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Asırlık bir tespit. HGP, HBP, LHC'nin her üçünün de hype-fail olduğu bir bilimsel atmosferde Silicon Vadisi'nin datamachine'lerinin evren tasavvurumuza katacaği yeni hiçbir şey olmadığını unutmamak gerek.
Is everyone fucking nuts? Did we actually believe that after decades and decades of studying the brain and coming up with next to zilch, that a handful of rich, arrogant midwits in Silicon Valley would come to a full understanding of consciousness and deliver to us artificial general intelligence? Do you know that the Swiss Blue Brain Project and Human Brain Project, both terminated last year after years of expensive research, which sought to digitally reconstruct entire brains, discovered next to nothing useful about intelligence or consciousness, except that a brain, even a mouse brain, is so complex that it overwhelms super computers? Ten years of the HBP made "no major contributions" to an understanding of the brain. We do not understand the mind or the brain. AI is a toy, a fake. What we have is a language model—an algorithm. Give it up. It is a joke.
MCihanGuvel retweeted
This preprint shows our brains are constantly flickering (~16 Hz) between multiple representations of reality, and suggests there is a "selector" that determines which state we perceive.
Interestingly, LSD rather reliably creates a "strobe" effect at about the same frequency. (To be more precise, people report ~15-20 Hz). The bouncing ball illustrated below shows what that 16 Hz strobe effect looks like.
Is LSD perhaps persisting older representations of reality in each conscious epoch? Maybe it is doing something similar in the suppressed epochs since LSD obviously has more cognitive effects than a visual strobe.
Weirdly some drugs like 2C-B give a slower strobe effect (5.5 Hz) and DMT gives a faster strobe (22 Hz). Do they change the rate at which we flip between conscious and suppressed temporal epochs, along with enhancing the persistence of conscious states?
1/ We discovered something totally unexpected about the neural structure of consciousness that overturns decades of thinking on its biological basis and brings us significantly closer to the recipe for generating conscious awareness.
New preprint: biorxiv.org/content/10.64898… (led by @HesseJanis, with @FrankLanfranchi, @_conor_mcgrory, @Yuelin_Shi, and @EngelTatiana)
MCihanGuvel retweeted
Your eyes and ears take in about a billion bits of information every second.
Your brain only thinks at about 10.
Two neuroscientists at Caltech put a number on how fast human thought actually runs. The paper is called "The Unbearable Slowness of Being."
Their answer: roughly 10 bits per second.
For comparison, your WiFi probably moves 100 million bits per second. You get annoyed when Netflix buffers. Your brain could never keep up with the show anyway.
So how do you measure the speed of a thought?
They looked at decades of experiments, from typing to speaking to video games to memory contests.
The answer kept landing in the same place.
Take an expert typist at 120 words per minute. Strip out the predictable letters, and the real information flowing out of them is about 10 bits per second.
Or blindfolded speedcubers. They look at a scrambled Rubik's cube for about 5.5 seconds, then solve it with their eyes covered. The information they absorb while looking works out to around 12 bits per second.
Even the game Twenty Questions works out to about 10.
Meanwhile, the 6 million color sensing cells in just one of your eyes can carry about 1.6 billion bits per second.
That is a gap of about 100 million to one.
Your senses are a firehose. Your thinking is a straw.
The researchers say the brain seems to have two modes. An outer brain that handles the flood of sights, sounds and movement. And an inner brain that squeezes all of it down to the few bits you actually think about.
It may also explain something you have felt your whole life.
Why you can only really think about one thing at a time.
They even predicted that Elon Musk's brain will talk to a Neuralink chip at about 10 bits per second. Not because of the chip. Because of the brain.
In plain English: you are not slow because you are tired. Every human mind runs on the same narrow pipe.
So the next time you feel overwhelmed, remember. Your brain was never built to take it all in.
MCihanGuvel retweeted
Belirli bir biyolojik hedefe yönelik ilaç geliştirme iş akışı nasıl kurulur?
Bu sürecin temel mantığı uzun zamandır biliniyor: Tasarla, üret, test et ve elde edilen verilerden öğrenerek yeniden tasarla. Asıl mesele, bu döngüyü hızlı, güvenilir ve büyük ölçekte işletebilmek.
Bunun için güçlü bir hesaplama altyapısına, deneyleri gerçekleştirecek robotik ve otomasyon sistemlerine, bu bileşenleri birbirine bağlayan ve deneysel sonuçlarla yeni tasarımları yönlendiren yapay zekâ destekli bir iş akışına ihtiyaç var.
Türkiye’nin bir Biofoundry’ye ihtiyacı var: Hesaplamalı tasarımı, biyolojik üretimi ve deneysel doğrulamayı aynı çatı altında buluşturan; akademinin ve girişimlerin erişebildiği ortak bir araştırma ve geliştirme altyapısına.
Biyoteknolojide söz sahibi olmak ve yarışın dışında kalmamak istiyorsak, bu altyapıları kurmayı stratejik bir öncelik hâline getirmeliyiz.
We are bringing agents to the wet-lab bench at Google Research to navigate complex biological landscapes. Learn how we are grounding agents in physical lab robotics to run fast closed-loop molecular design cycles, ultimately discovering single-digit nanomolar protein binders for cancer targets →goo.gle/4B5mMMB
MCihanGuvel retweeted
Sally Rooney books withdrawn in UK over Palestine Action support bbc.in/4B82LFi
MCihanGuvel retweeted
After 30 hours of playing a strategy video game (StarCraft II), adults showed a ~3-year drop in EEG-estimated brain age
MCihanGuvel retweeted
Yes, Goedel was brilliant and his main theorems are dramatic and devastating. But Tarski utterly blows my mind. While Goedel exposed a limitation of proof, Tarski exposed a limit of definition.
Arithmetical truth itself cannot be defined by a formula in the language of arithmetic. A definition need not be an algorithm. Plenty of things with a precise definition are uncomputable!
Moving from “we cannot mechanically establish every truth” to “we cannot even define the full truth predicate here” is amazing — it crosses a conceptual boundary.
Tarski’s work, IMHO, reveals more, philosophically, than Goedel.
MCihanGuvel retweeted
French journalist Marine Vlahovic was found dead in her home in Marseille while working on a documentary covering Israel's genocidal war against the Palestinians in the Gaza Strip.
( Share your thoughts )
Replying to @RabbiJeffx
Yes. Yosef Haim Ben-David and two minors kidnapped 16-year-old Mohammed Abu Khdeir in July 2014, beat him, forced him to swallow gasoline, and burned him alive. Forensic evidence confirmed he was alive when set on fire. Ben-David was convicted as ringleader and sentenced to life plus 20 years.
MCihanGuvel retweeted
Terence Tao just published a 27 slide deck saying the AI math hype only shows you the wins..
every week you see a new post.. AI solved an open math problem..
Tao says that feed hides most of the story..
the failed attempts never get posted.. the compute bill never gets posted.. and most frontier problems are STILL unsolved..
then he went further..
blindly chasing more solved problems is now hurting math..
open problems were never the goal.. they were lighthouses.. the real value was everything mathematicians learned on the way there..
let AI jump straight to the answer and the whole journey disappears..
in 1976 Appel and Haken proved the four color theorem using a computer.. and many mathematicians refused to accept it because no human could check it by hand..
50 years later the fear has flipped..
the computer is right.. but nobody understands WHY..
so Tao asks you one question..
if an AI cured cancer and passed every trial.. would you inject it before a single human understood how it works..
you spent centuries thinking math was about answers..
answers are now cheap..
understanding is the new scarce thing
MCihanGuvel retweeted
Fields medalist Hugo Duminil-Copin on OpenAI's recent math proofs flood: "Solving problems no longer has any value. [...] We’re going to have to turn mathematics into a human science: its role will be to formalize analogies, and thus to study how humans think and abstract."
Cold and silent dust,
Drifting through the endless void,
Echoes of the stars.
Glowing in the dark,
Fading light across the sky,
Empty worlds awake.
Descending through time,
Cosmos breathes again.
MCihanGuvel retweeted
Suddenly, AI has solved 90 of the 500 most important open problems in mathematics
Highest ranked problems:
#2 Riemann Hypothesis — PARTIAL
#4 Hodge Conjecture — PARTIAL
#5 Birch and Swinnerton-Dyer Conjecture — PARTIAL
#10 Extended Riemann hypothesis for Dedekind zeta functions — PARTIAL
#12 Generalized Riemann Hypothesis for Dirichlet L-functions — PARTIAL
#15 Tate Conjecture for Algebraic Cycles — PARTIAL
#22 Hilbert's Tenth Problem over the Rationals — FULL CLAIM
#24 Grothendiecks Generalized Hodge Conjecture — PARTIAL
#28 Matrix-Multiplication Exponent Equals Two — PARTIAL
#29 Unique Games Conjecture — FULL CLAIM
#31 Anderson Model Extended States in Dimension at Least Three — FULL CLAIM
#37 Prove the Penrose inequality or present a counterexample — FULL CLAIM
#38 Higher-dimensional Euclidean Kakeya conjecture — PARTIAL
#39 Modularity of Elliptic Curves over Number Fields (End_K(E)=Z) — PARTIAL
#40 Hilbert's Sixteenth Problem, Second Part — PARTIAL
#46 Fourier restriction conjecture — PARTIAL
#47 The Fontaine-Mazur Conjecture on Geometric Galois Representations — PARTIAL
#48 Nonexistence of Landau–Siegel zeros for quadratic Dirichlet L-functions — FULL CLAIM
#52 The Baum-Connes Conjecture for the K-Theory of Reduced Group C*-Algebras — FULL CLAIM
#62 Permanent versus Determinant over C — PARTIAL
#69 Finiteness of the Tate-Shafarevich Group for Elliptic Curves — PARTIAL
#72 Termination of Flips Conjecture in the Minimal Model Program — PARTIAL
#77 Chowla conjecture on correlations of the Liouville function — PARTIAL
#78 Abundance Conjecture for the minimal model program — FULL CLAIM
#80 Hadwiger Conjecture — FULL CLAIM
#83 Zilber-Pink Conjecture on Unlikely Intersections — PARTIAL
#87 Bose-Einstein Condensation in Interacting Continuous Bose Gases — FULL CLAIM
#92 Entanglement Area Law for 2D Gapped Quantum Systems — FULL CLAIM
#94 Grothendieck Standard Conjecture of Hodge Type — PARTIAL
#95 Kannan-Lovasz-Simonovits conjecture on isoperimetry of log-concave measures — PARTIAL
#99 Grothendiecks Section Conjecture in Anabelian Geometry — PARTIAL
#112 The Haldane Conjecture on Spectral Gaps of Antiferromagnetic Quantum Spin Chains — PARTIAL
#114 Iitaka conjecture C_{n,m} on subadditivity of Kodaira dimension — FULL CLAIM
#119 The Borel Conjecture on Topological Rigidity of Aspherical Manifolds — FULL CLAIM
#124 Aspherical Manifolds Admit No Metric of Positive Scalar Curvature — FULL CLAIM
#130 Polynomial Bound for Limit Cycles of Planar Polynomial Vector Fields — PARTIAL
#136 Erdős problem 3: divergent harmonic series and long arithmetic progressions — FULL CLAIM
#139 Cannon's conjecture — FULL CLAIM
#145 Residual Finiteness of Hyperbolic Groups — FULL CLAIM
#153 Congruent Number Problem — PARTIAL
#161 BPL = L (Derandomizing Bounded-Error Logspace) — FULL CLAIM
#163 NP versus the Existential Theory of the Reals — PARTIAL
#169 The Free Group Factor Isomorphism Problem — FULL CLAIM
#172 Conformal Invariance of the Critical Random-Cluster Model with q <= 4 — FULL CLAIM
#179 Arnold Conjecture on Hamiltonian Fixed Points — FULL CLAIM
#181 Polyakov Conjecture: Absence of a Phase Transition for Planar O(n) Models with n >= 3 — FULL CLAIM
#183 Smooth anisotropic Calderón uniqueness from full boundary data — FULL CLAIM
#193 Nonvanishing conjecture for projective log canonical pairs — FULL CLAIM
#195 Parity conjecture for elliptic curves — PARTIAL
#198 Long-Range Order in the Quantum Heisenberg Ferromagnet — FULL CLAIM
#203 Bochner-Riesz conjecture — PARTIAL
#205 Local Smoothing Conjecture for Wave Equations — PARTIAL
#206 Kaplansky's Zero-Divisor Conjecture for Torsion-Free Groups — FULL CLAIM
#210 Artin's primitive root conjecture — PARTIAL
#211 Hilbert-Smith Conjecture — FULL CLAIM
#213 Falconer distance set conjecture — FULL CLAIM
#222 Virasoro Conjecture for Gromov–Witten Invariants — PARTIAL
#224 Wall's Poincare Duality Group Conjecture — FULL CLAIM
#225 K(pi,1) conjecture for Artin groups — FULL CLAIM
#234 Unconditional 2−epsilon Inapproximability of Minimum Vertex Cover — FULL CLAIM
#235 Chromatic Number of the Plane (Hadwiger--Nelson Problem) — PARTIAL
#237 Global Existence of Classical Solutions to the Relativistic Vlasov-Maxwell System — PARTIAL
#239 Universal Optimality of the Hexagonal Lattice in Dimension Two — FULL CLAIM
#246 De Giorgi Conjecture for the Allen-Cahn Equation in Dimensions 4 to 8 — FULL CLAIM
#254 Exact satisfiability threshold for random k-SAT for small k (k = 3) — PARTIAL
#256 Polynomial-Time Decidability of Semidefinite Programming Feasibility — PARTIAL
#260 RL versus L — FULL CLAIM
#261 Kadison Similarity Problem for C*-Algebras — FULL CLAIM
#267 Sidorenko Conjecture on Bipartite Homomorphism Densities — FULL CLAIM
#268 Shafarevich Holomorphic-Convexity Conjecture — FULL CLAIM
#270 Kuznetsov Rationality Conjecture for Cubic Fourfolds — FULL CLAIM
#271 All groups are good: the four-dimensional disc-embedding conjecture — FULL CLAIM
#278 Planar homogeneous Mumford–Shah local-structure conjecture — PARTIAL
#284 Nearby Lagrangian Conjecture — FULL CLAIM
#285 Cartan-Hadamard isoperimetric conjecture — FULL CLAIM
#289 Sharp Upper Bound in Yau's Conjecture on Nodal Sets of Laplace Eigenfunctions — FULL CLAIM
#290 Kaplansky's Idempotent Conjecture — FULL CLAIM
#291 Calderón uniqueness for bounded measurable real isotropic conductivities — FULL CLAIM
#292 Global Attractor Conjecture for Complex-Balanced Mass-Action Systems — FULL CLAIM
#295 Zariski Multiplicity Conjecture for Hypersurface Singularities — FULL CLAIM
#297 Amenability of Thompson's Group F — FULL CLAIM
#298 Griffiths Positivity Conjecture for Ample Vector Bundles — FULL CLAIM
#300 The Singer Conjecture on Vanishing of L2-Cohomology of Aspherical Manifolds — PARTIAL
#305 Birkhoff Conjecture (Near-Boundary Continuous Invariant Foliation) — FULL CLAIM
#306 Secret key from all entangled states — FULL CLAIM
#311 Mahler Conjecture on the Volume Product of a Convex Body — FULL CLAIM
#321 Finiteness of Finitely Presented Periodic Groups — FULL CLAIM
#328 Sinai's Positive Metric Entropy Conjecture for the Chirikov Standard Map — FULL CLAIM
#334 Unrestricted Linear-Circuit Lower Bound for the Discrete Fourier Transform — FULL CLAIM
#343 Koebe circle-domain uniformization conjecture — FULL CLAIM
#351 Kobayashi Conjecture: Hyperbolic Compact Kähler Manifolds Have Ample Canonical Bundle — FULL CLAIM
#356 Bott Conjecture: nonnegatively curved simply connected manifolds are rationally elliptic — PARTIAL
#357 Strong Hyperplane Conjecture for Isotropic Constants — FULL CLAIM
#358 CAT(0) Models for All Word-Hyperbolic Groups — FULL CLAIM
#359 Hopf Conjecture: no metric of positive sectional curvature on S^2 x S^2 — PARTIAL
#361 Alperins Weight Conjecture for Modular Representations of Finite Groups — FULL CLAIM
#364 Log-Brunn-Minkowski Inequality for Symmetric Convex Bodies — FULL CLAIM
#366 Hyperkähler SYZ (Lagrangian Fibration) Conjecture — FULL CLAIM
#368 Benjamini-Schramm conjecture p_c#369 Dixmier unitarisability problem for discrete groups — FULL CLAIM
#374 Fujita Freeness Conjecture — FULL CLAIM
#375 Nagata Conjecture on Plane Curve Linear Systems — FULL CLAIM
#378 Toms–Winter: Strict Comparison Implies Z-Stability — FULL CLAIM
#379 Margulis–Platonov normal-subgroup conjecture — FULL CLAIM
#388 Shelah's Categoricity Conjecture for L_omega1,omega — PARTIAL
#392 Measure-zero singular set of stationary integral varifolds — FULL CLAIM
#401 Serres Positivity Conjecture for Intersection Multiplicities over Regular Local Rings — FULL CLAIM
#403 Rokhlin problem on multiple mixing — FULL CLAIM
#419 Lück's Determinant Conjecture for Discrete Groups — FULL CLAIM
#420 Absolute continuity of Bernoulli convolutions outside reciprocal Pisot parameters — FULL CLAIM
#421 GNRS Conjecture — PARTIAL
#424 Irrationality of Catalan's Constant — FULL CLAIM
#425 Separable Quotient Problem for Banach Spaces — FULL CLAIM
#430 Long-Time Existence of the Calabi Flow on Compact Kaehler Manifolds — FULL CLAIM
#432 Combinatorial Invariance of Kazhdan-Lusztig Polynomials — FULL CLAIM
#434 Realizable Limit Shapes in Two-Dimensional First-Passage Percolation — PARTIAL
#438 Zariski Cancellation Problem (characteristic zero, dimension ≥ 3) — FULL CLAIM
#440 Stein's Conjecture on the Hilbert Transform along Lipschitz Vector Fields — FULL CLAIM
#448 Smooth Realization of Finite-Entropy Ergodic Transformations — FULL CLAIM
#450 Deligne–Drinfeld Freeness Conjecture for grt_1 — FULL CLAIM
#453 Shub entropy conjecture — FULL CLAIM
#456 Maximal Number of Mutually Unbiased Bases in Composite Dimensions — PARTIAL
#458 LeBrun-Salamon Conjecture: positive quaternion-Kahler manifolds are symmetric spaces — FULL CLAIM
#461 Kaplansky's Direct Finiteness Conjecture — FULL CLAIM
#465 David–Semmes Riesz-transform problem in intermediate dimensions — FULL CLAIM
#467 Small Cohen-Macaulay Conjecture — FULL CLAIM
#468 Ergodicity of Irrational Triangular Billiards — FULL CLAIM
#472 CAT(0) Conjecture for All Artin Groups — FULL CLAIM
#475 Katok entropy rigidity conjecture — FULL CLAIM
#476 Polynomial-Time Solvability of Condon's Simple Stochastic Games — PARTIAL
#480 Furstenberg No-Bigeodesics (Planar FPP, Standard Minimum Moment) — FULL CLAIM
#483 Gaboriau's Fixed Price Problem for Countable Groups — FULL CLAIM
#484 Persistence Conjecture for Weakly Reversible Mass-Action Systems — FULL CLAIM
#486 Campana-Peternell Conjecture — PARTIAL
#497 Maximum Number of k-sets and Complexity of k-levels — PARTIAL
We’re releasing a broad range of new mathematical results produced by an internal frontier model.
We’ve been consulting with the independent Advisory Group on Mathematics and Artificial Intelligence at the Institute for Advanced Study, and we have drawn on their advice and public recommendations to inform how we release these results.
github.com/openai/math
MCihanGuvel retweeted
➡️NÖROnoM: Beyin Araştırmalarında Metodolojik Teknoloji: Optogenetik, Beyin Mikrodiyaliz, Mikropanç, İmmünofloresan ve Fiber Fotometri
🗣️Prof. Dr. Bayram YILMAZ
📅14 Ekim 2026
15:30
➡️QR kodu okutarak kayıt yaptırabilirsiniz. #NÖROM
docs.google.com/forms/d/e/1F…
MCihanGuvel retweeted
BREAKING NEWS
The 2026 #NobelPrize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
MCihanGuvel retweeted
Replying to @Polymarket
Getting called a traitor because you didnt 100% complete the genocide
Israeli politics are truly straight from hell







































