Combatting infectious disease, working towards global health equity.
San Francisco, CA
Joined November 2014
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Excited to share our investigation of a very unique Ebola patient in DRC/2019 just came out. The patient relapsed from this initial infection and unfortunately sparked a large transmission chain. Fantastic work with @inrb_kinshasa and Mike Wiley‘s lab nejm.org/doi/full/10.1056/NE…
Matthias Pauthner retweeted
wish I was in town for this!
How can science fiction help us imagine new futures and make sense of our current civilizational struggles?
Next week: join us for a Long Now Talk with Hugo-award winning science fiction authors Becky Chambers & Annalee Newitz (@Annaleen) on Resisting Dystopia.
ALT L: A photo of the author Becky Chambers, in front of a forest backdrop. C: A photo of the author Annalee Newitz on a white background. R: The following text: Long Now Talks: Resisting Dystopia: Becky Chambers & Annalee Newitz. Tuesday April 18, 02023 7:00 PM PT
Please see below, VIR is looking for two SRAs in Virology – one position will be directly working with me on HIV broadly neutralizing antibody projects 🙂 If you’re interested please apply and reach out on LinkedIn/DM.
boards.greenhouse.io/virbiot…
boards.greenhouse.io/virbiot…
Matthias Pauthner retweeted
Today we're officially announcing and opening applications to Campus 🏛️
1/ A “school” for the soul, intellect, and inner-child:
🔭community-created curriculum exploring our curiosities
🌱 50+ circles, salons, juntos and extracurriculars
🤓 "nerd prom" at end of the qtr
Matthias Pauthner retweeted
Today @ScienceTM how a 1st-in-class #antibody cocktail targets #LassaFever virus. #CryoEM & wetlab explain how the mAbs navigate a thick #glycan shield & use 3 complementary mech. of neut. The finisher: novel vaccine candidate to elicit more Ab like these.
tinyurl.com/3vfcr23f
Matthias Pauthner retweeted
New #Ebola case in Beni, DR Congo is not a new spillover. Great work by @PlacideMbala, @labgenpath, @Inrb_goma, and others showed the new case is linked to the 2018-2020 Nord Kivu outbreak.
virological.org/t/august-202…
Matthias Pauthner retweeted
#Ebola may be back in DRC's North Kivu. Testing is underway on samples from a 46 yo woman who died at Beni on Aug. 15 of Ebola-like symptoms. afro.who.int/countries/democ…
Matthias Pauthner retweeted
I’m a partner at A16Z and we just had a very compelling healthcare pitch from a second-time founder.
Blood tests, but it only requires one drop of blood.
How cool!
I invested $351 million on the spot, making this our largest deal ever.
Will share more in a blog post soon!
Okay, this is the biggest bullshit I've read all day; maybe there is no hope for some SV VCs – no accountability, no ethics.
Maybe Elizabeth Holmes will need a cool $100m in prison for the next big thing in diagnostics; I'm sure @a16z is on standby.
techcrunch.com/2022/08/15/a1…
Matthias Pauthner retweeted
🚨 New #LoveVirology preprint:
This paper has it all: single cells, COVID, CRISPR & Sunshine!
We systematically characterize host factors of SARS-CoV-2 using Perturb-seq.
Led by @sarasunshinebio, bringing together @JswLab, Joe DeRisi's lab & many others
doi.org/10.1101/2022.07.15.5…
1/
ALT Schematic of the Perturb-seq workflow to study SARS-CoV-2 host factors (Fig. 1A of the paper): A sgRNA library targeting host factors of SARS-CoV-2 is delivered to Calu-3 cells stably expressing the CRISPRi machinery. The cells are then infected with SARS-CoV-2 and analyzed by single-cell RNA-seq, analyzing the expression of host and viral genes in 27k individual cells, and monitoring how perturbation of host factors changes the progression of infection and the activity of antiviral pathways.
Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq biorxiv.org/cgi/content/shor… #bioRxiv
Matthias Pauthner retweeted
Sharing some more #labdaptations for #DisabilityPrideMonth. Traditional pipettes are not ergonomical & put unnecessary strain on the thumb joint. While this is a more costly investment, these pipettes allow me to keep my independence in the lab.
Matthias Pauthner retweeted
Congratulations to @CorentineLaurin on graduating. It was nice to catch up today and hear about your exciting job @WeatherwaxBio
Matthias Pauthner retweeted
I don’t know who needs to hear this, but buying books and reading books are two separate hobbies.
Matthias Pauthner retweeted
“it is easier to succeed with a hard startup than an easy one.” i have always believed this, but my confidence interval has really increased.
Reflecting back on this weeks episodes of The Daily, showcasing the corruption/COIs of Joe Manchin and Clarence/Ginni Thomas.
Stark reminder of prevalence of political corruption in western democracies, something to keep in mind when we hold our heads high looking elsewhere.