@imarmean

#diagnostics #bioinformatics scientist: DNA #variation and their impact, PhD #proteomics, PostDoc #dna-variation. #STEMAmbassadors. Views are my own. 🧬 🇪🇺

 Cambridge, England
Joined January 2016
  • Tweets1.3K
  • Following294
  • Followers367
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Irina Armean, PhD retweeted
Mark Daly@dalygene1 Sep 2023
Great opportunity for early stage researchers ready for independence!
Samuli Ripatti@samrip30 Aug 2023
If you are a senior postdoc ready to start your own research group, this is a fantastic opportunity. At FIMM we host some of the globally most exciting genetic and molecular data and for a strange reason Finland ends up at the top of the happiest nation list year after year.
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Useful cheat-sheet for general genomics quantitative properties:
Jonathan Pritchard@jkpritch31 Mar 2023
Sharing this in case it's useful: I find that students often have a hard time conceptualizing quantitative parameters in genomics and popgen Here's a cheat-sheet I put together for teaching. It's also part of a textbook I have been writing on human genetics (more on that below)
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Irina Armean, PhD retweeted
PGS Catalog@PGSCatalog16 Sep 2022
📣NEW TOOL! Wish there was a tool that made calculating existing #PolygenicScores and #PolygenicRiskScores in new datasets easier? We @PGSCatalog have made just that! INTRODUCING pgsc_calc: an open-source pipeline to calculate PGS using nextflow github.com/PGScatalog/pgsc_c…
Summary of the pgsc_calc pipeline: input genotype data, reference datasets, PGS Catalog IDs and custom scoring files. The pipeline does the harmonisation and variant matching to calculate PGS!

ALT Summary of the pgsc_calc pipeline: input genotype data, reference datasets, PGS Catalog IDs and custom scoring files. The pipeline does the harmonisation and variant matching to calculate PGS!

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Irina Armean, PhD retweeted
Ryan Collins@RyanLCollins131 Aug 2022
🎉Final version of our dosage sensitivity study out today @CellCellPress! cell.com/cell/fulltext/S0092… Explored CNV associations across 54 phenotypes in ~1M genomes Since @medrxivpreprint in 2021: added 200k samples & 22 phenotypes thanks to @GeneDx @ESTbiobank @vumcdbmi 🧵👇 1/6
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Irina Armean, PhD retweeted
Konrad Karczewski@konradjk15 Aug 2022
Our paper on rare variant associations in the UK Biobank is out in Cell Genomics today! cell.com/cell-genomics/fullt…

Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,84...

Karczewski et al. generated a massive-scale association dataset between rare genetic mutations and thousands of diseases and traits and released these data in the Genebass browser. They quantify the...

cell.com
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Irina Armean, PhD retweeted
Kaitlin Samocha@ksamocha12 Jun 2022
Lovely weather in Vienna for some science! #ESHG2022 Two notes: -I’m hiring! Please say hello if you’d like to chat about opportunities :) -I’ll talk about some hot-off-the-cloud analyses of regional missense constraint on Monday (S22 session)
Kaitlin Samocha@ksamocha11 Jun 2022
On my way to #ESHG2022 in Vienna! Looking forward to meetings colleagues and chatting science.
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Irina Armean, PhD retweeted
Jordan Smoller@jorsmo5 May 2022
PRS-CSx has arrived. Congrats to @getian107 @Yunfeng_Ruan @hailianghuang and colleagues Improving polygenic prediction in ancestrally diverse populations nature.com/articles/s41588-0…
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Great postdoc opportunity with @ksamocha ! Do RT! Do apply!
Kaitlin Samocha@ksamocha22 Apr 2022
I'm hiring postdocs to join my team at @CGM_MGH & Broad! We study patterns of rare variation in large genomic datasets (like gnomAD), and leverage those into insights about genetic risk for disease. If you are interested, please reach out or apply here: partners.taleo.net/careersec…
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Irina Armean, PhD retweeted
Matt Hurles@mehurles6 Apr 2022
👇👇👇 most important advice to genomics trainees. To understand your data, and its error modes, find a simple informative plot of a slice of your data (read alignment etc) and plot for 100+ random instances. Use your brain’s pattern recognition. Takes minutes, saves months.
Mick W@tson ↙️@BioMickWatson6 Apr 2022
Replying to @nilshomer
Visualise *everything* Look at sequence reads, sequence assemblies, data, alignments, SNPs, PCA all of your numerical data. Get into the *details* of your data
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Irina Armean, PhD retweeted
EMBL-EBI@emblebi6 Apr 2022
There are different versions of the human genome annotation but which do you use? The Matched Annotation from @NCBI and EMBL-EBI (MANE) collaboration is the answer and brings new meaning to the phrase: two heads are better than one. ebi.ac.uk/about/news/researc…

The MANE collaboration: working together to support genome science

Researchers from the MANE collaboration bring you the most comprehensive human genome annotation dataset to date.

ebi.ac.uk
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Irina Armean, PhD retweeted
Kaitlin Samocha@ksamocha29 Mar 2022
Cecilia (@ceclindgren) is fabulous and a true leader in the field of genomics. Great chance to join her team. Details below 👇
Duncan Palmer@astheeggeggs29 Mar 2022
Come and work with us! The Lindgren @ceclindgren Lab at the Big Data Institute @bdi_oxford in Oxford is looking to hire a junior statistical geneticist/bioinformatician (finished or about to finish undergrad/masters): bit.ly/lindgren_bdi. Please share!
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Irina Armean, PhD retweeted
Duncan Palmer@astheeggeggs29 Mar 2022
Come and work with us! The Lindgren @ceclindgren Lab at the Big Data Institute @bdi_oxford in Oxford is looking to hire a junior statistical geneticist/bioinformatician (finished or about to finish undergrad/masters): bit.ly/lindgren_bdi. Please share!
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Irina Armean, PhD retweeted
Eric Vallabh Minikel
@cureffi23 Mar 2022
Our lab is hiring! vallabhminikel.org/jobs/ Come join our mission to cure prion disease through groundbreaking science. The folks who work here love our lab — you will too!
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Irina Armean, PhD retweeted
Nicky Whiffin@nickywhiffin7 Mar 2022
🚨 Last few days to apply for these posts - deadline is Thursday. It am truly excited by this project and working with this awesome team (kick-ass female mentors anyone?)! If you know anyone who might be interested, please please share! Thank you!
Nicky Whiffin@nickywhiffin14 Feb 2022
📢 Looking for postdocs to lead an exciting new industry collaboration with @joannahowson @novonordisk and an awesome team including @ceclindgren and @carolinefwright 🌟 Early-career postdoc: my.corehr.com/pls/uoxrecruit… Senior role: my.corehr.com/pls/uoxrecruit… Please share and RT! 1/4
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Irina Armean, PhD retweeted
EMBL@embl15 Feb 2022
Join EMBL to complete your PhD at one of our six sites across Europe! The EMBL International PhD Programme is open for applications until 19 April 2022. #PhD #research Important information about the application process can be found here: embl.org/about/info/embl-int…
Illustration featuring scientists, students, lab notebooks and information on the EMBL International PhD Programme 2022 Summer recruitment.

ALT Illustration featuring scientists, students, lab notebooks and information on the EMBL International PhD Programme 2022 Summer recruitment.

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This is happening tomorrow, Monday! Do sign up to attend: cpm.well.ox.ac.uk/ @mkveerpn @nickywhiffin @broadinstitute @covid19_hgi
Centre for Personalised Medicine, Oxford (+ bsky)@CPMOxford18 Jan 2022
We are delighted that @mkveerpn will be joining us on 7th February to give his talk, 'The Global COVID-19 Host Genetics Initiative: Mapping of the Host Genetic Architecture of COVID-19 while Improving Diversity in Genetics'. Register here to attend: cpm.well.ox.ac.uk/event/kuma…
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Irina Armean, PhD retweeted
Nicky Whiffin@nickywhiffin26 Jan 2022
Two amazing @CPMOxford talks over the next 2 weeks: - 3rd Feb the incredible @HeidiRehm🤩 on a global ecosystem for genomic medicine - 7th Feb the awesome @mkveerpn💪 on @covid19_hgi, diversity, collaboration and outreach Sign up for both: cpm.well.ox.ac.uk/content/ev… Please share!
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Irina Armean, PhD retweeted
Kathryn Lilley@lilley_ks25 Jan 2022
We can now obtain subcellular maps for both RNA and protein in the same experiment and show the dynamic changes in location of both in the unfolded protein response. Introducing LoRNA (the LOPIT for RNA) biorxiv.org/cgi/content/shor…
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Irina Armean, PhD retweeted
Ensembl@ensembl20 Jan 2022
1/ Knowing the frequency for alleles of genomic variants in populations around the world helps us understand phenotypes and disease 🌎🌍🌏 We’re here to take you through the data in @ensembl step-by-step. A thread…🧵 #genomics #bioinformatics #tweetorial #Ensembltraining🧬
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Irina Armean, PhD retweeted
Pradeep Natarajan
@pnatarajanmd6 Jan 2022
🚨Please RT: I'm hiring a computational biologist! Come join our translational team investigating the biology of cardiovascular diseases through genomics & data science within a supportive, dynamic scientific environment. partners.taleo.net/careersec… @mghcvrc @CGM_MGH @broadinstitute
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