for receiving @NIH_CommonFund's Transformative Research Award! #NIHHighRisk hscrb.harvard.edu/news/flynn…
So happy for @BoeynaemsSteven !!!
Early-stage investigators proposed #innovative high-impact research ideas for the @NIHDirector’s New Innovator Award. See the projects the awardees will pursue: commonfund.nih.gov/newinnova… #NIHHighRisk
ALT Card with text reads: 2024 NIH Director's New Innovator Awardees. NIH Common Fund logo next to headshot of awardees.