@lab_arnold

Mucosal immunology lab @UZH 🔬! Eosinophil fanatics👩🏻‍🔬👨🏽‍🔬, exploring their fascinating role at steady state, during inflammation 🦠 and cancer.

 Experimental Immunology, UZH
immunology.uzh.ch/en/researchunit/mucosalimmunology.html
Joined October 2021
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  • Following128
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Happy to present our data on the transcriptional regulation of eosinophils in cancer at the 2025 Granulocyte Meeting, Shanghai #ThePoweOfMany #Gmeeting2025 @lai9uan
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Wonderful time and great science in Shanghai at the #Gmeeting2025 with an exceptional line-up of speakers!
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Happy to present our new data regarding the transcriptional regulation of eosinophils in the tumor microenvironment #iuis2025 @EosinophilSoc
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Arnold_lab retweeted
Chen Varol@ChenVarol30 Jul 2025
Exciting new study from @ArielMunitz and his lab reveals a pathological role for the alarmin TSLP in eosinophilic esophagitis, highlighting it as a potential therapeutic target. It was a pleasure to collaborate on this work! onlinelibrary.wiley.com/doi/…

Distinct Roles for Thymic Stromal Lymphopoietin (TSLP) and IL‐33 in Experimental Eosinophilic...

This study described the expression and function of TSLP and IL-33 in an experimental model of EoE. TSLP and IL-33 were overexpressed in human and experimental EoE. Human and mouse esophageal MCs...

onlinelibrary.wiley.com
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We had such a great time in #Montpellier at the #IES2025. Big congratulations to our awards receivers: Glenn for the best oral abstract talk and travel grant, @danielcrepaz for best abstract slam and James for travel grant! #eosinophils
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Replying to @arnoldlab
@arnoldlab Isabelle with a great overview of eosinophil T cell interactions in a “state of the art” review 💪🏻 #IES2025 @EosinophilSoc
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wonderful time here in Montpellier: exciting science, great people and lots of eosinophils! #IES2025
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#KSMyeloid25 I am delighted to present our @lab_arnold work at the Keystone Symposia in Hannover. Visit me at the poster session and my #talk in the Granulocytes session today to hear more about neonatal #eosinophil tissue integrity functions and their impact on the microbiota! – at Herrenhausen, Hannover
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Mark your calendars for 22 January 2025! IES & EMBRN are coming together for a joint webinar on Single Cell Dissection of Human Mast Cells, Basophils and Eosinophils. Register now: eosinophil-society.org/webin… @KhouryMD @DrMMukherjee @RossanaMelo5
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Read our exciting new story about the #eosinophil - #macrophage axis that controls tumor metastasis in CRC 📕
Arnold_lab@lab_arnold18 Dec 2024
We are very excited to announce the release of our latest preprint exploring eosinophil dynamics in colorectal cancer (CRC)! 🧬🧫👩‍🔬 biorxiv.org/content/10.1101/… Find our key findings in the comments below! #colorectalcancer #eosinophils #spp1macrophages #tumormicroenvironment

Eosinophils restrict CRC metastasis by inhibiting pro-tumorigenic SPP1+ macrophage differentiation

Eosinophils, traditionally associated with allergic responses, have emerged as critical immune modulators in colorectal cancer (CRC). Here, we reveal that eosinophils actively shape the tumor...

biorxiv.org
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We are very excited to announce the release of our latest preprint exploring eosinophil dynamics in colorectal cancer (CRC)! 🧬🧫👩‍🔬 biorxiv.org/content/10.1101/… Find our key findings in the comments below! #colorectalcancer #eosinophils #spp1macrophages #tumormicroenvironment

Eosinophils restrict CRC metastasis by inhibiting pro-tumorigenic SPP1+ macrophage differentiation

Eosinophils, traditionally associated with allergic responses, have emerged as critical immune modulators in colorectal cancer (CRC). Here, we reveal that eosinophils actively shape the tumor...

biorxiv.org
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📌 Eosinophils suppress peritoneal metastases by modulating the differentiation of pro-tumorigenic SPP1+ TAMs
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📌 This novel eosinophil-macrophage axis may open new avenues for controlling CRC progression and metastasis.
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Our key findings include: 📌 Eosinophil activation patterns and transcriptional programs are conserved within tumors in mouse and human CRC
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Abstract submission is now open for the 13th Biennial Congress—taking place 7–11 July 2025 in Montpellier, France! Submit here: eosinophil-society.org/congr… Key Deadlines: Abstract Submission: 16 March 2025 Late-Breaking Abstracts: 15 May 2025 Presenter Registration: 1 June 2025
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Join Our Research Team! We study immunological mechanisms of allergic diseases, and how these mechanisms may participate in cancer. See: munitzlab.com Or: pubmed.ncbi.nlm.nih.gov/?ter… MSc, PhD & postdoc positions available. DM or mail me with your CV and cover letter 😊
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MoorLab@moorlab24 Jul 2024
Check out our lab's latest paper out in @Nature! Congrats to @cocoborrelli and everybody involved 🎉🥳
Andreas E. Moor@AndreasMoor24 Jul 2024
How are cell-cell interactions governing successful metastatic colonization in the liver? Have a look at our new paper in @nature that introduces an in vivo proximity screen to functionally test cellular interactions in a high-throughput manner. nature.com/articles/s41586-0… 🧵

In vivo interaction screening reveals liver-derived constraints to metastasis

Nature - Interactions between plexin B2 on hepatocytes and sempahorins on disseminated tumour cells regulate metastatic seeding in the liver.

nature.com
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How are cell-cell interactions governing successful metastatic colonization in the liver? Have a look at our new paper in @nature that introduces an in vivo proximity screen to functionally test cellular interactions in a high-throughput manner. nature.com/articles/s41586-0… 🧵

In vivo interaction screening reveals liver-derived constraints to metastasis

Nature - Interactions between plexin B2 on hepatocytes and sempahorins on disseminated tumour cells regulate metastatic seeding in the liver.

nature.com
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Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease dlvr.it/T9N3Sn
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