How muscle cells are built: organelle positioning, cytoskeleton and disease. Lab @ GIMM / FMUL, Lisbon.
Lisbon
Joined August 2007
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Excited to share our new Comment out in Science! 🇪🇺🔬
Europe has incredible scientific strength. We outline overlooked opportunities to empower researchers as innovators and supercharge Horizon Europe.
science.org/doi/10.1126/scie…
Happy to collaborate with @CGAlmeidaG on this paper where we studied bin1 in a context of alzheimer disease
🧠 What if Alzheimer’s risk starts at the synapse?
In our new study led by Mariana Barata, we show that BIN1, a key AD risk gene, regulates inhibitory synapses—loss of BIN1 → hyperexcitability before Aβ.
📖 cell.com/cell-reports/fullte…
#NeuroTwitter #Alzheimers #Neuroscience
Edgar R. Gomes @gomeslabo.bsky.social retweeted
🧠 What if Alzheimer’s risk starts at the synapse?
In our new study led by Mariana Barata, we show that BIN1, a key AD risk gene, regulates inhibitory synapses—loss of BIN1 → hyperexcitability before Aβ.
📖 cell.com/cell-reports/fullte…
#NeuroTwitter #Alzheimers #Neuroscience
Edgar R. Gomes @gomeslabo.bsky.social retweeted
🌍🔬 O poder invisível contra a crise climática- a célula.
publico.pt/2025/04/17/cienci…
#EMBOCells4PlanetHealth #EMBOCells4ClimateResilience
Edgar R. Gomes @gomeslabo.bsky.social retweeted
Interested in nuclear #mechanobiology, and how advanced genomic tools can shed light on how the cell nucleus might sense mechanical forces? Read our latest review by excellent Julien Morival and Anna Hazelwood, now published @J_Cell_Sci:
journals.biologists.com/jcs/…
Edgar R. Gomes @gomeslabo.bsky.social retweeted
Want to learn about MAGIC project's goals and progress in accelerating the development of genetic therapies for muscular dystrophies? 🤔
Get updates straight to your inbox with our newsletter! 📨
Sign up today👉eepurl.com/iCC9E2
ALT Receive updates on accelerating the development of genetic therapies for muscular dystrophies
Edgar R. Gomes @gomeslabo.bsky.social retweeted
We are hiring!
Interested in infection biology, immunology, microbiology?
Funded postdoctoral position in our lab at Institut Pasteur research.pasteur.fr/en/team/…
research.pasteur.fr/en/job/f…
@institutpasteur
@Inserm
Contact us at [email protected]
Edgar R. Gomes @gomeslabo.bsky.social retweeted
MAGIC aims to develop effective treatments for people with rare #MuscularDystrophy.
These rare conditions affect the muscles and can impact walking, eating, sleeping and breathing.
By bringing together leading experts we will push research forwards, faster.🧑🔬
#RareDiseaseDay
ALT A group of members of the MAGIC team
Edgar R. Gomes @gomeslabo.bsky.social retweeted
We are delighted to lead @EU_Commission-funded BIOMICS (coordinated by Nuno and managed by Diana) and partner with @embl (as well as with @CRGenomica and @ETH_en) in advancing biomedical data science and fostering critical thinking. Stay tuned: official launch in January!
EMBL and its partners have received funding from the European Commission for two new Twinning Projects – BIOMICS and FORGENOM II – which will build expertise and research capacity in its member states Portugal and Slovakia, respectively.
Learn more: embl.org/news/connections/sh…
Edgar R. Gomes @gomeslabo.bsky.social retweeted
My lab at UCSF (hsiunglab.org) is looking to recruit multiple postdocs across the spectrum of wet/dry lab interests to contribute to our research in synthetic gene regulation, combinatorial genetics, and tissue biology (including liver biology and immuno-oncology). We esp. welcome individuals who add to our capabilities and perspectives in computation or specific biological domains in tissue biology. Where appropriate there would be exceptional opportunities to work collaboratively with the help of junior specialists in the lab, as well as with other UCSF labs with complementary expertise.
Congrats @Wi_Roman!
>> Growing ‘mini-lungs’ to find treatments to help kids breathe easier: Rhiannon Werder @MCRI_for_kids
>> How do cells work together to create organs?
And what happens when they stop talking? William Roman @ARMI_Labs
Winners of our 2024 #MetcalfPrizes stemcellfoundation.net.au/20…
Edgar R. Gomes @gomeslabo.bsky.social retweeted
>> Growing ‘mini-lungs’ to find treatments to help kids breathe easier: Rhiannon Werder @MCRI_for_kids
>> How do cells work together to create organs?
And what happens when they stop talking? William Roman @ARMI_Labs
Winners of our 2024 #MetcalfPrizes stemcellfoundation.net.au/20…
Excited to see this out!
Myonuclear position and blood vessel organization during skeletal muscle postnatal development
Read this Research Article by Catarina Sequeira @CatarinaSeque11, Lou Martha Wackerbarth, Edgar Gomes @gomes and colleagues @GIMM_Institute @IMMolecular:
journals.biologists.com/dev/…
ALT Figure 1A: Myofiber growth and myonuclear positioning during late embryonic and early postnatal development. (A) Representative images of cross-sectioned gastrocnemius muscle from E17.5, P1, P3, P5, P7 and P20 mice, stained for syntrophin to label the sarcolemma (white) and for DAPI to label nuclei (cyan). Magnifications corresponding to the yellow squares are shown on the right of each image. Individual channels of the magnified views are shown in Fig. S2. Scale bars: 50 µm.
Edgar R. Gomes @gomeslabo.bsky.social retweeted
Myonuclear position and blood vessel organization during skeletal muscle postnatal development
Read this Research Article by Catarina Sequeira @CatarinaSeque11, Lou Martha Wackerbarth, Edgar Gomes @gomes and colleagues @GIMM_Institute @IMMolecular:
journals.biologists.com/dev/…
ALT Figure 1A: Myofiber growth and myonuclear positioning during late embryonic and early postnatal development. (A) Representative images of cross-sectioned gastrocnemius muscle from E17.5, P1, P3, P5, P7 and P20 mice, stained for syntrophin to label the sarcolemma (white) and for DAPI to label nuclei (cyan). Magnifications corresponding to the yellow squares are shown on the right of each image. Individual channels of the magnified views are shown in Fig. S2. Scale bars: 50 µm.
Edgar R. Gomes @gomeslabo.bsky.social retweeted
Today, I reflect on the legacy of @IGCiencia over the last 60 years and what it has meant for research and the scientific community in Portugal and beyond. IGC was never just a place—it was a pioneering model. #IGCLegacyLivesOn 1/5
Edgar R. Gomes @gomeslabo.bsky.social retweeted
We are recruiting a post-doctoral fellow in Melbourne on Tissue engineering and Spatial transcriptomics. Join us!
careers.pageuppeople.com/513…
Edgar R. Gomes @gomeslabo.bsky.social retweeted
New preprint alert 🚨 We're thrilled to share our latest research that unravels the mysteries of t-tubule membrane growth in myofibers💪
biorxiv.org/content/10.1101/…
Thread below ⬇️#scitwitter #CellBiology #myofiber #developmentbiology
Edgar R. Gomes @gomeslabo.bsky.social retweeted
🔵We are seeking a new director!
The Centre for Genomic Regulation (CRG) is an independent research institute located on the shores of the sunny beaches of Barcelona. It is part of the public @iCERCA research system of Catalonia.
We have one clear mission: to understand the complexity of life. We do this to advance knowledge for the health and wellbeing of people, as well as to advance economic prosperity.
🔗Job offer: tinyurl.com/DirectorJO
🔗Full Brochure: tinyurl.com/DirectorBR
