@sm00tle

Endocrinologist @SheffieldHosp. Previously @QMULWHRI @NHSBartsHealth. Interests not limited to endocrine hypertension and endocrine tumour syndromes

 London, England
Joined November 2015
  • Tweets87
  • Following174
  • Followers116
6Media
Read the latest article in Endocrine-Related Cancer's #RET Special Collection: 'Genomic testing for RET in the clinic: UK and global perspective' By Louise Izatt @GSTTnhs @KCLBMBioscience 👉 doi.org/10.1530/ERC-24-0230
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Sam O'Toole retweeted
Jun Yang@DrJunYang15 Jan 2025
New consensus on assessing Primary Aldosteronism Medical treatment Outcomes (PAMO), and PAMO in 1258 patients from 28 centres around the world. Grateful to 54 co-authors for collaborating! @Hudson_Research @EndoSocAus @SCSMonash @A5_Adrenal @TheEndoSociety sciencedirect.com/science/ar…
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⭐ Explore our completed collection: Advances and future directions in #pheochromocytoma and #paraganglioma, with the latest research related to genetics, metabolomics, nuclear medicine, preclinical models and mitochondrial dysfunction 👉 ow.ly/6uPk50ShMCU
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Sam O'Toole retweeted
Jun Yang@DrJunYang4 Jun 2024
Sad to leave #ENDO2024. What an amazing meeting it has been, with huge thanks to the staff and leadership team @TheEndoSociety I have indulged in #PrimaryAldosteronism or #mineralocorticoid sessions every day! See everyone at #ENDO2025 in San Francisco.
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From one outstanding leader to another. We are in good hands indeed - as @TheEndoSociety President @StephenHammes passes the gavel to incoming President John Newell-Price. Discovery science, optimizing care, advocacy, education and more.…. Let’s go !!!
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There is a prevalent spectrum of dysregulated and overt primary aldosteronism in low-renin hypertension, that is also prominently regulated by ACTH. Multiple diagnostic and therapeutic implications can be inferred academic.oup.com/jcem/advanc…
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This year amazing @goharmonisation #ENSAT2023 meeting has come to an end. Thank you🙏 @DarkoKastelan and the entire local organising committee for great three days of science and networking in a beautiful location 👏 See you all next year in Palma de Maiorca 😊
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John Newell-Price, MD, PhD, FRCP, has been elected @TheEndoSociety's 2024-2025 president. Five new board members will be joining him in June: bit.ly/3kMKrPT

John Newell-Price, MD, PhD, Elected 2024 - 2025 Endocrine Society President - Endocrine News

Endocrine Society members elected John Newell-Price, MD, PhD, FRCP, as its 2024-2025 President. He will serve as President-Elect for a year beginning in June 2023 before becoming President in June...

endocrinenews.endocrine.org
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A call for @goharmonisation in PA diagnostics: International multicenter survey on screening and confirmatory testing in primary aldosteronism pubmed.ncbi.nlm.nih.gov/3672…

International multicenter survey on screening and confirmatory testing in primary aldosteronism -...

Diversity of the diagnostic steps may lead to an inconsistent diagnosis of PA among centers and limit comparison of evidence for PA between different centers. We expect the impact of this diversity...

pubmed.ncbi.nlm.nih.gov
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MATCH results out now - non-inferiority of molecular imaging to AVS marking a real step forward @QMULWHRI @BartsHospital @CUH_NHS @Soc_Endo @TheEndoSociety #primaryaldo #moretocome nature.com/articles/s41591-0…

[11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary...

Nature Medicine - Comparison of non-invasive [11C]metomidate PET-CT with adrenal vein sampling for predicting biochemical remission of primary aldosteronism showed non-superiority, suggesting that...

nature.com
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Recent paper indicating waking salivary cortisone strongly predicts ACTH stimulation test outcome reducing the need for an ACTH stimulation test in 70% of high risk patients tested for adrenal insufficiency.
NEJM Evidence@NEJMEvidence6 Jan 2023
This prospective study tested use of home waking salivary cortisone levels to predict adrenal insufficiency. Salivary cortisone had diagnostic accuracy similar to that of a standard adrenocorticotropin (ACTH) stimulation test. eviden.cc/3GHaobt #EndoTwitter #MedTwitter
Waking salivary cortisone levels predicted an adrenocorticotropin stimulation test 30-minute serum cortisol level >15.6 mg/dl (>430 nmol/l) as measured by immunoassay with an AuROC of 0.95 (95% CI, 0.92 to 0.97).

ALT Waking salivary cortisone levels predicted an adrenocorticotropin stimulation test 30-minute serum cortisol level >15.6 mg/dl (>430 nmol/l) as measured by immunoassay with an AuROC of 0.95 (95% CI, 0.92 to 0.97).

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1/5 Health Care Providers! We have an excellent #pheo #para patient conference & Awareness Week coming soon.✅out the links for more info. Thx in advance for spreading the word to your patients! 📣🦓❤️ Conference➡️bit.ly/3ROyq81 Awareness Week➡️bit.ly/3C0ptmx
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21/46 The other reason to raise the alarm urgently (noting as above all GPs use accountants) is that's others will have inevitably done the same and bravo to @AISMANewsline for sounding the alarm to @hmtreasury independently.
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🚨Save the date! 🚨 The 21st ENSAT annual scientific meeting 2022 will take place on 29th and 30th September 2022 in Warsaw (Poland). Make sure to have these dates in your calendar. Check details at ensat.org

ENS@T - European Network for the Study of Adrenal Tumours

Adrenal tumours are frequent in the general population but mostly harmless. In rare cases, they can be cancerous and/or associated with hormone excess.

ensat.org
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New consultant post at @SheffieldHosp Full advert and further details available in link below: beta.jobs.nhs.uk/candidate/j…
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Endocrinology consultant post in Sheffield - come join an excellent team in the UK's greenest city healthjobsuk.com/job/v391272… @youngdiab @EarlyCareerEndo
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Only one day to go until the start 🎬 of the #ENSAT annual meeting - this year virtual and joint with the International Adrenal Cancer Symposium. Follow us for updates and highlights. #adrenal #ACC #adrenalresearch #adrenaltumours
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Wishing a Healthy, Happy, & Sweet New Year to all those celebrating! #ShanaTova
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The official @ENSAT Twitter account is now live. Follow us for news and alerts about #adrenal tumours, #ACC #adrenalcancer adrenal #Cushing #hypercortisolism #APA #hyperaldosteronism #pheochromocytoma #incidentaloma
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Goodbye @NHSBartsHealth, @BartsHospital & @QMULWHRI. It's been an amazing decade. Excited for the future and challenges ahead @SheffieldHosp
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