Building the world’s first AI-Driven Digital Organism (AIDO). We're hiring: https://nitter.cf/t.co/JwdGBJvhkL

Palo Alto | Paris | Abu Dhabi
Joined September 2024
Out today in @cellpressnews: "A world model of the virtual cell," from our co-founders @ericxing and @dasongle. Their definition of a virtual cell is a stateful, multi-modal, multi-scale simulator, judged on whether it stays coherent across a sequence of interventions. Open access: cell.com/cell/fulltext/S0092…
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A model that makes one prediction and resets only captures a snapshot. AIDO Cell holds the cell's state: perturb it, read it out, then further experiment on the cell you just changed. @DrugDiscovNews on where the virtual cell came from, what's left to prove and how world models are redefining cellular simulation: drugdiscoverynews.com/what-i…
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1/ AIDO Cell is a simulator for cell biology. You instantiate a virtual cell, perturb it, read out experimental measurements, branch it, and perturb it again. An example of how it works, and what it does and doesn't do -> 🧵
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Today we're releasing a preview of AIDO Cell, a world model of the human cell. It simulates one cell across DNA, RNA, protein, through regulatory networks and whole-cell behavior. Not four models handing results to each other. One system.
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GenBio AI researchers' new Perspective paper in @NatureMedicine lays out a blueprint for a simulator of biology: the AI-Driven Digital Organism (AIDO), a system of integrated multiscale foundation models spanning every scale, from molecules to cells to individuals. Not siloed predictors but a connected, hierarchical system: central-dogma sequence FMs, 2D positional encodings, and differentiable computation graphs propagating information bidirectionally across scales. The endpoint is a world model of biology: condition on a state, apply an intervention, roll out counterfactual trajectories. Read the paper: nature.com/articles/s41591-0…
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Today at 12 pm in #ICML2026 Hall B2: @dasongle’s will present a novel architecture for a virtual cell world model - one that enables simulated cells as an end-to-end platform: from actionable biological prompts to anticipated outcomes at all levels (molecular, structural, interactional, and morphological) in a fully aligned, integrative, multi-modal, and multi-scale fashion. More details: icml.cc/virtual/2026/80215
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Replying to @icmlconf
@icmlconf is the field's leading venue for machine learning research. Next week, GenBio AI will be on-site speaking on virtual cell world models. Where to find us in Seoul, July 6 to 11. All times local. Monday July 6, 4:00 PM, Hall B2 Co-founder and CTO @dasongle presents "A World Model of the Virtual Cell" in the AI for Science Expo Workshop. Monday July 6, 6:30 PM, Hall B2 Le’s panel will break down foundation models and agentic systems for closed-loop discovery. Saturday, July 11, from 8:00 AM, Room 317 Le co-organizes the 3rd Workshop on Multimodal Foundation Models for Life Sciences. Come find the team at #ICML2026
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Months of research compressed into days. That's the promise of virtual cell world models. GenBio AI Co-founder & CTO @dasongle breaks down how we're building them and what it means for drug discovery. Full piece by @jennschenker in @theinnovator here: x.genbio.ai/EI7RMW
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