zoological psychologist ・ fond of small data ・ statistical geneticist ・ Senior Research Fellow @EdinUniBrainSci @EdinUniMentalH・ routinely curious
Edinburgh, Scotland
Joined February 2007
- Tweets22.4K
- Following568
- Followers1K
- Likes3.2K
Mark James Adams retweeted
Humpty dumpty sat on a wall. Eating some snacks and reading a book. Oh, this was a different day. We shouldn't be defined by our worst moment.
Mark James Adams retweeted
Traveling through Twitter as through a galaxy in which thought-fragments & snatches of poetry reverberate with a startling intimacy....
Mark James Adams retweeted
....we are astonished to discover in the thoughts of others our own thoughts & in the passions & playfulness of others, our own...
Mark James Adams retweeted
Twitter makes of loneliness something rich & unexpected. But you must choose your travel-companions with care.
Mark James Adams retweeted
Out today in @ScienceMagazine, our paper on cross-trait assortative mating and why estimates of genetic correlations (i.e. shared genetic effects on phenotypes) are likely inflated. See this thread from the preprint for an overview of the idea and results
New from Richard Border @andywdahl @flint Noah Zaitlen myself & others. Estimated genetic correlations between traits may be inflated by cross-trait assortative mating (xAM): biorxiv.org/content/10.1101/…. So are apparent genetic relationships between traits a statistical artefact? 🧵
Mark James Adams retweeted
Okay everyone, before you all go tooting at Mastodon, please consider subscribing to my new substack newsletter: GWAS stories. If not via Twitter, let's keep in touch at least via occasional emails.
open.substack.com/pub/gwasst…
Mark James Adams retweeted
Why do complex traits differ in their genetic architecture?
Surprisingly, we find that two simple scaling laws explain why the number, effect sizes and frequencies of causal variants differ between traits.
Work with @GuyS2747 & @jkpritch.
biorxiv.org/content/10.1101/…
Thread 🧵
Mark James Adams retweeted
New paper @CommsMedicine "Feasibility and ethics of using data from the Scottish newborn blood spot archive for research" from @genscot - includes work I did before I left the team in 2012 - thanks for making me a co-author! @MarioniGroup #Epigenomics rdcu.be/cWZOC
Mark James Adams retweeted
🚨I'm hiring a postdoc @MountSinaiNYC to work on a collaborative project with @david_a_knowles to understand networks underlying neuropsych disorders! Ad: mountsinaigeneticscareers.or… I'll be at #WCPG2022 this week and happy to chat with anyone interested!
Mark James Adams retweeted
A third of ImageNet categories are animals, but what do they actually contain? 🐒🐦🦝🦊🐺🐗🦓🦒
@david_rolnick and I worked with ecology experts to dig deeper and wrote a paper about it! arxiv.org/abs/2208.11695
A 🧵 with our findings:
ALT Examples of images of animals from ImageNet-1k, including artificial animals (the top left image contains a man hugging a stuffed dugong plushie), collages (the top right image contains a collage of many images of birds and geese), blurry images (the center left image contains a very blurry goldfish), images with humans (the center right is a of a man holding a small fish that is dead), images with multiple species of animals (the bottom left image contains a zebra with its ear being licked by a bull) and images that are bizarre in other ways (the bottom right image is just plain creepy: a wombat in a dress with butterfly wings and human hands).
Mark James Adams retweeted
Updated best practice for estimating liability scale h2 and covg from case-control GWAS meta-analyses using methods such as ldsc. The fix is simple. Non-paywalled version here (led by @Andrew_Grotz): authors.elsevier.com/c/1faKv…
SNP-based heritability may be higher than we thought from @Andrew_Grotz @tuckerdrob @michelnivard et al
Pervasive Downward Bias in Estimates of Liability-Scale Heritability in Genome-wide Association Study Meta-analysis: A Simple Solution biologicalpsychiatryjournal.…
Mark James Adams retweeted
My matrix visualizations with MIT Gilbert Strang. I compiled the graphics in a short(14-page) PDF paper!
github.com/kenjihiranabe/The…
Mark James Adams retweeted
Paris syndrome has gone viral on Twitter. Perfect time to revisit this video work by Chinese-Austrian artist Jun Yang
vimeo.com/92478114/descripti…
Mark James Adams retweeted
“This is Andy, isn’t he adorable?” #dalle2
ALT An A.I. generated image of a dog with white fur, after Andy Warhol’s Self portrait (hair on end)
Mark James Adams retweeted
Delighted to see this preprint from @LukeAnderTroc and others finally drop! See Luke's thread for a summary of the main findings. I'd like to talk a little bit more about the simulations ... 🧵
🔥🔥🔥New Preprint: “On the Genes, Genealogies, and Geographies of Quebec”
Using a genealogy with 5M linked records, we present a high resolution model for the appearance of genetic variation in an extended settler population.
biorxiv.org/content/10.1101/…
🧵for details
1/6
Mark James Adams retweeted
New in #fleamarketresearch — I found an old photo postcard of a flood, but was even more fascinated by what I didn’t find: pictures of drought. theatlantic.com/ideas/archiv…
Mark James Adams retweeted
🎉Also out today in @NatureGenet from Brian Charlesworth, Michael E. Goddard, Karin Meyer, Peter M. Visscher, Bruce S. Weir & @WrayNaomi
🧑🏿🔬From Mendel to quantitative genetics in the genome era: the scientific legacy of W. G. Hill 🧬
⬇️
go.nature.com/3yVodPz
Mark James Adams retweeted
It gets me down to see this all the time - you either have professional experience or lived experience, you can't have both.
This is from a leading mental health organisation which will remain nameless. There's no option to choose more than one item.
Mark James Adams retweeted
All the climate data: catalogue.ceda.ac.uk/uuid/4d… – at Ipswich, England