
#FirstGen #immigrant 🇵🇭🇺🇸. Postdoctoral fellow with @Mizuno_lab at @NIH / PhD @berkeleyMCB (@TheHurleyLab and @BustamanteLab)// Cell cartographer
United States
Joined April 2009
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King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Our paper is now published @CurrentBiology!
With our unique method to live image fertilized mouse eggs, we highlighted the importance of Ca2+ oscillations in maintaining the spindle position to ensure asymmetric cell division. Thanks to all the authors!
sciencedirect.com/science/ar…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Our work is finally out in @NatureSMB.
This study marks the last paper in my PhD, and I had the pleasure of co-leading this work with @nicklue8.
Enjoy the video summarizing our findings!
nature.com/articles/s41594-0…
Our work, co-led by @AlfredoFlorez and @NicholasLue, is finally out in @NatureSMB. Shout out to coauthors P.Grob, B. Kaeser, J.Fang, and Susanne Kassube for their contributions, and thanks to the reviewers for their suggestions that led to the final work.
nature.com/articles/s41594-0…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Our Basal Body Story is Now Online!
It’s been a long journey. Initially, we plan to understand how the basal body assembles, but along the way, we stumbled upon an unexpected opportunity to explore biogenesis as well.nature.com/articles/s41467-0…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Exciting findings from @JunLiuLab #postdoc @YueJianUSTC @YaleMed Architecture and activation of the Legionella Dot/Icm type IVB secretion machine #cryoEM #cryoET #Legionella biorxiv.org/content/10.1101/…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
External strain on the plasma membrane is relayed to the endoplasmic reticulum by membrane contact sites and alters cellular energetics | Science Advances science.org/doi/10.1126/scia…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
The MOSAIC reconfigurable microscope by @Eric_Betzig et al is finally out!
MOSAIC integrates multiple advanced imaging techniques including light-sheet, label-free, super-resolution, and multi-photon, all equipped with adaptive optics:
biorxiv.org/content/10.1101/…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Despite the chaos and turmoil, our lab is blessed to have 3 new postdoctoral fellow openings and we would welcome scientists interested in:
- combining single-molecule studies with cryo-EM
- developing new protein design tools using bioinformatics and structure-based tools
- using protein design to develop novel genome-editing tools.
Please feel free to reach out to me: [email protected] with your CV and a few sentences on what you'd like to work on in the lab.
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis
nature.com/articles/s41556-0…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
🔥 We caught SARS-CoV-2 in the act of membrane fusion—frame by frame! Using cryoET, we reveal the entire fusion sequence in near-native conditions—and how S2-targeting antibodies slam the brakes on it.
Don’t miss it 👉 nature.com/articles/s41467-0… @OxfordStrubi @eBIC_Diamond
Our study is out in Nature Communications! 🎉
We reveal the full sequence of SARS-CoV-2 spike-mediated membrane fusion & show how S2-targeting antibodies block it using cryoET in a near-native system.
🔬🦠 nature.com/articles/s41467-0…
#SARSCoV2 #CryoET #Virology #CryoEM #Antibodies
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Mitochondrial complexity is regulated at ER-mitochondria contact sites via PDZD8-FKBP8 tethering
nature.com/articles/s41467-0…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Just find the recording of this symposium is on YouTube
Cryo-EM: The Next 50 Years Symposium
youtube.com/watch?v=Y6sB8aSS…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Super interesting paper looking at the role of NFL. Clearly not only a biomarker of neurodegeneracion.
cell.com/cell-reports/fullte…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Another wonderful collaboration with
@alanbrownhms lab. The Zhang lab together with @PolinaLishko lab (co-first author
@QingweiN) contribute the doublet microtubule structure from Crithidia fasciculata, a model organism that infects mosquitoes.
science.org/doi/10.1126/scie…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Vimentin filament transport and organization revealed by single-particle tracking and 3D FIB-SEM rupress.org/jcb/article-abst…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Super excited to share our latest work just published! 🎉 Grateful for the support of my PI @TakashiAkeraLab and amazing collaborator@Melania Bruno @todd_macfarlan ! #Meiosis #ChromosomeBiology #CentromereEvolution nature.com/articles/s41467-0…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Structure of the Thin Filament in Human iPSC-derived Cardiomyocytes and its Response to Heart Disease
biorxiv.org/content/10.1101/…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Stunning paper
Parkinson’s starts in kidney
nature.com/articles/s41593-0…
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
‼️We are hiring! If you know anyone, please share/retweet. Thank you so much!‼️
King Cada ᜃᜒᜅ᜔ ᜃᜇ retweeted
Iyer, Akhmanova et al reveal that two centriolar proteins, CP110 & CPAP, show antagonistic activities at #microtubule + ends. Together, they impart very slow but processive microtubule polymerization & their interaction promotes robust #centriole formation hubs.la/Q033LnK30




















