@nonlinearities

Moved elsewhere

Joined July 2020
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“Data Compression Versus Signal Fidelity Tradeoff in Wired-OR Analog-to-Digital Compressive Arrays for Neural Recording” ieeexplore.ieee.org/abstract… Yan et al perform a data-driven exploration of robustness, configurability and scalability of wired-OR A/D compression ASICs for BMI
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It has been wonderful to work on this project with you! I'm looking forward to playing with these and the rest of the upgrades.
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1/Our paper @NeuroCellPress "Interpreting the retinal code for natural scenes" develops explainable AI (#XAI) to derive a SOTA deep network model of the retina and *understand* how this net captures natural scenes plus 8 seminal experiments over >2 decades sciencedirect.com/science/ar…
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They made the floating rocks
Andrew McCalip
@andrewmccalip4 Aug 2023
Meissner effect or bust: Day 8.5 We made the rocks
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Bamboos appear to move.
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If an alien visited and gave us this shape as a gift, a few months ago we might not have understood what it meant, but now we know it’s an advanced technology – at Poplar, London
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awesome work with fascinating results for RGC classification work, looking forward to diving into the details
Nayoung Jun@nayoung_jun19 Sep 2022
Why do we need SO many cell types in the retina? Efficient coding theory can begin to answer that! I am happy to announce that my new work “Efficient coding, channel capacity and the emergence of retinal mosaics” with @GregDField & @jmxpearson is accepted to #NeurIPS2022! more👇
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Embryonic retinal waves! In new study led by superstar student @CVoufo, @AndyQuaen and Ben Smith, a team led by @atiriac1, we describe waves at early stages of development – long before proper neural circuits are present in the retina. biorxiv.org/content/10.1101/…
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Impressive decoding of natural visual stimuli from responses of complete RGC populations !!
bioRxiv@biorxivpreprint20 May 2022
Maximum a posteriori natural scene reconstruction from retinal ganglion cells with deep denoiser priors biorxiv.org/cgi/content/shor… #bioRxiv
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New preprint from my lab from the Twitterless, but amazing students Sylvia Durian and Mark Agrios: biorxiv.org/content/10.1101/… Some tonically firing neurons are "bursty" while others spike more regularly. This is true in the retina as well. But why? 1/5

Mind the gap: decoding decreases in tonic firing in populations of spiking neurons

A stimulus can be encoded in a population of spiking neurons through any change in the statistics of their spike patterns. Thus, the baseline spike statistics in the absence of a stimulus can impact...

biorxiv.org
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1/ Can A.I. do our literature reviews for us? Stop everything and try elicit.org, an amazing new tool that uses large language models to answer research questions via empirical research- in the video below I ask it "Does social media negatively impact mental health?"
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This was a wonderful collaboration with @nymarklab. I learned so much about RPE. Fascinating and electrically active cells! Julia Fadjukov and @SophiaWienbar figured out how to patch them in the intact monolayer in a mouse eye!
Journal of General Physiology@JGenPhysiol11 Mar 2022
Cells in #retinalpigmentepithelium are coupled thru Cx43-based gap junctions. Fadjukov, @nymarklab @SchwartzLabNU et al show that #gapjunctions AND Cx43 #hemichannels make substantial contributions to the input resistance of these electrically active cells bit.ly/3J4CnAT
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Differential mosquito attraction to humans is associated with skin-derived carboxylic acid levels biorxiv.org/content/10.1101/…

Differential mosquito attraction to humans is associated with skin-derived carboxylic acid levels

Female Aedes aegypti mosquitoes feed on human blood, which they use to develop their eggs. It has been widely noted that some people are more attractive to mosquitoes than others, but the mechanistic...

biorxiv.org
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Excited and proud to share my postdoc work out @nature today: go.nature.com/3pscOlX. It all started as a conversation on a balcony many years ago with @zmainen on the mysteries of olfaction and spatial cognition 👃🧠🚀 Video by @Neuro_CF AV team 👉youtu.be/BunEBiU3MO0 1/n
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Tour de force by Graves et al: visualize learning at synaptic level across whole brain! Now we're getting somewhere... Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors doi.org/10.7554/eLife.66809

Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors

A knockin mouse line was made to label endogenous AMPA receptors, enabling direct observation of synaptic plasticity in behaving animals with single-synapse resolution across the entire brain.

elifesciences.org
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1/ People study medial entorhinal cortex (MEC) because of its key role in navigation and memory. In our new paper we build neural network models that explain the full diversity of neural responses in MEC. To appear as a #NeurIPS2021 Spotlight! Tweetprint below 👇🧠
bioRxiv Neuroscience@biorxiv_neursci3 Nov 2021
Explaining heterogeneity in medial entorhinal cortex with task-driven neural networks biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Efficient Inference of Sensitivity to Electrical Stimulation from Intrinsic Electrical Properties of Primate Retinal Ganglion Cells biorxiv.org/cgi/content/shor… #biorxiv_neursci
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October’s #ImageOfTheMonth is a bipolar cell (green) receiving nerve signals from cones (red dots), the cells that detect color and bright light.
Image of a bipolar cell (green) receiving nerve signals from cones (red dots), the cells that detect color and bright light. The rods (blue), or the cells that detect shadows and dim light, are not receiving those signals.

ALT Image of a bipolar cell (green) receiving nerve signals from cones (red dots), the cells that detect color and bright light. The rods (blue), or the cells that detect shadows and dim light, are not receiving those signals.

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I'm excited to see this huge effort finally published. It was a pleasure to work with Fred Rieke and two talented undergrads, Belle Liu and Arthur Hong on this project. @arthurhongTW @NatureNeuro rdcu.be/creHT nature.com/articles/s41593-0…
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