@rhyscienceallan

Scientist @wehi_research, fascinated by the DNA circuitry of the immune system

 Melbourne, Victoria
wehi.edu.au/people/rhys-allan
Joined August 2016
  • Tweets4.9K
  • Following806
  • Followers1.4K
241Media
📣We are excited to announce the July edition of the GOA seminar series will be presented by Siyuan Wang from Yale. Please register below to join us on the 30th! unimelb.zoom.us/webinar/regi…
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💥💥💥🚨🚨🚨Join us tomorrow for the first seminar of 2025👇👇
Genome Organisation Australia@GenomeOrgAus5 Mar 2025
Please join us for the first GOA seminar of 2025 unimelb.zoom.us/webinar/regi…
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Congratulations @HarshiniChandr8 💐 Using human neurons homozygously-engineered with familial AD mutations, she found a role for miswired promoter-enhancer multi-loops in dysregulated excitatory and inhibitory gene expression programs BioRxiv: doi.org/10.1101/2024.02.27.5…
Genome Organisation Australia@GenomeOrgAus25 Nov 2024
We are excited to announce the winner of the GOA Young TAD for 2024 is @HarshiniChandr8 🏆🥇🏅 Congratulations to Harshini and also to the other finalists! The 3D genome field is in great shape with so many innovative young scientists!
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Congratulations Harshini on a great presentation and an exciting project!
Genome Organisation Australia@GenomeOrgAus25 Nov 2024
We are excited to announce the winner of the GOA Young TAD for 2024 is @HarshiniChandr8 🏆🥇🏅 Congratulations to Harshini and also to the other finalists! The 3D genome field is in great shape with so many innovative young scientists!
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We are excited to announce the winner of the GOA Young TAD for 2024 is @HarshiniChandr8 🏆🥇🏅 Congratulations to Harshini and also to the other finalists! The 3D genome field is in great shape with so many innovative young scientists!
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Ready for #AEpiA2024? The full conference programme and key details are live! Explore everything you need to know here: aepia.org.au/conferences
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Incredibly excited that our paper linking single molecule states of TF binding to gene expression using quantitative thermodynamic models is out in Nature today. An amazing collaboration with the Bintu Lab. Congrats to Ben, Michaela, and Julia! nature.com/articles/s41586-0…

Single-molecule states link transcription factor binding to gene expression

Nature - A study uses single-molecule footprinting to measure protein occupancy at regulatory elements on individual molecules in human cells and describes how different properties of transcription...

nature.com
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Intravenous iron given in the second trimester of pregnancy impacts on anaemia and iron-deficiency all the way up to 6-12 months postpartum! Another stellar collaboration between @WEHI_research and @TRUECOM1 - The Lancet Global Health thelancet.com/journals/langl…

Postpartum maternal and infant haematological effects of second-trimester ferric carboxymaltose...

Ferric carboxymaltose treatment in the second trimester protected women from postpartum anaemia and iron deficiency but did not affect infant haematological or iron status.

thelancet.com
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Sharing our latest work @JExpMed! We've uncovered that P2RX7 regulates unconventional T cells selectively, particularly subsets that co-produce IFN-γ & IL-4. Hoping this helps more discoveries in the role of these innate-like cells, using inhibitors from the P2RX7/ARTC2 field!
Rockefeller U. Press@RockUPress19 Nov 2024
In @JExpMed, Xu, @_fernace et al. @TheDohertyInst reveal that the ARTC2–P2RX7 regulatory axis is a key modulator of unconventional T-cell survival, showing how this pathway selectively influences innate-like, IFN-γ and IL-4 co-producing T cells. hubs.la/Q02YMvMt0
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Excited to share our @oncogenejournal review "Breathing new insights into the role of mutant p53 in lung cancer" ✍️ by 🌟PhD student Tianwei Chen - co-supervised with Gemma Kelly & Andreas Strasser. nature.com/articles/s41388-0…. 😎 research coming soon! 👇

Breathing new insights into the role of mutant p53 in lung cancer

Oncogene - Breathing new insights into the role of mutant p53 in lung cancer

nature.com
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Pleased to share that our #earlyAIR cross-tissue, age-specific, #flowcytometry reference of immune cells from five tissues of the pediatric #airway is now published in @jacionline. jacionline.org/article/S0091… @cziscience @MCRI_for_kids @UniMelbMDHS @RCHMelbourne
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Rhys Allan retweeted
Marty Yang@MartyYang15 Nov 2024
Ecstatic to share the first story from my post-doc, co-led with Megan Ostrowski, out now in final form (cell.com/cell/fulltext/S0092…)!

The single-molecule accessibility landscape of newly replicated mammalian chromatin

By developing a long-read sequencing method to simultaneously map replication status and protein-DNA contacts in cells, Ostrowski, Yang, et al. show that newly replicated chromatin is enriched for...

cell.com
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🤯 It’s such a pleasure to host this session which will feature young TADs from all over the globe! Who will be the 4th GOA Young TAD? Please register to join us👇
Genome Organisation Australia@GenomeOrgAus15 Nov 2024
🚨 Please register here to join us to support these amazing young scientists unimelb.zoom.us/webinar/regi…
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Just ICYMI, earlybird rego, oral abstract submissions and award applications for #lornegenome25 have been extended to Friday 15 Nov 2024! The @GenomeConf have been busily assembling a great program and we can't wait to see you in Lorne in February 2025! lornegenome.org
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Check out our latest from @WEHI_research A joint effort with James Vince’s lab and our RMH colleagues. Super proud of this epic built on ~1100 western blots. Full credit to the leads, Jiyi Pang and Aysha Al-Ani, our collaborators, and my coconspirators including @AndreSamson15
bioRxiv Cell Biology@biorxiv_cellbio13 Nov 2024
A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease biorxiv.org/cgi/content/shor… #biorxiv_cellbio
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Opportunity for a bioinformatician to join the lab @PeterMacRes to help us identify new Immunotherapies. Please reach out for further details. Ad is for a post doc but research assistants & PhD students considered…we just want the best fit. 💻 🧬 careers.petermac.org/job/MEL…

Postdoctoral Researcher - Beavis and Waithman labs

Postdoctoral Researcher - Beavis and Waithman labs

careers.petermac.org
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Very proud & excited to be socialising our preprint uncovering new mechanisms of epithelial cell death in IBD! Massive 4-year collab across @WEHI_research & @RMH. Big thanks to the patients involved in this study and support from @NHMRC & @KR_Foundation biorxiv.org/content/10.1101/…

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

Inflammatory bowel disease (IBD) is a chronic condition caused by altered cytokine signaling, maladaptive immunity, dysbiosis, and intestinal barrier dysfunction. Patients with IBD receive therapy to...

biorxiv.org
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We have 15 PhD positions available as part of the DANIO-ReCODE MSCA DN. Great opportunity for anyone interested in developmental biology, regeneration, genomics, and computational sciences. For project descriptions and how to apply, check: euraxess.ec.europa.eu/jobs/2…
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Heterozygous mutations in the MYST family histone lysine acetyltransferase, KAT6B, cause intellectual disability disorders. This study identifies the histone and gene targets of KAT6B which include SOX2, a master regulator of neural stem and progenitor cells. @WEHI_research life-science-alliance.org/co…
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We are excited to recruit a PhD student for 2025 @CCB_Research in Adelaide to tackle immune dysfunction in head and neck cancer. Please share and apply: unisa.edu.au/research/degree…
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