Hoffmann Lab @GladstoneInst | @UCSF We focus on developing innovative vaccine technologies 🦠 🧬 🥼 Managed by Hoffmann Lab members

San Francisco, CA
Joined October 2022
Gladstone’s Magnus Hoffmann (@mhofflab) seeks to advance a new generation of more effective vaccines, improved drug delivery methods, and a greater overall understanding of vaccine-induced immune responses. bit.ly/4hDlmzm
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The promising pan-sarbecovirus vaccine from @Caltech sciencedirect.com/science/ar… @CellCellPress
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Caltech researchers, led by Professor Pamela Björkman, have imaged an elusive HIV protein structure at the atomic scale, offering unprecedented insights into the HIV infection process. #WorldAIDSDay2023 caltech.edu/about/news/imagi…
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🔬 Exciting findings in our latest publication out in @nature! This work delves into the dynamic world of HIV-1 envelope structures, revealing distinct conformational changes during host receptor (CD4) engagement. 🧬💡
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The antibodies produced by the new vaccine were effective against the original strain of SARS-CoV-2, the delta variant, and omicron variants. caltech.edu/about/news/new-v…
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A novel vaccine strategy that combines the flexibility and speed of mRNA and superior nanoparticle immunogenicity (VLPs-virus like particles) cell.com/cell/fulltext/S0092… @seth_zost @RHCarnahan cell.com/cell/fulltext/S0092… @bjorkmanlab @Caltech
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Don't miss our latest webinar happening Monday! Join @mhofflab @Caltech, @AnnaBlakney @UBC, @AliasgerSalem @uiowa, and Jinjun Shi @harvardmed as they discuss rapidly evolving vaccine technology. 📆 Monday, February 27 @ 1:30 PM EST Claim your spot now: ow.ly/M75y50N1sBF
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Dr Kim Dam is representing the Bjorkman Lab and @mhofflab at the CAVD Norman L. Letvin Early Career Investigator Conference in South Africa! We couldn’t ask for a better scientist to showcase our work to the world ☺️
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Learn more about this study and novel #vaccine technologies at our webinar. @mhofflab @Caltech, @AnnaBlakney @UBC, @AliasgerSalem @uiowa, and Jinjun Shi @harvardmed will discuss recent breakthroughs in vaccine development. 📅Feb 27 @ 1:30PM ET Register: ow.ly/9GSe50MCx7J
Check out our preprint describing the EABR technology, which enables combining features of mRNA- and protein nanoparticle-based vaccines through genetic encoding of self-assembling enveloped virus-like particles (eVLPs)! doi.org/10.1101/2022.12.26.5… Collab with @bjorkmanlab! 🧵(1/n)
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I’m hiring a postdoc and lab manager to join my new lab (bit.ly/3Yjy37P) @Stanford @Stanford_MCP! We are seeking creative team members to study and engineer protein homeostasis in human cells. Lab manager bit.ly/3JDMS1a Postdoc bit.ly/3YmhSXg Please🔃
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Please tune into this week's episode of Science Friday, where our very own Dr. Pamela Bjorkman talks about our lab's efforts to create a Pan-coronavirus vaccine sciencefriday.com/segments/n…
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Congrats to Dr. Kim Dam of the Bjorkman Lab and @mhofflab for being named a CAVD Norman L. Letvin Early Career Investigator! She will be presenting her research at the CAVD Africa Regional Meeting in Cape Town later this year. Keep up the amazing work!
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Fantastic talk by the legendary Pamela Björkman @bjorkmanlab today at the Nobel Forum symposium @karolinskainst
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The @bjorkmanlab at @caltech structurally characterized germline versions of the VRC01-class bNAb, BG24, bound to Env. They reveal mechanisms of germline binding, informing the design of VRC01-class targeting immunogens. go.nature.com/3WizpzL
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Big week in the Bjorkman lab! Magnus Hoffmann has officially started his independent research in the @mhofflab , Zhi Yang is leaving us for a new Postdoc, and most importantly, Kim Dam has successfully defended her Graduate Thesis! We are so proud of you guys!!
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Check out our latest work! We structurally characterized germline versions of the VRC01-class bNAb, BG24, bound to #HIV Env using #CryoEM. This work reveals mechanisms of germline binding, informing #vaccine design! Great work by our graduate student, Kim! nature.com/articles/s41467-0…
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Check out how #NIHHighRisk Early Independence Award recipient Magnus Hoffmann (@mhofflab) of @Caltech is creating #nanoparticles to develop vaccines against HIV, SARS-CoV-2, and other viruses: caltech.edu/about/news/five-…
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