Combatting infectious disease, working towards global health equity.
San Francisco, CA
Joined November 2014
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Matthias Pauthner retweeted
wish I was in town for this!
How can science fiction help us imagine new futures and make sense of our current civilizational struggles?
Next week: join us for a Long Now Talk with Hugo-award winning science fiction authors Becky Chambers & Annalee Newitz (@Annaleen) on Resisting Dystopia.
ALT L: A photo of the author Becky Chambers, in front of a forest backdrop. C: A photo of the author Annalee Newitz on a white background. R: The following text: Long Now Talks: Resisting Dystopia: Becky Chambers & Annalee Newitz. Tuesday April 18, 02023 7:00 PM PT
Matthias Pauthner retweeted
Today we're officially announcing and opening applications to Campus 🏛️
1/ A “school” for the soul, intellect, and inner-child:
🔭community-created curriculum exploring our curiosities
🌱 50+ circles, salons, juntos and extracurriculars
🤓 "nerd prom" at end of the qtr
Matthias Pauthner retweeted
Today @ScienceTM how a 1st-in-class #antibody cocktail targets #LassaFever virus. #CryoEM & wetlab explain how the mAbs navigate a thick #glycan shield & use 3 complementary mech. of neut. The finisher: novel vaccine candidate to elicit more Ab like these.
tinyurl.com/3vfcr23f
Matthias Pauthner retweeted
New #Ebola case in Beni, DR Congo is not a new spillover. Great work by @PlacideMbala, @labgenpath, @Inrb_goma, and others showed the new case is linked to the 2018-2020 Nord Kivu outbreak.
virological.org/t/august-202…
Matthias Pauthner retweeted
#Ebola may be back in DRC's North Kivu. Testing is underway on samples from a 46 yo woman who died at Beni on Aug. 15 of Ebola-like symptoms. afro.who.int/countries/democ…
Matthias Pauthner retweeted
I’m a partner at A16Z and we just had a very compelling healthcare pitch from a second-time founder.
Blood tests, but it only requires one drop of blood.
How cool!
I invested $351 million on the spot, making this our largest deal ever.
Will share more in a blog post soon!
Matthias Pauthner retweeted
🚨 New #LoveVirology preprint:
This paper has it all: single cells, COVID, CRISPR & Sunshine!
We systematically characterize host factors of SARS-CoV-2 using Perturb-seq.
Led by @sarasunshinebio, bringing together @JswLab, Joe DeRisi's lab & many others
doi.org/10.1101/2022.07.15.5…
1/
ALT Schematic of the Perturb-seq workflow to study SARS-CoV-2 host factors (Fig. 1A of the paper): A sgRNA library targeting host factors of SARS-CoV-2 is delivered to Calu-3 cells stably expressing the CRISPRi machinery. The cells are then infected with SARS-CoV-2 and analyzed by single-cell RNA-seq, analyzing the expression of host and viral genes in 27k individual cells, and monitoring how perturbation of host factors changes the progression of infection and the activity of antiviral pathways.
Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq biorxiv.org/cgi/content/shor… #bioRxiv
Matthias Pauthner retweeted
Sharing some more #labdaptations for #DisabilityPrideMonth. Traditional pipettes are not ergonomical & put unnecessary strain on the thumb joint. While this is a more costly investment, these pipettes allow me to keep my independence in the lab.
Matthias Pauthner retweeted
Congratulations to @CorentineLaurin on graduating. It was nice to catch up today and hear about your exciting job @WeatherwaxBio
Matthias Pauthner retweeted
I don’t know who needs to hear this, but buying books and reading books are two separate hobbies.
Matthias Pauthner retweeted
“it is easier to succeed with a hard startup than an easy one.” i have always believed this, but my confidence interval has really increased.
Matthias Pauthner retweeted
Does anyone want $228 of free @AveloAir credits?
I just had the absolute worst experience with them, and I can't imagine myself EVER using this credit again, nor would I ever send anyone I care about on this airline
Hit me up if you want it
Matthias Pauthner retweeted
Please, read the official appeal by Enamine founder and CEO Andrey Tolmachov to the Drug Discovery and scientific community.
#enamine #standwithukraine #drugdiscovery
ow.ly/PJVZ50Ib0ll
Matthias Pauthner retweeted
Cote d'Ivoire diagnoses #ebola in traveller from Guinea. Genome sequencing will tell us if the case is related to the recent outbreak in Guinea or a new outbreak. afro.who.int/news/cote-divoi…
Matthias Pauthner retweeted
Here in the Democratic Republic of Congo, a transmission chain of >90 cases was sparked when a man became sick with #Ebola for a second time. With collaborators worldwide, @K_G_Andersen's lab used #genomic surveillance to piece together the clues scripps.edu/news-and-events/… @NEJM
