Higher Specialty Trainee in Diabetes & Endocrinology
Liverpool, England
Joined September 2018
- Tweets88
- Following97
- Followers38
- Likes16.9K
Prethivan retweeted
Evaluation of Current Screening Thresholds for the Detection of Primary Aldosteronism
ahajournals.org/doi/10.1161/…
Prethivan retweeted
Long-term cardiac effects of #adrenalectomy versus surveillance in mild cortisol excess: 5-year results from the prospective ITACA study by Dario De Alcubierre et al
EJE Volume 194, Issue 2, February 2026
Open access 👉 doi.org/10.1093/ejendo/lvag0…
#endocrinology #MACS #adrenal
Prethivan retweeted
REVIEW: Subtyping of Primary Aldosteronism in Partial Adrenal Vein Sampling: The Relative Aldosterone Secretion Index
ahajrnls.org/4f53P3F
PA exist in a continuum.Prevalence of PA among pts with low renin HTN is significantly higher than other causes.MRA is very helpful in reducing complication rate among low renin HTN pts.These pts will very likely have PA in the future/it's just that we've not diagnosed them yet. – at Birkenhead, England
Low-renin hypertension in incidental adrenal adenomas and response to aldosterone-targeted therapy: a prospective study @renebaudrand @ThomasUslar
authors.elsevier.com/c/1nLNb…
Prethivan retweeted
Primary Aldosteronism
nature.com/articles/s41572-0…
Prethivan retweeted
Low-renin hypertension in incidental adrenal adenomas and response to aldosterone-targeted therapy: a prospective study @renebaudrand @ThomasUslar
authors.elsevier.com/c/1nLNb…
Prethivan retweeted
Evaluating the impact of adrenalectomy and mineralocorticoid receptor antagonists for primary aldosteronism on left ventricular remodeling: a systematic review and meta-analysis by Yu-Ching Chang @ChengHsuanTsai et al 👉 doi.org/10.1093/ejendo/lvaf2…
Prethivan retweeted
REVIEW: Emerging Medical Therapies for Primary Aldosteronism
ahajrnls.org/42LtJlZ
Prethivan retweeted
REVIEWER: Aldosterone and the Mineralocorticoid Receptor in Atrial Fibrillation
ahajrnls.org/4n3bDWb
Existing models for PPGL use metadrenalines as binary-elevated or not for prognostication. But we explored the role of quantitative metadrenaline burden. Excited to receive @TheEndoSociety Outstanding Abstract Award! Will be presenting at ENDO 2026 June 13, 1:45 PM :)
#ENDO2026 – at Wallasey, England
Outstanding Abstract Award Winners | We are pleased to announce our cohort of outstanding abstract awardees for ENDO 2026. View this year's winners: bit.ly/4sZ1mvf #ENDO2026 #endocrinology
Prethivan retweeted
COMMENTARY: Beyond Spironolactone: Does Next Generation of Aldosterone Blockade Add Value?
ahajrnls.org/3OFUXXZ
Prethivan retweeted
🫀 Don’t stop spironolactone just because eGFR dips.
TOPCAT Americas analysis (1,648 HFpEF patients):
• 26% had early acute eGFR decrease ≥15% — and it was adversely prognostic
• Early eGFR dip → HR 3.53 for sustained renal decline/ESKD/renal death
• Yet spironolactone consistently reduced CV death, HF hospitalization & aborted cardiac arrest vs. placebo (P-interaction = 0.64)
The CV benefit persisted regardless of early eGFR change.
An acute eGFR dip after MRA initiation should not automatically trigger discontinuation.
#HFpEF #Cardiology #HeartFailure #MedTwitter
Prethivan retweeted
📢 New multicenter collaboration
🧬 Metastatic paragangliomas & pheochromocytomas
📊 Response & survival patterns
🤝 Two Spanish centers
Now published in Journal of Neuroendocrinology (JNE) 📖
Science moves forward together 💙 @HospitalLaFe @VHIO @vallhebron @PheoPara @APheipas
Prethivan retweeted
🧬 Advanced ACC: new prognostic model (ENSAT)
📊 Multicenter cohort (n=418)
🔑 Key factors
• Tumor burden
• Cortisol excess
• ECOG-PS
• NLR ≥5
📈 ENSAT Risk Score
➡️ Score >2 = poor prognosis
➡️ Predicts OS, TTP & treatment response
🔗 doi.org/10.1093/ejendo/lvag0…
Prethivan retweeted
🚨📅 SAVE THE DATE! Our @unibirmingham @unibirm_CMH Birmingham Adrenal Tumour Masterclass will be back on 12/09/2026.
Registrations opening soon!
ℹ️ Topic: secondary #hypertension & primary aldosteronism #primaryaldo #adrenal
🔗birmingham.ac.uk/study/short…
Grateful to be selected for the Early Career Forum Award by the @TheEndoSociety. Looking forward to the upcoming meeting ! :)
#ENDO2026 – at Wallasey, England
Congratulations to our Early Career Forum program winners. Our awardees will attend ENDO 2026 and participate in a unique workshop to connect them with experts in the field. View our awardees: bit.ly/3mDt8RR #ENDO2026 #endocrinology
Our study has been accepted as a rapid-fire presentation at ENDO 2026 Conference!
“Quantitative Metadrenaline Burden and Tumour Characteristics Predict Prognosis in PPGL: A 12-Year Single Centre Cohort Study.”
Looking forward to presenting our findings :)
#ENDO2026 – at Wallasey, England
Honored to share our work in the Adrenal Network session at #SfEBES2026, on the novel HISTAR score-integrating CYP11B2 immunohistochemistry with clinical predictors to enhance cure prediction post adrenalectomy in primary aldosteronism. Grateful for the engaging discussion ! – at Harrogate, England
