@oparent41

PhD candidate - Integrated Program in Neuroscience @IPNMcGill - Centre d'imagerie Cérébral @DouglasResearch

 Montréal, Québec
scholar.google.com/citations?user=bfEmYpEAAAAJ&hl=en
Joined August 2015
  • Tweets175
  • Following558
  • Followers210
20Media
New paper “Characterizing spatiotemporal white matter hyperintensity pathophysiology in vivo to disentangle vascular and neurodegenerative contributions” out in Nature Communications! doi.org/10.1038/s41467-026-7…

Characterizing spatiotemporal white matter hyperintensity pathophysiology in vivo to disentangle...

Nature Communications - Using advanced MRI modeling, this study found distinct spatial and pathophysiological signatures in vascular- and neurodegeneration-related white matter hyperintensities,...

nature.com
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Olivier Parent retweeted
Gabriel A. Devenyi@gadevenyiSep 8
Out in Nature Methods. Most brain-imaging figures hide everything below threshold. We argue for transparent thresholding: keep significant clusters opaque, fade the rest. Same highlights, more context. Now in AFNI, FSLeyes, NiiVue, RMINC and more. doi.org/10.1038/s41592-026-0…
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New paper in Imaging Neuroscience by Vikram Nathan, M. Mallar Chakravarty, et al: Experimental quality control induces changes in Allen mouse brain connectomes doi.org/10.1162/IMAG.a.1310
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I'm proud to share this work led from the @DouglasResearch and the @IPNMcGill and funded by the @AlzCanada and the @FRQS1. Special thanks to my supervisors, @mallarchkrvrty1 and @DadarMahsa, who showed great patience every time I added an analysis to this project in the last 4y!
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Huge thanks to co-authors and collaborators @zklsmr Sophia Osborne @AurelieBussy @manuelacostan13 @JeremieFouquet Daniela Quesada Alexandre Pastor-Bernier Alfonso Fajardo Valdez Alexa Pichet-Binette Ann McQuarrie Josefina Maranzano @gadevenyi Christopher Steele @sylv_villeneuve
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Alfie Wearn@AlfieWearnMar 1
We recently published a paper in PNAS, showing microstructural changes to the hippocampus in aging and presymptomatic Alzheimer's disease - in humans, in vivo. We continue to show the value of structural MRI beyond just measuring large-scale atrophy! ow.ly/1NvV50XkXnX

Quantitative MRI of the hippocampus reveals microstructural trajectories of aging and Alzheimer’s...

Hippocampal degeneration is a feature of both normal aging and Alzheimer’s disease (AD). Prior to macroscopic degeneration, microstructural changes...

pnas.org
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Olivier Parent retweeted
Gabriel A. Devenyi@gadevenyiFeb 27
Do you use the Allen Institute's Mouse Gene data? Take a look at this in-depth quality control study biorxiv.org/content/10.64898…
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Carolina Tropini, PhD@CTropiniFeb 13
CIHR funding rate: 13.6%. Early 2000s: 30%+. Canada’s new $1.7B Impact+ program recruits talent — but without increased Tri-Council base funding, we risk further strain on an already stretched system. We’re calling for $1B over 5 years. Support here: tinyurl.com/33c5av46

Letter to Canadian Government to Increase Research Funding - 202602

Update 05/26/2026 Dear colleagues, A quick update, we received a response from Minister Mélanie Joly regarding the letter many of you signed on research funding and the Impact+ initiative, conversa...

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Olivier Parent@oparent4112 Jun 2025
After 3 years of "just one more analysis", happy to share our preprint! Building on previous post-mortem findings of non-vascular WMHs, we identified a specific signature of neurodegenerative WMHs in vivo using microstructural MRI and normative modeling doi.org/10.1101/2025.06.10.2…
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After 3 years of "just one more analysis", happy to share our preprint! Building on previous post-mortem findings of non-vascular WMHs, we identified a specific signature of neurodegenerative WMHs in vivo using microstructural MRI and normative modeling doi.org/10.1101/2025.06.10.2…
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Huge thanks to all who have supported and helped this project @zklsmr @AurelieBussy @JeremieFouquet @gadevenyi @sylv_villeneuve @DadarMahsa @mallarchkrvrty1 ...
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... and twitter-less Sophia Osborne, Manuela Costantino, Daniela Quesada, Alexandre Pastor-Bernier, Alfonso Fajardo-Valdez, Alexa Pichet-Binette, Ann McQuarrie, Josefina Maranzano, Christopher Steele
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If you’re into rodent fMRI, you should definitely check this work led by Mila Urosevic! A great resource for anyone developing an acquisition protocol and who wants to improve measurements of resting-state networks.
bioRxiv Neuroscience@biorxiv_neursci20 May 2025
Evidence-based guidelines for improving network detectability in rodent fMRI biorxiv.org/content/10.1101/… #biorxiv_neursci

Evidence-based guidelines for improving network detectability in rodent fMRI

Mouse resting-state functional magnetic resonance imaging (rs-fMRI) is an increasingly popular tool for probing brain activity under experimental manipulations; however, there remains considerable...

biorxiv.org
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My paper introducing my longitudinal DBM pipeline and examining the ultimate sensitivity of it in human data is now published at ApertureNeuro! apertureneuro.org/article/13…

Longitudinal deformation-based morphometry pipeline to study neuroanatomical differences in...

By Jurgen Germann, Flavia Venetucci Gouveia & 2 more. Here, we present a two-level DBM technique, where the Jacobian determinants are first calculated at the subject level, followed by co-registrat...

apertureneuro.org
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