Psychiatry PGY-1 @UCIrvineHealth | MD/PhD from UCI MSTP | early life adversity, reward circuits, addiction | sclevis on 🦋
Joined August 2019
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Sophia Levis, MD, PhD retweeted
Stress can either forge resilience or trigger depression. A captivating @Nature study reveals that a hippocampal-amygdala pathway encodes the resilience trait, and stimulating this circuit can even reverse stress-induced depression.
Sophia Levis, MD, PhD retweeted
JUST dropped! Neuron Review on the Evolving Neurobiology of Early-life stress with @mtbirnie . Where is our field? what are our challenges? Where and how are we going? 300 refs. cell.com/neuron/fulltext/S08… @UCIrvine @UCIMedSchool
Sophia Levis, MD, PhD retweeted
Dear colleagues & friends: In light of recent announcements, the search committees and I wanted to reassure potential candidates that the faculty search (three faculty openings) for our new UCI Depression Institute continues as planned. Please RT
Sophia Levis, MD, PhD retweeted
1/9: Delighted to announce that our faculty cluster hire for the newly established Noel Drury, M.D. Institute for Translational Depression Discoveries at UC Irvine is now live. The submission deadline is April 9, 2025.
Sophia Levis, MD, PhD retweeted
No, despite appearances, these are NOT my frying neurons, but axon projections of CRH/GABA expressing BLA neurons to dorsomedial striatum. Paper dropping soon. By the amazing yuncai . it is #FluorescenceFriday somewhere
Happy to share that the final chapter of my PhD is now online as part of a special issue of Addiction Neuroscience on stress and addiction! We explore the link between adversity, addiction, and the role of delta opioid receptors in mediating that link:
sciencedirect.com/science/ar…
Sophia Levis, MD, PhD retweeted
A rat model of operant negative reinforcement in opioid-dependent males and females
link.springer.com/article/10…
Sophia Levis, MD, PhD retweeted
📢Excited to share our new pub in Dev Psychobiology! with @prof_suyeongkim
onlinelibrary.wiley.com/doi/… We examine how neighborhood and household contexts influence hair cortisol levels—a biomarker of chronic stress—in Mexican-origin adolescents from low-income immigrant families.
Sophia Levis, MD, PhD retweeted
Join us in congratulating the 2024 ACNP Travel Award Class! bit.ly/46GyJK1 @AArulpragasam @estef_azevedo @igorbandeira @ABoscutti @CarinaSBrown @brendacabreram @therealRYC @SSebastianChoi @not_kristie @ANeurogirl @PashaDavoudian @KevinFDowling @ScientificRuvvy @CassieLHendrix @deedsou @mkvarta @sj_lamontagne @lujanpema @carolinamak15 @PeteManza @DavidJMarcus2 @Molas__S
Sophia Levis, MD, PhD retweeted
New paper out in @NatureNeuro!
Collaborating with several labs, we developed genetically encoded biosensors to track opioid pharmacology in the brain & provide powerful new tools for dissecting complex circuit-specific dynamics 🔧🧠
nature.com/articles/s41593-0…
Sophia Levis, MD, PhD retweeted
🚨 NEW @npp_journal paper alert 🚨
Barbano, Morales, & team report that VTA glutamatergic projections to the nucleus accumbens suppress psychostimulant-seeking behavior in 🐭
nature.com/articles/s41386-0…
Sophia Levis, MD, PhD retweeted
Don't forget to register for @EurBehavPharm - early bird prices end July 12 (this Friday!) ⏳
The #EBPS2024 lineup is 🔥🔥 so you definitely don't want to miss this one! 👇
Register & more info here: ebps2024.azuleon.org/
Sophia Levis, MD, PhD retweeted
So happy to say that I officially have my first publication🥳 Thank you to @DemaestriC and congratulations on another amazing paper🌟 Check it out: nature.com/articles/s41467-0…
Sophia Levis, MD, PhD retweeted
New paper out! 🐁🐀🧠
We show that inflammatory responses can be socially transmitted among conspecifics, especially in the postnatal period.
@BrainBehavImm @CSAN_LiU
Thanks to all the team 😄
doi.org/10.1016/j.bbi.…
Sophia Levis, MD, PhD retweeted
I'm delighted to share my grad student Vini's publication! doi.org/10.1016/j.pneurobio.… (open access to all) One of the first major publications to come from my lab.
He started off with a very basic question: how do neurons **sense** injury to their dendrites?
Sophia Levis, MD, PhD retweeted
🚨 new opinion piece alert 🚨
@Marie_Eikemo @GuroLoseth & I revisit an old dataset - inspired by @DrKellyDunn’s super thorough opioid drug effects study
We argue that the variability is meaningful & that the field needs to pool data into a consortium 📊
onlinelibrary.wiley.com/doi/…
Sophia Levis, MD, PhD retweeted
A master regulator of opioid reward in the ventral prefrontal cortex | Science science.org/doi/10.1126/scie…
