Professor & COS Faculty Fellow, Mito Uncouplers, Sph Kinase & S1P transport inhibitors. B & Si Methods. Co-Fndr: ContinuumBio, S1P Therapeutics, UncouplerBio
Blacksburg, VA
Joined March 2015
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Congrats to @santoslabVT @MatthewDupuis and @Roman for their work on invasive fungal infections.
HTS from @SeleemLab ID our Spns2 inhibitors. MedChem led to SSD2032594, a fungicidal MIC of 1 µg/mL vs C. auris and C. neoformans. @VTChemDept @VT_Science
doi.org/10.1021/acs.jmedchem…
Webster Santos retweeted
Researchers have identified a key protein that may help failing hearts regain function, offering new insight into why some hearts recover while others do not. 🫀
🔗: go.vt.edu/upS4b
ALT Junco Warren (at center), an assistant professor at the Fralin Biomedical Research Institute at VTC, helped lead a study published in the Journal of the American Heart Association that sheds light on the process of recovery from heart failure. Members of her lab including (from left) Audrey Korte, Mysha Alabbi, Alexey Zaitsev, Samia Tasneem, Karthi Sreedevi, and Abigail Doku study the mechanisms underlying metabolic reprogramming in the failing heart.
Congrats to @santoslabVT @Matthew_23232 for winning the inaugural David Kingston graduate fellowship in chemistry & Fall’26 graduate school doctoral assistantship award in chemistry. Woohoo 🎉!
Webster Santos retweeted
Getting the dose on new research💊
The Center for Drug Discovery recently held a poster session, where researchers showcased their innovative findings!🔬🙌
ALT Groups of girls talk with one another in front of their posters.
ALT Three guys laugh, smile, and talk with one another in front of posters.
ALT A woman shares her research poster with others.
ALT A bird's eye view of the event, showing people walking around and talking with one another about their posters.
Webster Santos retweeted
Virginia Tech was named one of the country’s top universities for invention patents by @AcadofInventors.🔬🙌
Among these patentors is @VTChemDept professor Webster Santos (@santoslabVT), who works in @drugdisc_vt to develop novel drug compounds.
bit.ly/4bLBfS0 – at Blacksburg, VA
Webster Santos retweeted
Very excited to join @LcsoLab & @HariGroupIISc at the Cheminar on Strain-Release Chemistry ⚡️⚡️⚡️ cassyni.com/events/P3TyBNeUd…
Webster Santos retweeted
Catalytic Stereospecific Construction of Aminocyclopropanes from β-Boryl Amides | Journal of the American Chemical Society @BostonCollege pubs.acs.org/doi/10.1021/jac…
Webster Santos retweeted
Matthew Dupuis, a graduate student in the @santoslabVT, competed in the Nutshell Games!
Listen to his pitch on his medicinal chemistry research that focuses on treating highly resistant, deadly fungal infections 👉 youtube.com/watch?v=kdyseDMe…
#vtchem #commscivt
Webster Santos retweeted
Catalytic Stereoselective Silyl- and Boraformylations: Charting a Challenging Road Ahead (@angew_chem): onlinelibrary.wiley.com/doi/….
Webster Santos retweeted
Stable BF₂ Boracycles as Versatile Reagents for Selective Ortho C–H Functionalization (@ChemRxiv): chemrxiv.org/engage/chemrxiv… (@sundenlab, @GaneshDFB).
Webster Santos retweeted
Spin Delocalization of Nitrile-Ligated Diarylboryl Radicals Enables Photochemical Boracycle Synthesis via N-Borylimidoyl Radicals (@JuntaoYe): pubs.acs.org/doi/10.1021/jac… (@J_A_C_S).
Webster Santos retweeted
Persistent Boryl Radicals as Highly Reducing Photoredox Catalysts for Debrominative Borylations (@J_A_C_S): pubs.acs.org/doi/10.1021/jac… (@AggarwalLab).
Webster Santos retweeted
Xanthopinacol Boronate: A Robust, Photochemically Assembled and Cleavable Boronic Ester for Orthogonal Chemistry (@HallBoronLab): onlinelibrary.wiley.com/doi/… (@angew_chem).
Webster Santos retweeted
Mapping Boryl Radical Properties and Reactivity Using Machine Learning: the B-rad and React-B-rad maps (@ChemRxiv): chemrxiv.org/engage/chemrxiv….
Webster Santos retweeted
Synthesis of gem-di(boryl)cyclopropanes from non-activated olefins via Mn-photocatalyzed atom transfer radical addition (@ChemicalScience): pubs.rsc.org/en/content/arti….
Webster Santos retweeted
Boronate Formation-Triggered Azide–Alkyne Cycloaddition (@JOC_OL): pubs.acs.org/doi/10.1021/acs… (@yuukiwomanabu).
Webster Santos retweeted
The impressive surge of recent papers on BCB chemistry is evident in this review 📚: Catalytic Asymmetric Strategies for Bicyclo[1.1.0]butane Transformations: Advances and Applications | CCS Chemistry chinesechemsoc.org/doi/10.31…
Congrats to @santoslabVT PhD #31: Dr. Joseph Quinlan. He is our antivirulence/antiobesity guru targeting PilB and mitochondria. #medchem 🙌💪 @VTChemDept @VT_Science @FralinLifeSci
Congratulations to our 2025 VT Center for Drug Discovery @drugdisc_vt poster session winners: Darwin Gomez (@SEE_adrian_figg), Emily Krinos (@santoslabVT) & Ahmed Abouelkhair (@SeleemLab). 🙌 @FralinLifeSci @VT_Science
