Samuel Corless retweeted
Calling all aspiring centromere biologists! Rae Brown (Straight Lab) and I will co-chair the GRS for Centromere Biology, preceding the main GRC on 27th-28th July 2024. Please retweet and register before April 21st to be considered for a talk! grc.org/centromere-biology-g…
Samuel Corless retweeted
Join us at our 22nd @EdinEpigenetics Meeting
@EdinburghUni Network #research #epigenetics #chromatin #Edinburgh
Samuel Corless retweeted
Warm welcome to our new Principal Investigator Dr Nezha Benabdallah @NsBenab👍! Nezha leads the Chromatin Regulators in Cancer research group. Her scientific interests focus on sarcoma research and chromatin biology. Read more on our website:
ed.ac.uk/cancer-centre/news-…
Samuel Corless retweeted
Several roadblocks must be overcome to make molecular biology more sustainable, but @GreenLabGuy @ucl argues that we must treat sustainability like we do health and safety in the lab—as a necessity.
ALT "Currently we have de-incentivized sustainability. Not only are many sustainability initiatives entirely voluntary, many scientists don’t see how their work impacts energy consumption, carbon emissions, or often even finances. We need to review these systems if we want sustainability to be fully integrated, just like health and safety is today." - Martin Farley, University College London
Samuel Corless retweeted
a while ago I posed this question...
1/
Centromere biologists take note!
Improve your CUT&RUNs with
The CUT&RUN Suspect List of problematic regions of the genome
genomebiology.biomedcentral.…
by @AnnaNordin96 w/ @GianlucaZamba @ppagella86
now @GenomeBiology
❗️IMPORTANT: the Suspect Lists content did not change from the previous release @biorxivpreprint
This study is amazing! I always wondered if the role of nucleosomes was more about DNA supercoils than 'packaging', these different topologies are a nice hint in that direction. biorxiv.org/content/10.1101/…
Did you know JQ1 directly targets BRD4 at centromeres? #Epigenetics is more than gene regulation! To find out more read our updated BioRxiv biorxiv.org/content/10.1101/…
Samuel Corless retweeted
The bromodomain inhibitor JQ1 is a molecular glue targeting centromeres biorxiv.org/cgi/content/shor… #bioRxiv
Thanks chromatin community! We’ve been digging around in your repetitive DNA (>40,000 ChIP-seq samples) and have discovered a totally unexpected role for BRD4 and JQ1 at centromeres. Very happy to share our preprint. biorxiv.org/content/10.1101/…
Samuel Corless retweeted
New research in Science presents a synapse-by-synapse map of an insect’s brain, representing a valuable resource for future experimental and theoretical studies of neural circuits and brain function. scim.ag/1RU
Samuel Corless retweeted
Biophysics question:
In transcription, RNApol generates positive supercoils ahead of it and negative ones behind it
WHY?
Why doesn’t RNApol instead simply track 1 strand of the duplex, follow its helical twist along the duplex, and thus rotate without any supercoil generation?
