@genbioai

Building the world’s first AI-Driven Digital Organism (AIDO). We're hiring: https://nitter.cf/t.co/JwdGBJvhkL

 Palo Alto | Paris | Abu Dhabi
genbio.ai/
Joined September 2024
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Today we're releasing a preview of AIDO Cell, a world model of the human cell. It simulates one cell across DNA, RNA, protein, through regulatory networks and whole-cell behavior. Not four models handing results to each other. One system.
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GenBio AI retweeted
Eric Xing
@ericxing
Sep 17
We discussed fundamental issues in the definition, model architecture, computational algorithm, and meaningful evaluation/qualification of a fully steerable virtual cell that is multi-modal, multi-scale, dynamic, and stateful. @dasongle , @genbioai , @mbzuai , @CarnegieMellon cell.com/cell/fulltext/S0092…

A world model of the virtual cell

The virtual cell is envisioned as a multi-modal, multi-scale, and stateful world model that can simulate, perturb, and ultimately program cellular systems. This perspective outlines how this paradigm...

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Out today in @cellpressnews: "A world model of the virtual cell," from our co-founders @ericxing and @dasongle. Their definition of a virtual cell is a stateful, multi-modal, multi-scale simulator, judged on whether it stays coherent across a sequence of interventions. Open access: cell.com/cell/fulltext/S0092…
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A model that makes one prediction and resets only captures a snapshot. AIDO Cell holds the cell's state: perturb it, read it out, then further experiment on the cell you just changed. @DrugDiscovNews on where the virtual cell came from, what's left to prove and how world models are redefining cellular simulation: drugdiscoverynews.com/what-i…
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It’s been a week since we revealed AIDO Cell. Here’s some of the coverage that encapsulates the overall mission and reception (🧵):
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More coverage from @fwpharma, @TLDRnewsletter, @BigDATAwireNews, The Innermost Loop (by @alexwg), and other prominent newsletters across AI and biotech.
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Join the waitlist for early access: genbio.ai/waitlist/

Virtual Cell Platform Waitlist - Genbio AI

Join the waitlist for early access We're looking for partners across academia, biotech, and pharma to help us build a virtual cell bank, expand what AIDO Cell can simulate and extend it to new cell...

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GenBio AI retweeted
SynBioBeta
@SynBioBeta
Aug 26
Replying to @genbioai
@genbioai has released a preview of AIDO Cell—a stateful, multiscale world model designed to simulate cellular responses from DNA and RNA through proteins to whole-cell behavior. Early access for researchers is planned. businesswire.com/news/home/2… Subscribe to our newsletter and get the biggest biotech news straight to your inbox 🧬 syntheticbiologysummit.com/?…
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1/ AIDO Cell is a simulator for cell biology. You instantiate a virtual cell, perturb it, read out experimental measurements, branch it, and perturb it again. An example of how it works, and what it does and doesn't do -> 🧵
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20/ There are benefits and drawbacks to this, but our strategy is to make biology fully differentiable. -> 2. BAIDO Cell currently ships with two prototype cell lines: K-562 and Hep-G2.
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Correction on 20/ that should read "AIDO Cell," not "BAIDO Cell." Apologies for the typo.
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27/ Where it doesn't lead: AlphaGenome on ATAC, DNase and the RNA output tracks, AlphaFold3 on protein-DNA, isoDDE on protein-ligand docking. AIDO Cell is also pushing into territory that no existing model attempts.
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28/ Simulating the multi-scale, layer-spanning dynamics of a cell remains a challenge to both predict and validate. We are actively working to bridge the gap between what is functionally possible and what benchmarks exist in the field. Blog post and full report: genbio.ai/aido-cell-simulato…

AIDO Cell: A General-Purpose Simulator for Cell Biology - Genbio AI

Engineering is the practice of applying rational design frameworks to solve real-world problems. Electrical engineers design circuits for voltage and current, chemical engineers compute kinetics and...

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