Building the future of cell circuits, mom of four ⚽️😻
Toronto
Joined August 2022
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- Following213
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Grace Young retweeted
Just weeks after IntraBio secured a label expansion for its lead asset Aqneursa, Japanese drugmaker Shionogi is moving in to take the reins. fiercepharma.com/pharma/shio…
Grace Young retweeted
BI-TfR1 CapX rapidly transits the blood-brain barrier for efficient, low-dose gene delivery throughout the CNS
An engineered TfR1 capsid reaches the brain within minutes and transduces most cortical and spinal neurons at low intravenous dose
biorxiv.org/content/10.64898…
Grace Young retweeted
Cerebral microthrombi promote focal Cav-1-dependent blood-brain barrier impairment, triggering neuroinflammation and neuronal damage after traumatic brain injury
biorxiv.org/content/10.64898…
Our next DevBioConnect Author Seminar is on October 14th, 2026, 12:00–1:00 PM EST
Dr. Heer Joisher
On Chick🐥 Retina photoreceptor patterning
sciencedirect.com/science/ar…
Dr. Nathan Anderson
On Drosophila🪰 Neuronal lineage specification
sciencedirect.com/science/ar…
Register here👇
forms.gle/oPAyTEnRU8NyrBKR7
@Dev_Bio_Journal @SocDevBio
Grace Young retweeted
Malignant oesophageal stricture with airway involvement: who needs a dual stent?
New @FrontlineGastro study (n=26): an oesophageal stent placed first worsened airway narrowing in 1 in 3, and fistulas were often unexpected. The authors propose a first treatment algorithm 🫁
Read the full paper here:
fg.bmj.com/content/flgastro/…
@BritSocGastro @my_UEG @AmCollegeGastro @DDWMeeting @ESGE_news @dr_aditi_kumar @OTavabie @DrJMKennedy @DunnePdj @TrevorTabone @eathar_s @IrenePerezMD @KGananandan @zare_benjamin @dtleiberman
Grace Young retweeted
🧬Hear from a leading expert in #proteomics research!
We are excited to announce that Dr. Bruno Manadas (University of Coimbra, Portugal) would be presenting and sharing his insights as invited speaker at #ISFMS2027!
🔗Submit your abstract here:
sciforum.net/event/ISFMS2027…
Grace Young retweeted
AI IS STARTING TO CHANGE HOW SCIENCE IS DONE.
Anthropic researcher and physicist Matthew Schwartz explored how Claude can work alongside scientists to solve problems across different fields.
He calls them “Claude-shaped” problems, meaning scientific problems that fit AI’s strengths in coding, mathematics, data analysis and connecting knowledge across disciplines.
The results are fascinating:
> 400+ scientific problems explored
> 36 manuscripts across 18 fields
> 5.7 BILLION pairs of genetic mutations analyzed
> 4,452 economics papers examined
> 6,072 languages included in a linguistics database
> 30 difficult Feynman integrals calculated, including 15 previously uncomputed
In ecology, Claude also helped solve a long standing computational problem and found that forest composition in Panama changed about 4.5× faster than predicted by neutral biodiversity theory.
But humans still played the crucial role of deciding what the results actually meant.
This could be the beginning of a new scientific workflow:
Human intuition → AI exploration → computation → discovery → human validation.
It can give scientists the ability to explore thousands of ideas at a scale humans could never manage alone 🔥
In physics, an “impedance mismatch” occurs when two systems each work well but are poorly matched.
In this Science Blog guest post, Harvard physicist Matthew Schwartz argues that something similar is happening with AI and science. LLMs are capable at many things, but working with them as you would with a human collaborator isn’t currently the best way to elicit their scientific strengths.
To address this mismatch, Schwartz created a toolkit for exact calculations in quantitative science. Because similar calculations often emerge in very different areas of science, Claude found connections to ecology, population genetics, and a dozen other fields, and Schwartz worked with domain experts to steer it towards interesting questions.
Read more about these projects here: anthropic.com/research/claud…
Grace Young retweeted
🗞️ A @FDA NDA submission has been initiated for zipalertinib plus platinum-based chemotherapy in frontline, EGFR exon 20 insertion–positive NSCLC #lcsm #oncology
Dive into the REZILIENT3 data supporting the application: onclive.com/view/nda-submiss…
BMO Capital Markets is more impressed by Merck’s plans to replace lost Keytruda revenue than on Bristol Myers Squibb’s efforts to fill the expected void that will come from loss of exclusivity for both Opdivo and Eliquis.
hubs.ly/Q04z28Zx0
Grace Young retweeted
Humans are ingesting so much AI content that prompt language, fawning feedback and “caveman speak” are officially bleeding into real-world meetings. on.wsj.com/3TfCzaP
Most wellness trends aren’t wrong: They’re just not always worth it healthydebate.ca/2026/09/abo… via @HealthyDebate & #TaraMoroz
Grace Young retweeted
#HCC’s lipid addiction fuels tumor progression, but its regulatory drivers remain unclear.
This study reveals the E2F1/LRRC1/FASN axis as a key regulator of lipid reprogramming, tumor growth and metastasis. @ZJU_China
#GenesAndDiseases: doi.org/10.1016/j.gendis.202…
Grace Young retweeted
Rare cancers together account for nearly 1 in 4 cancer diagnoses in Europe.
We recognize the patients, researchers, and healthcare professionals advancing clinical research and expanding treatment options where unmet needs remain greatest.
Rare should never mean overlooked.
Grace Young retweeted
A confident answer isn't the same as a correct one. Matthew Kurian, MD, discusses automation bias, the tendency to accept AI output at face value, and why trainees and clinicians should verify before they trust, especially when new data may not be published yet.
🎙️Listen to the latest episode of #BreastCancerBriefing: hubs.li/Q04yL_Zl0
Grace Young retweeted
LBC: Chronic illness cases surge post-covid, leaving young patients searching for answers
'Diagnoses of a chronic condition..have risen five-fold since the COVID-19 pandemic began, according to experts..Postural Orthostatic Tachycardia Syndrome (POTS)..'
lbc.co.uk/article/chronic-il…
Grace Young retweeted
Does the flu shot protect more than your lungs?
New episode of The Heart of Prevention: Dr. Keerthana Pakanati @Kpakanati3 sits down with Dr. Alison Bailey @a_l_bailey to unpack the growing link between influenza and cardiovascular disease, including what the cardiovascular analysis of FLUNITY-HD reveals about heart failure hospitalization risk.
They dig into where flu vaccination might fit alongside statins and antihypertensives in the preventive cardiology toolkit, how to think about high-dose vs. standard-dose vaccination in older adults, and what evidence gaps remain.
Listen now: art19.com/shows/the-heart-of…
@SanofiUS provided financial sponsorship for the production of this podcast and had no influence or involvement in the review, approval, or development of any content.
#PreventiveCardiology #Cardiology #InfluenzaVaccine #HeartHealth
Grace Young retweeted
More evidence that #ClonalHematopoiesis evolution is context dependent! 🧬 Clonal selection reflects both cancer therapy and germline genetics, with important implications for tMN development.
Huge congrats to @KellyLBolton @IrenaeusChan & colleagues!
nature.com/articles/s41588-0…
Grace Young retweeted
Aptadir has €40M war chest to advance demethylating medicines firstwordpharma.com/story/81…
Grace Young retweeted
This article featuring @ShrillaB is a great reminder of how women's cardiac symptoms differ.
This #WorldHeartDay, commit to being a better ally and advocate for women with heart disease.
#WomensHeartHealth #WomenInCardiology #WomensHealth
Heart disease is responsible for 35 per cent of all deaths in women every year, yet the condition can often go unrecognised in female patients.
One cardiologist explains why and shares five warning signs to watch out for 👇
telegraph.co.uk/health-fitne…
