sing (@sing21410089) profile picture

sing

@sing21410089
Joined October 2018
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  • Following10
  • Followers9
Our latest work on acentrosomal microtubules in quiescent neural stem cells is published in @embojournal！ embopress.org/doi/full/10.15… @qiannandeng0520 @sing21410089
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In our new preprint, we show that tumor suppressor Parafibormin plays a novel role in regulating centrosome assembly and cell polarity! @qiannandeng0520 @sing21410089
Centrosome Papers (@CentrosomePub) profile pictureCentrosome Papers@CentrosomePub6 Jul 2021
Centrosome Pre: Tumour Suppressor Parafibromin/Hyrax Governs Cell Polarity and Centrosome Assembly in Neural Stem Cells dlvr.it/S3BV9H
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Here is the press release on our paper from @dukenus! @emboreports duke-nus.edu.sg/allnews/medi…
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Honoured to join GENETICS editorial board as a new Associate Editor in the new subsection “Neurogenesis and bahavior”. @GeneticsGSA Call for papers in neural development, function, plasticity, and behavior!
Genetics Society of America (@GeneticsGSA) profile pictureGenetics Society of America@GeneticsGSA10 Feb 2021
We've got new subsections for your #GENETICS submissions! Our new & enhanced sections are: Molecular Genetics of Development; Neurogenetics and Behavior; Experimental Technologies and Resources; and Computational Resources, Software, and Databases. https://xitter.cf/t.co/dyJ8rGK9na
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Congratulations to @Huang90J @mahekta @qiannandeng0520 for the paper published in @emboreports! “Histone lysine methyltransferase Pr‐set7/SETD8 promotes neural stem cell reactivation” 🎉🎉🎉👍👍👍 embopress.org/doi/full/10.15…
Histone lysine methyltransferase Pr-set7/SETD8 promotes neural stem cell reactivation

Histone lysine methyltransferase Pr-set7/SETD8 promotes neural stem cell reactivation

EMBO Reports - The ability of neural stem cells (NSCs) to switch between quiescence and proliferation is crucial for brain development and homeostasis. Increasing evidence suggests that variants of...

link.springer.com
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My talk on modelling neurodevelopmental disorders in flies at the Australian Developmental Neuroscience Forum (ADNF) is on YouTube at youtu.be/jkf1HgRQqi4
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Proud to announce the 12th Stem Cell Society Singapore on 9-11 Dec 2020 as Chair of the organising committee! Registration for trainees only at SGD25! Submit an abstract for oral presentation! Symposium content remains accessible post-conference. @StemCellSpore @LabFly @4Nscrl
StemCellSocSin (@StemCellSpore) profile pictureStemCellSocSin@StemCellSpore27 Oct 2020
SCSS-JSRM Joint Symposium 2020: Deadline alert! - mailchi.mp/396353fa27fd/scss…
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Excited to share our review article on neural stem cell reactivation published in @plosgenetics: journals.plos.org/plosgeneti… @Huang90J

Waking up quiescent neural stem cells: Molecular mechanisms and implications in neurodevelopmental...

Neural stem cells (NSCs) are crucial for development, regeneration, and repair of the nervous system. Most NSCs in mammalian adult brains are quiescent, but in response to extrinsic stimuli, they can...

journals.plos.org
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Replying to @qiannandeng0520
@qiannandeng0520 Our first bioRxiv paper posted during Chinese New Year holiday! Want to know the structure and function of the primary protrusion of quiescent neural stem cells? Read it at biorxiv.org/content/10.1101/… The story I presented in @apdrc5
Msps Governs Acentrosomal Microtubule Assembly and Reactivation of Quiescent Neural Stem Cells

Msps Governs Acentrosomal Microtubule Assembly and Reactivation of Quiescent Neural Stem Cells

The ability of stem cells to switch between quiescence and proliferation is crucial for tissue homeostasis and regeneration. Drosophila quiescent neural stem cells (NSCs) extend a primary cellular...

biorxiv.org
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Our paper is out #PLOSBiology: CRL4Mahj E3 ubiquitin ligase promotes neural stem cell reactivation dx.plos.org/10.1371/journal.…
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Discovery by @dukenus researchers has implications for further understanding and treating neurodevelopmental disorders in humans: ow.ly/MLg230oxd5N

Gene Regulation Finding Advances Understanding of Neurodevelopmental Disorders

Members of the multiprotein Integrator complex are found to be crucial for healthy brain development in fruit flies.

genengnews.com
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Our paper on the role of Integrator in suppressing dedifferentiation of intermediate neural progenitors back into neural stem cells is out today @CellReports! Here is the press release from @dukenus. duke-nus.edu.sg/allnews/deta…
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Brain expansion promoted by polycomb-mediated anterior enhancement of a neural stem cell proliferation program journals.plos.org/plosbiolog…

Brain expansion promoted by polycomb-mediated anterior enhancement of a neural stem cell prolifer...

A study in fruit flies shows that the anterior expansion of the central nervous system, to form the brain, is driven by Polycomb-mediated repression of Hox genes, resulting in anterior enhancement of...

journals.plos.org
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A nice review on Phosphoinositide Signaling in which our recent eLife paper was cited-Vib regulates asymmetric division of neuroblasts ... Vib cooperates with PI4KIIIa to maintain a PtdIns4P pool on the neuroblast cell cortex for Sph recruitment. jlr.org/content/early/2018/1…
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Come to hear the EMBO Young Investigator Clemens Cabernard's seminar on asymmetric cell division at Duke-NUS on next Monday (19 Nov) at 4-5pm! Nice talk and cool imaging guaranteed! @CabernardLab @MBIsg #CellBiology duke-nus.edu.sg/nbd/event/in…
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My PhD student Jiawen’s paper on Hsp90 is officially out in @StemCellReports this month. Ex-postdoc Chwee Tat’s paper on PI(4)P and Myo II in NSC polarity was out in @eLife earlier this year. elifesciences.org/articles/3…
Vibrator and PI4KIIIα govern neuroblast polarity by anchoring non-muscle myosin II

Vibrator and PI4KIIIα govern neuroblast polarity by anchoring non-muscle myosin II

Vibrator and PI4KIIIα that stimulate the synthesis of PI(4)P anchor non-muscle myosin II RLC (Sqh) to the plasma membrane and conversely Sqh associates with PI(4)P and facilitates its membrane...

elifesciences.org
Thomas Brody (@interactivefly) profile pictureThomas Brody@interactivefly25 Oct 2018
Hsp83/Hsp90 physically associates with Insulin receptor to promote neural stem cell reactivation. Open access in Stem Cell Reports: ncbi.nlm.nih.gov/pmc/article…
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Wow! CRISPR-Cas9 Screens Reveal Genes Regulating a G0-like State in Human Neural Progenitors.
bioRxiv Cell Biology (@biorxiv_cellbio) profile picturebioRxiv Cell Biology@biorxiv_cellbio17 Oct 2018
CRISPR-Cas9 Screens Reveal Genes Regulating a G0-like State in Human Neural Progenitors biorxiv.org/cgi/content/shor… #biorxiv_cellbio
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