Professor of Medicine Université de Montréal, Imperial College London, Nanyang Technological University Singapore. Wellcome Investigator.
Joined November 2014
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Guy Rutter1 retweeted
📢
#CIHR, #NSERC and #SSHRC are proud to launch the new Canada Impact+ Research Training Awards to support the recruitment of international doctoral students and postdoctoral researchers to Canada.
Learn more about this new initiative:
▶️ tinyurl.com/yc54p4da
ALT IMAGE: Background in shades of pink to orange with undulating horizontal white lines in the center. Canada logo in white at the bottom right.
Guy Rutter1 retweeted
📢Today, the #GC launched new programs to attract international researchers to Canada.
✅ Canada Impact+ Research Chairs
✅ Canada Impact+ Emerging Leaders
Get all the details here: canada.ca/en/impact-plus-cha…
@SSHRC_CRSH @NSERC_CRSNG
@CIHR_IRSC @InnovationCA @ISED_CA
ALT Launch of the Canada Global Impact+ Research Talent Initiative
Guy Rutter1 retweeted
Canada’s new government is investing big to attract world-class talent in science and technology — and become an innovation powerhouse.
ALT Screenshot from an article of the Financial Post. The headline reads: Canada launches billion dollar plan to recruit top researchers.
Guy Rutter1 retweeted
29%—That's a lot of weight loss, folks
Triple GLP-1 drug receptor retatrutide
Compares with avg weight loss with Zepbound 21%, Wegovy (Ozempic) 15%
nytimes.com/2025/12/11/healt…
Guy Rutter1 retweeted
Impaired cAMP–PKA–CREB1 signalling drives mitochondrial dysfunction in skeletal muscle during cancer cachexia | Nature Metabolism nature.com/articles/s42255-0…
Guy Rutter1 retweeted
#Throwback
REVIEW | @guy_rutter , @BennyScience et al
Exploring pancreatic beta-cell subgroups and their connectivity
nature.com/articles/s42255-0…
Guy Rutter1 retweeted
Not one, but TWO endocrinologists to join the Canadian Medical Hall of Fame in 2026. Both Drs Hegele and Zinman have changed the way we treat metabolic disorders forever. In addition though … they are just kind humans. Congratulations!!🎉🎊🎈
Join us in congratulating the #2026CMHFInductees!cdnmedhall.ca/induction
PAVEL HAMET, MD PhD
ROBERT ALEXANDER HEGELE, MD
MICHAEL D. HILL, MD
MARY R. L'ABBÉ, PhD
MORAG PARK, PhD
BERNARD ZINMAN, MDCM
@kellygrant1 @Megan_Ogilvie @LaurenPelley @DubinskiKa4985 @JenLeeCBC @Avis_Favaro
Guy Rutter1 retweeted
I‑BET151 modulates glucokinase gene expression and beta cellfunction in part through changes in FOXO1 expression rdcu.be/eIBCo
Assoc. Prof Yusuf Ali's team @NTU_LKCMedicine in collaboration with @guy_rutter and @astar_research discovered that BET protein inhibition (I-BET151) impacts pancreatic β-cell function.
🔹 ↑ Glucose excursions
🔹 ↓ Insulin response
🔹 Downregulation of MODY genes (Hnf4α, Gck, Hnf1α, Glut2) & PI3K–Akt pathway
⚠️ BET therapies may impair β-cell health — caution warranted.
#Diabetes #Epigenetics #BETinhibition
Guy Rutter1 retweeted
#Throwback
REVIEW | @guy_rutter , @BennyScience et al
Exploring #pancreatic #BetaCell subgroups and their connectivity
nature.com/articles/s42255-0…
Guy Rutter1 retweeted
Semaglutide in Adults with Type 1 #diabetes and #Obesity NEJM Evidence evidence.nejm.org/doi/abs/10…
Guy Rutter1 retweeted
A huge step forward for cell replacement therapy for #T1D @NEJM
Vertex clinical trials for zimislecel
nejm.org/doi/full/10.1056/NE…
Guy Rutter1 retweeted
"If you're working non-stop all the time you will burn out."
How do you keep a healthy work-life balance as a scientist? Hear 2009 chemistry laureate Venki Ramakrishnan share his best advice on how to achieve a good work-life balance.
#NobelPrize
Guy Rutter1 retweeted
Standing shoulder-to-shoulder with my #WashU colleagues #StandUpForScience fighting for our work and our future #standupforscience2025
Guy Rutter1 retweeted
Collaborators including @LioraKatz1, @DKSNYCMSSM, and @COttmann1433 developed highly potent, selective, active stabilizers of the ChREBPα/14-3-3 PPI with a phosphonate chemotype that display activity in both INS-1 cell lines and primary human islets.
🔗 go.nature.com/4i3zoKp
Guy Rutter1 retweeted
Hello everyone! I am helping to organize a one-day symposium on fluorescent metabolite biosensors and their use in metabolism research. It will be May 12-13 and associated with the Cold Spring Harbor Laboratory “Mechanisms of Metabolic Signaling” Symposium. Our field needs to be able to visualize metabolism with spatial and temporal resolution and this symposium will explore what to do and how to do it, with experts in metabolism and biosensor development and use. Please join us! meetings.cshl.edu/meetings.a… -JR
Guy Rutter1 retweeted
If you want to lose weight make sure you sleep enough
Sleep makes raptin which suppresses apetite
nature.com/articles/s41422-0…
Guy Rutter1 retweeted
I'm quoted in this article on how NIH is still blocked from funding new grants.
This sabotage makes no sense. Nearly every medicine or treatment you've ever received has roots in NIH-funded research, and every $1 of NIH spending generates $2.46 in returns.
wbur.org/news/2025/02/24/can…
Guy Rutter1 retweeted
Black are the constituencies won by the CDU/CSU, blue the constituencies won by the AfD. Quite staggering. Can you spot the exact location of the old inner-German border?! 🥴
Guy Rutter1 retweeted
🔬Are #betacells the only key players in #insulinsecretion?
In this episode, Mark Huising & @guy_rutter explore how alpha & delta cells shape glucose regulation. Could this lead to new #diabetes treatments?
🎧 Listen now: easd.org/media-centre/podcas…
#IsletBiology #Research
ALT Two men seated on a black couch in a modern indoor setting, engaged in a discussion while holding blue microphones. The background features large windows with a view of greenery. The image includes the EASD logo in the top right corner and a blue design overlay with a waveform graphic. The text reads: 'Islet networks regulating insulin secretion.'
