@nelson_lab

Geneticist studying karrikin and strigolactone signaling in plants. Opinions are my own.

 Riverside, CA
Joined February 2015
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When a receptor becomes its own evil twin. New work from the recent Dr. Alex White Dominant-negative KAI2d paralogs putatively attenuate strigolactone responses in root parasitic plants academic.oup.com/pcp/article…

Dominant-Negative KAI2d Paralogs Putatively Attenuate Strigolactone Responses in Root Parasitic...

Abstract. Many root parasitic plants in the Orobanchaceae use host-derived strigolactones (SLs) as germination cues. This adaptation facilitates attachment

academic.oup.com
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How do karrikins and strigolactones control plant growth? A beautiful structure-function analysis by graduate student @SunhyunChang reveals a major regulatory domain that specifies the development “outputs” of SMXL proteins biorxiv.org/cgi/content/shor…
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🎉check out our latest exciting collaborative study published @ScienceMagazine with Dudareva group (Purdue U with @ShabekLab @ucdavisbiology funded by @NSF): communication in plants relies on a KAI2-mediated signaling pathway science.org/doi/10.1126/scie…

Volatile communication in plants relies on a KAI2-mediated signaling pathway

Informational exchange in plants occurs stereospecifically via volatile terpenoids and the KAI2-like signaling pathway.

science.org
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Our latest work from Dr. Qingtian Li @Qingtia95731962 We find that degradation-resistant SMXL proteins attenuate strigolactone signaling by interfering with targeting of other members of the SMXL family by D14-MAX2. sciencedirect.com/science/ar…
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Proud of the fantastic work of PhD student Changsheng Li and collaboration with great international team of scientists, here it is: Maize resistance to witchweed through changes in strigolactone biosynthesis science.org/doi/10.1126/scie…

Maize resistance to witchweed through changes in strigolactone biosynthesis

Elucidation of maize strigolactone biosynthetic pathway has the potential for controlling the parasitic witchweed Striga.

science.org
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Pretty proud of this review that @watersmt and I wrote on karrikin signaling and the (still) mysterious KAI2 ligand. 18 years after the discovery of karrikins in smoke, this field has come a long way! Final version is out now nph.onlinelibrary.wiley.com/…
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Teaching a freshmen seminar this quarter and I want to talk about bad genetics portrayals in movies and why they’re inaccurate. What are your favorites?
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✅ Genetically engineered bloodthirsty sheep (and it’s catching) ✅ New Zealand ✅ Great one-liners ✅ Sheep farts to the rescue?!
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✅ Alien DNA ✅ Evolution without all that boring waiting around for millions of years for something interesting to happen ✅ Shampoo to the rescue
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Our publication is in @NatureComms on strigolactones as chemoattractants for host tropism in Orobanchaceae parasitic plants. Thank you @ShirasuLab @nelson_lab @alex_plantnerd @riken_en @NAIST_MAIN_EN @UCRiverside ! disq.us/t/49y4r56
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Way to go, Michael!
NAASC & North American ICAR@NAASC_NA_ICAR23 Jun 2022
Michael Guzman @guzbeans from @nelson_lab gave an interesting talk on karrikins- lots of cool data and I learned something new @UCRiverside
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We are very excited to officially announce that @carogutj will join our institute @MPIMP_Potsdam as a new director to build a department focusing on mycorrhizal symbiosis. We are very much appreciating to welcome you here @PotsdamScience Park and to do exciting research together!
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Our new paper ⁦@NaturePlants⁩ is out! We combined structure function approaches & CRISPR editing in plants to elucidate the conformational switch of MAX2 #ubiquitin ligase in #strigolactone path & we found a primary metabolite that unlocks the ligase nature.com/articles/s41477-0…
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Comparative genomics in Orobanchaceae provides insight into the origin and evolution of plant parasitism biorxiv.org/cgi/content/shor… #biorxiv_plants
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Our recent work on activation mechanism of plant strigolactone receptors now featured as #CoverArt @JCIM_JCTC! Congratulations to @JFroggert for designing the cover. @ACS4Authors #MyACSCover @diwakarshukla @nelson_lab
Shukla Group@ShuklaGroup28 Feb 2022
How parasitic #plants can sense host plants via root exuded chemicals with a picomolar affinity? Our recent work with @nelson_lab looks at the activation mechanism of #strigolactone receptors in plants to answer this question. @JFroggert @diwakarshukla doi.org/10.1021/acs.jcim.1c0…
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Be our next colleague! Tenure-track Assistant Professor position at University of California Riverside in metabolomics, focusing on cellular and physiological adaptive responses in plants. aprecruit.ucr.edu/JPF01546
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Replying to @ShuklaGroup @BrianaSobecks @ChBEIllinois @Stanford @JFroggert @ugresearch_UI
Congratulations @BrianaSobecks! Check out her first author paper recently published in @JPhysChem on plant hormone receptors. pubs.acs.org/doi/10.1021/acs…

Dual Role of Strigolactone Receptor Signaling Partner in Inhibiting Substrate Hydrolysis

Abstract. Plant branch and root growth relies on metabolism of the strigolactone (SL) hormone. The interaction between the SL molecule, Oryza sativa DWARF1

pubs.acs.org
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Our addition to the growing toolkit for characterizing strigolactone receptors. We love transient expression in benthi, so why not use CRISPR to make it a better platform? Led by grad student Alex White with help from Jose Mendez and @khosla_aashima dx.doi.org/10.1002/pld3.389
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