Building the future of cell circuits, mom of four ⚽️😻
Toronto
Joined August 2022
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Grace Young retweeted
Oxford Nanopore@nanopore
4hUnited Kingdom!
United KingdomConnected via WebLocation may be affected by a proxy or VPN.Account-level information, not a live location or per-post device.
Antibody development, end-to-end with one solution. Antibody discovery involves screening, confirming and characterising at multiple stages, and nanopore sequencing can support all of them.
See how Pfizer has been applying this across their own workflow: bit.ly/4AlvF4t
Grace Young retweeted
🦠 How does influenza A virus replicate?
A comprehensive review by Toby Carter and Munir Iqbal explores the key stages of the IAV replication cycle and highlights potential areas for developing new antiviral strategies.
mdpi.com/1999-4915/16/2/316
Grace Young retweeted
Last session on Thyroid #ECCyto2026 @EFCS17 @IvanaKholova @MozeticV @IACytology @chriszioga @JM_CytoBox @PapSociety @cytopathology
Grace Young retweeted
The worst moment for a bioinformatician: the data lands in your inbox — wild type vs. mutant, one sample each — and it's already too late.
Without biological replicates, there's no analysis to run.
Grace Young retweeted
KU Leuven researchers review a new generation of broader spectrum antivirals.
Conserved viral polymerases may let one drug hit multiple RNA virus families, with combinations offering even wider coverage and stronger resistance barriers.
nature.com/articles/s41579-0…
Grace Young retweeted
Tissue-specific aging—a new paradigm based on transcriptional insights from select model systems and humans
frontiersin.org/journals/gen…
hiPSC-derived neural crest-osteoprogenitor & transgenic🐭modeling of structural/copy-number variants for #Craniosynostosis
Roles of FGF5 [dup(4)(q21.21), 730kb ▶️a neoTAD] & FGF9 [interspersed 13q12.11 duplication, 568 kb] (-/+FOXP2)
Hi-C, deepC & Focused transcript analysis surrounding duplicated regions (-/+2 Mb)
@DagmaraKorona @GIMJournal 2026
sciencedirect.com/science/ar…
Grace Young retweeted
I can imagine a world where cell therapy enables optogenetic applications for rhythm management
Grace Young retweeted
How cells increase energy production to meet the demands of force response is incompletely understood. Dawson et al. suggest that the muscle isoform of the glycolytic enzyme phosphofructokinase is recruited to #actin, thereby serving this important role. hubs.la/Q04z9jy00
Grace Young retweeted
In the latest issue! Acanthamoeba ATP synthase structure reveals the TCA cycle is tethered to OXPHOS dlvr.it/TVnFJS
Grace Young retweeted
Just weeks after IntraBio secured a label expansion for its lead asset Aqneursa, Japanese drugmaker Shionogi is moving in to take the reins. fiercepharma.com/pharma/shio…
Grace Young retweeted
BI-TfR1 CapX rapidly transits the blood-brain barrier for efficient, low-dose gene delivery throughout the CNS
An engineered TfR1 capsid reaches the brain within minutes and transduces most cortical and spinal neurons at low intravenous dose
biorxiv.org/content/10.64898…
Grace Young retweeted
Cerebral microthrombi promote focal Cav-1-dependent blood-brain barrier impairment, triggering neuroinflammation and neuronal damage after traumatic brain injury
biorxiv.org/content/10.64898…
Our next DevBioConnect Author Seminar is on October 14th, 2026, 12:00–1:00 PM EST
Dr. Heer Joisher
On Chick🐥 Retina photoreceptor patterning
sciencedirect.com/science/ar…
Dr. Nathan Anderson
On Drosophila🪰 Neuronal lineage specification
sciencedirect.com/science/ar…
Register here👇
forms.gle/oPAyTEnRU8NyrBKR7
@Dev_Bio_Journal @SocDevBio
Grace Young retweeted
Malignant oesophageal stricture with airway involvement: who needs a dual stent?
New @FrontlineGastro study (n=26): an oesophageal stent placed first worsened airway narrowing in 1 in 3, and fistulas were often unexpected. The authors propose a first treatment algorithm 🫁
Read the full paper here:
fg.bmj.com/content/flgastro/…
@BritSocGastro @my_UEG @AmCollegeGastro @DDWMeeting @ESGE_news @dr_aditi_kumar @OTavabie @DrJMKennedy @DunnePdj @TrevorTabone @eathar_s @IrenePerezMD @KGananandan @zare_benjamin @dtleiberman
Grace Young retweeted
🧬Hear from a leading expert in #proteomics research!
We are excited to announce that Dr. Bruno Manadas (University of Coimbra, Portugal) would be presenting and sharing his insights as invited speaker at #ISFMS2027!
🔗Submit your abstract here:
sciforum.net/event/ISFMS2027…
Grace Young retweeted
AI IS STARTING TO CHANGE HOW SCIENCE IS DONE.
Anthropic researcher and physicist Matthew Schwartz explored how Claude can work alongside scientists to solve problems across different fields.
He calls them “Claude-shaped” problems, meaning scientific problems that fit AI’s strengths in coding, mathematics, data analysis and connecting knowledge across disciplines.
The results are fascinating:
> 400+ scientific problems explored
> 36 manuscripts across 18 fields
> 5.7 BILLION pairs of genetic mutations analyzed
> 4,452 economics papers examined
> 6,072 languages included in a linguistics database
> 30 difficult Feynman integrals calculated, including 15 previously uncomputed
In ecology, Claude also helped solve a long standing computational problem and found that forest composition in Panama changed about 4.5× faster than predicted by neutral biodiversity theory.
But humans still played the crucial role of deciding what the results actually meant.
This could be the beginning of a new scientific workflow:
Human intuition → AI exploration → computation → discovery → human validation.
It can give scientists the ability to explore thousands of ideas at a scale humans could never manage alone 🔥
Anthropic@AnthropicAIUnited States
United StatesConnected via WebAccount-level information, not a live location or per-post device.
In physics, an “impedance mismatch” occurs when two systems each work well but are poorly matched.
In this Science Blog guest post, Harvard physicist Matthew Schwartz argues that something similar is happening with AI and science. LLMs are capable at many things, but working with them as you would with a human collaborator isn’t currently the best way to elicit their scientific strengths.
To address this mismatch, Schwartz created a toolkit for exact calculations in quantitative science. Because similar calculations often emerge in very different areas of science, Claude found connections to ecology, population genetics, and a dozen other fields, and Schwartz worked with domain experts to steer it towards interesting questions.
Read more about these projects here: anthropic.com/research/claud…
Grace Young retweeted
🗞️ A @FDA NDA submission has been initiated for zipalertinib plus platinum-based chemotherapy in frontline, EGFR exon 20 insertion–positive NSCLC #lcsm #oncology
Dive into the REZILIENT3 data supporting the application: onclive.com/view/nda-submiss…
BMO Capital Markets is more impressed by Merck’s plans to replace lost Keytruda revenue than on Bristol Myers Squibb’s efforts to fill the expected void that will come from loss of exclusivity for both Opdivo and Eliquis.
hubs.ly/Q04z28Zx0
