Innate immunologist specializing in diseases of the gut, liver and metabolic syndrome
Sourasky Medical Center
Joined September 2020
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Obesity is a disorder of disrupted energy homeostasis. We uncovered a key pathogenic role for S100A8/S100A9 in impairing energy expenditure and exacerbating obesity. Thank you @FishmanSigal for this exciting collaboration!
journals.physiology.org/doi/…
Exciting new study from @ArielMunitz and his lab reveals a pathological role for the alarmin TSLP in eosinophilic esophagitis, highlighting it as a potential therapeutic target. It was a pleasure to collaborate on this work!
onlinelibrary.wiley.com/doi/…
Chen Varol retweeted
(1/8) Just published in @AllergyEaaci
Led by @dsilvaanish66 in collaboration with @RothenbergLab @ChenVarol @AstraZeneca. We reveal a non-redundant and key role for TSLP in eosinophilic esophagitis (EoE), a chronic allergic disease of the esophagus.
onlinelibrary.wiley.com/doi/…
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The devastating Iranian attack on the WIS is not only a strike against a scientific institution—it is an assault on humanity’s future, on medicine, and on the pursuit of discovery. It undermines the very foundations of scientific research. youtu.be/7W4iqRPnScs
Chen Varol retweeted
I just watched the roughly 45-minute footage of October 7th at a private screening in NYC. Here are my immediate thoughts minutes after watching it. 🧵
Great opening today for the FEBS 2023 ECM and protease cross talk conference at the Weizmann Institute of Science. Thank you @LabSagi and Antoine Dufour for the organization and the invitation to present our work on macrophage governed ECM remodelling in cancer and liver fibrosis
Great talk by Dr. Shani Ben Shlomo from our group in the 5th International Conference on ImmunoMetabolism: Molecular and Cellular Immunology of Metabolism in Cretes, Greece.
Chen Varol retweeted
🚨To all macrophage & dendritic cell fans. Last time we organised a VIB Myeloid cell meeting we were completely sold-out within weeks. So just a warning to register in time for the #EMDS23 conference! vibconferences.be/events/emd…. Speaker list is fantastic 🤩🤩🤩. Please retweet 🙏🏼
Congratulations dear @DanielJDrucker for winning the distinguished Wolf prize, well deserved!
wolffund.org.il/2023/02/07/d…
Chen Varol retweeted
Watch @ArielMunitz from @Tel_Aviv_Uni present our original article published in @AllergyEaaci describing the development of an experimental #EoE model and demonstrating the critical role of the type II IL-4 receptor in the pathogenesis of EoE 🐁
youtu.be/SB17Th5Pijc – at Israel
Chen Varol retweeted
1/2 onlinelibrary.wiley.com/doi/…
Happy to share our recent study demonstrating the CRITICAL role of IL-13 receptor alpha 1 in eosinophilic esophagitis (EoE).
@RothenbergLab @usisraelbsf @ChenVarol @AllergyEaaci (and twitter-less Shmulik Avlas)
Chen Varol retweeted
We finish the day with @ChenVarol on the role of Commd10 in liver macrophage subsets #KSMyeloid22. Important effect om KC survival and function during liver injury model
Chen Varol retweeted
📢 Together with @KC_DC_01 we made a super cool portal for anyone to navigate the data @CellCellPress: livercellatlas.org/ This means you can take any UMAP from any figure and then check the expression of any gene or protein of interest yourself 1/2 cell.com/cell/fulltext/S0092…
Happy to share our recent study showing that COMMD10 is essential for liver Kupffer cell homeostatic survival and also for regulation of Ly6Chi monocyte differentiation and inflammatory behaviour at the diseased liver. cell.com/cell-reports/fullte…
Dear @DanielJDrucker, congratulations for the Gairdner prize. Your discoveries are translated into revolutionary therapeutic agents for the treatment of metabolic syndrome diseases and beyond. It is fun, educating, and inspiring to collaborate with you
