Understanding complex systems at @CRGenomica Tweets are from lab members 😎👨💻👩🔬👨🔬👩💻
Joined February 2021
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Congratulations to @m1quelag on his latest work!! A three-years-old project finally published!!
Cancer dysregulates thousands of exons; some are drivers and could lead to therapies. But which ones?
Similar to VEP models for mutations, we model potential cancer driver exons genome-wide and predict exon fitness in cancer.
@NatureComms: doi.org/10.1038/s41467-024-5…
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Congratulations to @YamileAna2 and @d_gerngross on their latest publication!
It was really great to work with Yamile and Luis (@lab_serrano) on this project!
Check out our article if you want to know more about how to expose or secrete proteins with Mycoplasma pneumoniae: doi.org/10.1186/s12934-024-0…
serranoLab retweeted
It was really great to work with Yamile and Luis (@lab_serrano) on this project!
Check out our article if you want to know more about how to expose or secrete proteins with Mycoplasma pneumoniae: doi.org/10.1186/s12934-024-0…
serranoLab retweeted
The @HMar_research participates in one of the projects selected in the #CaixaResearch Health Research 2024 call
Dr. @TCeliaTerrassa will participate in a project led by @lab_serrano at @CRGenomica.
@CaixaResearch @FundlaCaixa
imim.es/news/673/the-hospita…
serranoLab retweeted
🎉Congratulations to @piacosma and Luis @lab_serrano, who have each been awarded nearly one million euros by #CaixaResearch to drive groundbreaking research tackling blindness and lung metastasis.
🔗 ow.ly/WgBT50U7IPY
serranoLab retweeted
review by @lab_serrano discusses bacteria-based live biotherapeutics ➡️ embopress.org/doi/full/10.10…
serranoLab retweeted
🎙️ Miquel Anglada Girotto's talk 📣
@m1quelag
@CRGenomica
@lab_serrano
youtu.be/Fx9ScJt0o9M
#genomics #openscience
New review from the lab! We take a look at the state of the field of bacterial Live Biotherapeutic Products. Congratulations to all authors involved. 🧫🦠 @IreRodArc @YamileAna2
embopress.org/doi/full/10.10…
serranoLab retweeted
Catch @xavier_heal and I presenting our latest publications this coming thursday at the @OpenBoxSci seminar!
OBS #Genomics Seminar
📆 Thursday, 9/26, 11 am ET/5 pm CET
🎙️
Miquel Anglada Girotto (Centre for Genomic Regulation)
🎙️
Xavier Hernandez Alias
👉 Registration: us02web.zoom.us/meeting/regi…
#openscience
Moderator: @asalboix
serranoLab retweeted
Happy to see this work out after a long journey. Prioritization and modeling + experimental validation of cancer-driver exons with therapeutic potential in different cancer types. Beautifully led by @m1quelag
@CRGenomica @lab_serrano
Cancer dysregulates thousands of exons; some are drivers and could lead to therapies. But which ones?
Similar to VEP models for mutations, we model potential cancer driver exons genome-wide and predict exon fitness in cancer.
@NatureComms: doi.org/10.1038/s41467-024-5…
🧵
serranoLab retweeted
Congratulations to the five #BISTCommunity researchers for their #ERCPoC grants in the latest @ERC_Research call:
🏅Eva Novoa & Luis Serrano @CRGenomica
🏅Gerasimos Konstantatos @ICFOnians
🏅Marcos García Suero @ICIQchem
🏅Samuel Sánchez @IBECBarcelona
➡️bist.eu/five-bist-community-…
Check out the latest pre-print from the lab!
Can we measure changes in splicing factor “activity”? 🤔
In complex samples like cancer, it's tricky because SF activity is regulated by more than just expression changes or mutations.
Check out our new collab between @lab_serrano and @califano_lab: t.ly/mitjX
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serranoLab retweeted
I am so happy to receive this award!! Thank you so much @UPFBarcelona
It is a great honour to share it with great colleagues from @CRGenomica 😍
And a special thanks to my great supervisors and mentors @lab_serrano @MartinHSchaefer for the exciting journey together!
🎓 Eight doctoral students from the PhD Programme in #Biomedicine will receive the @UPFBarcelona Doctoral School PhD Extraordinary Award
Congratulations to you all! 👏🏽💐💫
Have a look at their projects following this thread 👇🏽
👉🏽tuit.cat/iz7Wy
serranoLab retweeted
Beyond thrilled to see one of @kourtisSavva's brilliant ideas published today in @ScientificData @NaturePortfolio
🔥🔥Detection of differential bait proteoforms through immunoprecipitation-mass spectrometry data analysis🔥🔥
nature.com/articles/s41597-0…
😶🌫️😶🌫️😶🌫️HAVE YOU EVER DREAMED OF IDENTIFYING MULTIPLE PROTEOFORMS OF YOUR PROTEIN OF INTEREST IN A SINGLE IP-#mass_spectrometry?💥💥💥
@KourtisSavvas from our lab found the way 🤩
👇👇
doi.org/10.1101/2024.01.23.5…
New work published today! We develop a platform for screening of biomedically relevant proteins in the fast-growing Mycoplasma feriruminatoris.
@CRGenomica @IOM_network @UPFbiomed
Find it here:
microbialcellfactories.biome…
New paper published! We report the engineering of safer strains of Mycoplasma pneumoniae that prevent Guillain Barre Syndrome to use as a chassis for therapy. Congratulations to the authors!
@cpl_synbio @CRGenomica @IOM_network
Find the full story here:
sciencedirect.com/science/ar…
Check out our #preprint on computational antibody design!
This work resulted from a wonderful collaboration between Luis Serrano Pubul (CRG), Dewilde Maarten (KU Leuven), Savvas Savvides (VIB, Ghent University) & VIB Switch Laboratory.
Read the preprint bit.ly/3QpiUk1 describing a milestone in our de novo antibody design efforts.
Our pipeline can now design high-affinity and stable antibodies in a single round!
Fantastic collaboration with @lab_serrano
@SavvidesLab & Maarten Dewilde @KU_Leuven
serranoLab retweeted
Excited to share our latest work on #smallproteins. We have designed an identification approach using #TnSeq that together other #omics and #bioinformatic approaches increases the number of genes of Mycoplasma pneumoniae from 690 to 997!
nature.com/articles/s41467-0…
serranoLab retweeted
Had a great time at this year's #JBG2023 presenting our work characterizing the cancer splicing programs! Our first @lab_serrano @califano_lab collaboration! Thanks for the feedback and inspiring discussions! @CRGenomica @Columbia @CosmoCaixa_CAT @SCB_iec @BiBcn
ALT Person presenting slides at a conference
ALT Darwin, Curie and Einstein wax sculptures
ALT Poster session
ALT Person holding a diploma in conference hall