Assistant professor at U Chicago. Studying the population genetics of complex traits. Join my lab, where the science is fun and the traits are complex!
Chicago, IL
Joined November 2016
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I'm thrilled to announce that I've joined the Section of Genetic Medicine at the University of Chicago as an assistant professor! The Simons lab is officially open!
yuvalsimons.org/
The Carlson Lab at the University of Rochester is recruiting researchers at all levels!
Please reach out to Maryn (marync.github.io/carlsonlab/…) if you are interested in groundbreaking problems in population and quantitative genetics. Maryn is brilliant and will be a great mentor!
Amazing work by @XuanyaoLiu showing how to go from gwas to biology!
Yuval Simons retweeted
Our work is featured on the cover!
New issue is out👉cell.com/cell/current
Introducing DANDELION, a method to identify core genes of complex traits, the cover depicts a lung adorned with dandelions and background patterned with ATCG sequences representing application of the framework to reveal new asthma genes
Yuval Simons retweeted
Our paper is out today in Cell, "Trans-regulatory gene mapping prioritizes disease drivers in asthma", cell.com/cell/fulltext/S0092… 🎉 GWAS hands us thousands of disease-linked variants, but the genes that actually drive the disease often aren't the ones sitting at those variants.
Yuval Simons retweeted
Temple Israel is releasing photos of the devastation in order "to take back control of our narrative," the congregation said in a statement.
I am posting these photos, which were taken by Emily Elconin, with permission.
Yuval Simons retweeted
נתקלתם באחד כזה?
להתרחק ולהזעיק את המשטרה!
מדובר בפצצונות שמתפזרות מרקטות חיזבאללה. כל תזוזה תגרום לפיצוץ ופיזור רסס קטלני. מדובר בסכנת חיים.
⚠️⚠️⚠️⚠️⚠️
Yuval Simons retweeted
Our paper, “Protein–protein interactions shape trans-regulatory impact of genetic variation on protein expression and complex traits,” is now online in Nature Genetics.
Link 👉 nature.com/articles/s41588-0…
My first paper as a PI is now out on PNAS!
pnas.org/doi/full/10.1073/pn…
Yuval Simons retweeted
Our lab at the Weizmann Institute was hit tonight by Iran
We will rebuild and return 💪
Yuval Simons retweeted
When should adaptation arise from a polygenic response versus few large effect changes? biorxiv.org/content/10.1101/… #biorxiv_evobio
What is epistasis?
New preprint X-torial!
(Work by the wonderful postdocs Maryn Carlson and Bryan Andrews)
biorxiv.org/content/10.1101/…
However, in a third system (GB1-IgG binding, Olson, Wu and Sun 2014) our method struggles because of the interplay of mutation effects on both protein binding and folding, suggesting the need to expand our work to consider two (or more) underlying scales of effect.
