realArnoldLab retweeted
We are looking for a new colleague :)
Please, spread the word!
📢Job Alert! The Faculty of #Biology of the @UniFreiburg is seeking for a researcher with a competitive, internationally visible profile in #ChemicalBiology focusing on #BiologicalSignallinResearch.
Join us and apply by 28 February, 25!
More info: uni-freiburg.de/stellenangeb…
ALT Sharepic calling for a professorship (W3) in Integrative Signalling Research at the Faculty of Biology at the University of Freiburg, Deadline 28 February 2025.
realArnoldLab retweeted
Finally out in print! Check out our study on multiparameter imaging to reveal cancer cell state-dependent crosstalk with stroma that determines patient outcome 👇
In the latest issue! Multiparameter imaging reveals clinically relevant cancer cell-stroma interaction dynamics in head and neck cancer dlvr.it/TGmjZ8
Happy to share latest work from the Lab by lead author Chiara Schröder, out in DevCell: global enhancer remodeling giving competence for mesoderm/endoderm differentiation by co-workers EOMES and SWI/SNF. Transcription comes later! So, EOMES is not a TF, but a chromatin regulator!
realArnoldLab retweeted
I am very proud of Yasmine from the lab for winning a poster prize at the #GfE2024 organized by the German and Dutch societies for developmental biology for her work on Hes1 dynamics in the embryonic tail. Congratulations!
Here are the five poster prize winners of the #GfE2024 in alphabetic order: Vanessa Disela, Yasmine el Azhar, Olga Jarosinska, Laura Klink, Barbara Ohlebusch. Congratulations to you!
realArnoldLab retweeted
Please RT: Job opportunity!
The Faculty of Medicine at the University of Freiburg, Germany, invites applications for a Full Professorship for Biochemistry and Molecular Biology.
@UniFreiburg @Uniklinik_Fr
med.uni-freiburg.de/en/admin…
ALT Screenshot of the job posting that is linked in the twitter post. The title of the professorship is Full Professorship (W3) of Biochemistry and Molecular Biology (Succession of Prof. Dr. Nikolaus Pfanner)
realArnoldLab retweeted
WRT the recent interest in TbxT, aka #Brachyury, & all kind of tails, nice historical perspective on this most iconic gene in the history of #DevBio shorturl.at/lEK57. Below, heroes of Brachyury (Fig.2 in ref ) + B. Herrmann, who cloned the gene &, of course, the T/+ mouse
Happy to share Tanja‘s new preprint: looking@transcription from quite a different angle: basal TFIID, IDRs and splicing.
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realArnoldLab retweeted
TBX3 is essential to establish the posterior boundary of anterior genes and up-regulate posterior genes with HAND2 during onset of limb bud development dlvr.it/T2FCW2
realArnoldLab retweeted
"....Mouse embryos in diapause are sustained by using lipids as primary energy...." source nature.com/articles/s41556-0… by @bulutkarslioglu and colleagues. also another cool work by Aydan Bulut-Karslioglu and colleagues @NRivron @NiakanLab using this to control dev timing in 🕺🏃♀️human biorxiv.org/content/10.1101/…
realArnoldLab retweeted
We provide further evidence for the downregulation of NOGGIN by pSMAD, as predicted by our simulations, and detail the early antiphasic behavior of GDF5 and pSMAD that result from a self-organizing Turing system that drives joint initiation in developing digits of amniotes... 2/3
realArnoldLab retweeted
📢 Marc Timmers of Universitätsklinikum Freiburg will speak at our #DahlemColloquium!
📜 Basal transcription factor TFIID in neurodevelopment and neurodegeneration
📆 11. DEC, 11:00 AM (CET)
📍 MPIMG , Berlin
🔗 molgen.mpg.de/events/36185/3…
realArnoldLab retweeted
Very curious if anyone guessed this 😁 Our 2023 Method of the Year is methods for modeling development (aka embryoids)!!!! Some amazing things happening in this space enabling our understanding of the earliest stages of embryogenesis and beyond. Please enjoy the issue!
It's that time of year!! 🎉We are so excited to announce our 2023 pick for Nature Methods' Method of the Year: methods for modeling development. Read the Editorial to find out why we chose this as our pick. #moty2023
nature.com/articles/s41592-0…
realArnoldLab retweeted
Two back-to-back manuscripts on metabolic control of germ layers using gastruloids/stembryos
tinyurl.com/576pzzy2 by @KStapornwongkul in @LabTrivedi & @EbisuyaMiki
and tinyurl.com/43e6x7su in @jvveenvliet!
An exciting time for metabolism and in vitro models of development!
realArnoldLab retweeted
The modularity/robustness of #gastruloids to explore rltnshp between #metabolism/#CellFate; 3 #preprints
@teamstembryo @jvveenvliet: shorturl.at/jptDE
@KStapornwongkul @LabTrivedi shorturl.at/sxBFL
earlier from @dd_chaitanya @BenSteventon2 shorturl.at/aozD4
realArnoldLab retweeted
Ever considered that the loss of your favorite epigenetic factor might impact gene expression in an allele-specific manner? Our new study shows allele-specific gene regulation by the chromatin regulator MSL2.nature.com/articles/s41586-0…
realArnoldLab retweeted
🚨 The lab of @AsifaAkhtar1 uncovered in @nature a mechanism that safeguards the biallelic expression of haploinsufficient genes.
The epigenetic regulator MSL2 acts as an “anti-monoallelic” factor that maintains biallelic gene dosage. This discovery not only reveals a communication system between parental alleles but also points to potential therapeutic strategies for diseases associated with haploinsufficient genes.
Congratulations to @sun_yidan, Meike Wiese & @raedhmadi 🥳
Press release: ie-freiburg.mpg.de/5808498/n…
Paper: nature.com/articles/s41586-0…
realArnoldLab retweeted
Super happy that our#MechanoFate🐸 project received #ERCCoG funding! Huge thanks to my incredible team, friends, and colleagues for their invaluable help, as well as to the reviewers, and the panel. Exciting time ahead! @UCPH_health @UCPH_reNEW @reNEW_Global
Congratulations @ksedzinski from @novonordiskfond Center for #stemcellmedicine, at @UCPH_health for being awarded an @ERC_Research grant to explore how mechanical forces coordinate the development of mucociliary epithelium > shorturl.at/lqD18
realArnoldLab retweeted
Congratulations to CIBSS member Peter Walentek @WalentekLab for being awarded a @dfg_public #Heisenberg Fellowship for his research on mucociliary epithelia!👏
➡️cibss.uni-freiburg.de/news/w…
