This is a big one. 🔥 We’ve spent the last few years watching AI make huge leaps in language, images and video. Now we’re seeing the same kind of step-function progress in biology. Proteins don’t sit still. They move constantly and that’s one reason many of the most important disease targets have remained “undruggable.” @ToposBio just introduced Topos-2 + Topos-Bind to model that motion. And the benchmarks are 🤯: Topos-2 ranked #1 across 10+ models and came nearly 4x closer to experimental ground truth than the next-best model. Think of it simply: AlphaFold helped us see the picture. Topos is trying to model the movie including what happens when you introduce a drug. If this works at scale, it opens up an entirely new class of targets for drug discovery. Proud for @Boldstartvc to have partnered with @r_zarcone, @khosra and the team from inception. 🔥