Assistant Professor @UOAofficial MD, PhD, FACS HPB Surgery / Liver Transplant / 🧬🦀🔪 @UOAofficial x @RoyalFreeNHS x @MayoClinic
Athens, Greece
Joined January 2017
- Tweets512
- Following1.4K
- Followers1.5K
- Likes3.5K
Nik Machairas retweeted
🙌BRAND NEW 🙌
Explore the future of HPB surgical education with the E-AHPBA Online Academy — expert-led webinars, interactive modules & global collaboration to advance your practice.
Read more - eahpba.org/e-ahpba-online-ac…
Nik Machairas retweeted
🧬 RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer
🎯 A milestone one in @Nature 🎯
🦠 Responders with vaccine induced t-cells have prolonged RFS compared to non responders
💉 Vaccine for PDAC not a dream anymore?!
nature.com/articles/s41586-0…
Nik Machairas retweeted
Check out our latest study on #Racial and #sex-based variations in #genomic profiling of #iCCA published in @AnnSurgOncol @SocSurgOnc
Different genetic drivers that may be targetable to treat diverse cohorts @OhioStateSurg @timpawlik @johnntanasis
link.springer.com/article/10…
Nik Machairas retweeted
Pip/Tazo is in the @WHO Watch category of the AWaRe classification and it should not be used deliberately! It’s a lazy way of treating SSI. More appropriate to tailor the treatment based on bile stenting, preop bile culture, and rectal swab colonization with MDR! @heatherevansmd
Nik Machairas retweeted
Antibiotics 💊 for prophylaxis during pancreatoduodenectomy 🙋🏻♀️ … did you change your practice?
💉 Pip/Tazobactam ⬇️ surgical site infections and major complications
New meta-analysis supporting 🇺🇸 trials just published!
👉academic.oup.com/bjsopen/art…
Nik Machairas retweeted
We express our sincere gratitude
for your attention and interest in our recently published study @BjsOpen titled "Piperacillin/tazobactam for surgical prophylaxis during pancreatoduodenectomy: a meta-analysis ." We are hopeful that the findings from this study will contribute towards enhancing the outcomes of the whipple procedure. @hollylneville @mhshospital
@imperialcollege @UChicago @uchicagosurgery @cuttingman_fung @MauroPodda2 @nmachair @RArasaradnam @FraVirdis
Piperacillin/tazobactam for surgical prophylaxis during pancreatoduodenectomy: meta-analysis
➡️doi.org/10.1093/bjsopen/zrae…
Piperacillin/tazobactam as antimicrobial prophylaxis significantly lowers the risk of postoperative surgical-site infections, major surgical complications (complications classified as Clavien–Dindo grade greater than or equal to III), clinically relevant postoperative pancreatic fistulas (grades B and C), and mortality, hence supporting the implementation of piperacillin/tazobactam for surgical prophylaxis in current practice.
👏👏👏@JayKumar_MD_PhD, Isabella Reccia, Adriano Carneiro, Mauro Podda, Francesco Virdis, Nikolaos Machairas, David Nasralla, Ramesh P Arasaradnam, Kenneth Poon, Christopher J Gannon, John J Fung, Nagy Habib, Omar Llaguna
#SoMe4Surgery #MedTwitter #SurgEd #Surgery @me4_so @for_surgery @for_surgeons @modern_surgeon @surggpt #some4hpb #some4tpl @hpb_so #PancreaticCancer #Pancreatitis @YouppiePancreas @German_PancClub @surgery_hps #PancreasClub2023 @PancreasClub @EurPancClub @P_C_E_ @dice_europe @DPCG_official @pancreatitis_nl @PanCAN #PanCANawareness
Nik Machairas retweeted
First paper from Novara @UniAvogadro
Data from #MANCTRA-1 highlight the relevance of
➡ Socioeconomic inequity by HDI (local factors)
➡ Adherence to clinical guidelines (local protocol)
on
🔥 Clinical outcomes
Massive 🙏to promoters & collaborators!
hpbonline.org/article/S1365-…
Nik Machairas retweeted
💫 Building the next gen of HPB Surgeons ✨
Read about the new @EAHPBA programs
👩🎓 Early Career Group
🖥️ Online Academy
🧙♂️ Mentorship Program and... fellowships!
The future is (finally) already here!
👉sciencedirect.com/science/ar…
Nik Machairas retweeted
Tribute to Claudio Bassi by our chairman @SalviaRobi at the @IHPBA meeting in Cape Town. Claudio truly believed in young generations and created a training system for pancreatic surgery that is still unique natuonwide. We prouldy carry your legacy on ❤️😷 @EAHPBA @AHPBA @APHPBA
Nik Machairas retweeted
🚨PANDORINA, a binational 🇳🇱🇮🇹RCT of drain 🆚 no drain in distal pancreatectomy out in @LancetGastroHep !
✅Major morbidity 20% vs 15%
✅POPF 27% vs 12%
➡️A no-drain policy is safe and reduced POPF and should be the new standard approach
@DPCG_official thelancet.com/journals/langa…
📣 Check out our latest review article published in @jogs, focusing on state-of-the-art in simultaneous resection for colorectal cancer with synchronous liver metastases
➡️ sciencedirect.com/science/ar…
@timpawlik @MarcDiMartino @FPrimavesi @DTsilimigras @Adam_Frampton1
Nik Machairas retweeted
Out now! How many patients fail to access adjuvant therapy after surgery for resectable #PancreaticCancer?25%🥧! Why?(Data from 317 pts)
1) 🩹Postop compl
2) 🧑⚕️Oncologist's choice
3) 💊Comorbidities
Less likely:
- 👵Elderly
- 💧POPF
@PancreasVerona @EAHPBA @IHPBA @AnnSurgOncol
Nik Machairas retweeted
Laparoscopic Liver Tunnel for Tumors at the Hepatocaval Confluence @AnnSurgOncol link.springer.com/article/10…
👉 In PancreasGroup.org 2 we now seek to investigate aspects contributing to FTR on a hospital and institutional level, across various Human Development Index countries, aiming to further improve patient care and safety in pancreatic surgery 🌏🌍🌎
🚨PancreasGroup.org 2
💡Survey on Hospital Factors Affecting Failure to Rescue in Pancreatic Surgery
Participate now!
👉pancreasgroup.org/survey
✅ Complete the online Survey ⏰10min
✅ Stay anonymous
✅ No need for ethics approval
✅ PubMed citable co-authorship
Nik Machairas retweeted
🎁 It's that time of the year...
🎄 Best of Pancreas Wrapped 2023!!! 🍾
1⃣ January 2023: Pancreatic cysts when to stop surveillance !? 👇👇👇
Pancreatic cysts 🧐 When to Stop Surveillance ?!
🔥 A burning issue on @AmJGastro
🛑 STOP of follow-up depends on interval stability and size either after 5 or 10 years
Oversurveillance discouraged 🤜🤛 More evidence needed !!!
Your practice ?! 😱
journals.lww.com/ajg/Fulltex…
Nik Machairas retweeted
What is the difference between long-term survival and cure following pancreatectomy for PDAC? Check this out: Cure Probabilities After Resection Of Pancreatic Ductal... : Annals of Surgery journals.lww.com/annalsofsur… @StefanoCrippa6 @gimalleo @cuccoale @Aicep4 @AISP_Pancreas
Nik Machairas retweeted
Today in @NatRevGastroHep, review BRPC-LAPC #PancreaticCancer
📌 Preoperative chemotherapy & radiation
📌 A-B-C (re)staging & surgical decision-making
📌Clinical research agenda
Great team effort 🇩🇪🇺🇸🇳🇱 nature.com/articles/s41575-0…
Outcomes from the @PancreasGroup are now publsihed in @BJSurgery !
🚨Get ready for PancreasGroup 2, coming soon!
pancreasgroup.org/
Today a great @BJSurgery meeting and tomorrow is the World Pancreatic Cancer day 💜
😢 Pancreas surgery still associated to poor outcomes worldwide
🌍 In low human development index countries 🔺failure to rescue
🛟 Urgent measures needed!
🆓 access! academic.oup.com/bjs/advance…
Nik Machairas retweeted
Paris ‘98 Prof. Makuuchi & Belghiti started “HCC East-West Experiences”Myself, Prof. Kokudo & @VautheyMD joined. Milan ‘15: became EWALT. Mainz Nov 8-10, Prof Hauke Lang hosts EWALT 2023: join ewalt2023.de !
@IHPBA @EAHPBA @APHPBA2023 @IASGO_1988 @SSATNews @Aicep4
Nik Machairas retweeted
While >1000 worldexperts meet @ESSOnews congress #esso42 in beautiful Florence to improve care & save cancer patients life, in other parts of the world young, healthy humans and elderly people are getting killed daily. Why are we wasting the precious gift of life? #stopallwars
