Jack of all trades, master of none. PostDoctoral Researcher in Computational Biology at @Rakyan_lab. Now @franrodalg.bsky.social
London, The Earth
Joined October 2011
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New paper alert! The RNA ribosomal components are so essential that they appear as tons of back to back copies in the genome, which makes them really hard to analyse, so have been mostly ignored. But does it matter how many copies one has? A thread (1/9)
cell.com/cell-genomics/fullt…
In case anyone cares, I'm not going to post here anymore. I will see how long I keep the acount active just in case, but from now on I'll see you where skies are bluer.
Fran Rodriguez-Algarra retweeted
🚨New Review🚨 We've recently seen huge advances in our understanding of de novo DNA methyltransferase function. @WillowRolls and @mdrwilson and I have written a mini-review on what human disease mutations told us:
doi.org/10.1042/BST20231017
#Epigenetics #Epigenomics 🧵 1/2
Fran Rodriguez-Algarra retweeted
We present Single Myofiber Protein Function-Omics, a novel approach that enables the inspection of underlying proteome landscape, coupled with protein functionality - with all data derived from the exact same single SkM cell... #myotwitter
biorxiv.org/content/10.1101/…
Fran Rodriguez-Algarra retweeted
We have put together an exceptional scientific programme for the @GenSocUK #Epigenetics2025 meeting to be held in Belfast. Are you interested in disease mechanisms and love epigenetics? Register here: REGISTER ONLINE: my.genetics.org.uk/item.php?….
Fran Rodriguez-Algarra retweeted
interested in 3D genome organization during early development? want to understand how it is shaped by RNA? you like data analysis and developing new computational tools? 🧬💻🧐
With @golobor we are recruiting a PhD student/intern to work with us at @IMBA_Vienna
Fran Rodriguez-Algarra retweeted
📢Job opening: Research Assistant / Postdoctoral Research Assistant in music information research @c4dm @QMEECS on a project funded by @innovateuk
Closing date: 31 August 2024 - more info: qmul-jobs.tal.net/vx/mobile-…
Fran Rodriguez-Algarra retweeted
Francisco Rodriguez-Algara on ribosomal DNA copy number #genomescienceUK
Fran Rodriguez-Algarra retweeted
Don't miss this seminar by a Bivalent chromatin expert Phillip Voigt, it will be all about Bivalency and mechanisms of transcriptional poising @blizard_inst and online
Reminder about tomorrow's @QMULepigenetics seminar by Philipp Voigt (Babraham Institute). Title "Decoding Bivalency: Mechanisms of Poising at Bivalent Gene Promoters" 28th June, 15:30 BST in person at @blizard_inst or online qmulepigenetics.com/webinars
Fran Rodriguez-Algarra retweeted
Reminder about tomorrow's @QMULepigenetics seminar by Philipp Voigt (Babraham Institute). Title "Decoding Bivalency: Mechanisms of Poising at Bivalent Gene Promoters" 28th June, 15:30 BST in person at @blizard_inst or online qmulepigenetics.com/webinars
Fran Rodriguez-Algarra retweeted
Join my team at @kingsmnd @KingsIoPPN for a unique opportunity as a Research Fellow in #Epigenetics!
Be part of an exciting project: Validate new treatment targets for ALS/MND by evaluating methylation targets. Collaborate with biologists on wet lab experiments. Plus, work alongside @AmmarAlChalabi @AlfredoIacoange
Closing date: July 17, 2024. 🧠⚡🧬 #Epigenetics #ALS #neuroscience
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Fran Rodriguez-Algarra retweeted
You are pleased to announce that Philipp Voigt (Babraham Institute) will speak at the @QMULepigenetics seminar series. Title "Decoding Bivalency: Mechanisms of Poising at Bivalent Gene Promoters" 28th June, 15:30 BST in person at @blizard_inst or online qmulepigenetics.com/webinars
Fran Rodriguez-Algarra retweeted
Latest on ribosomal DNA. Another big collaborative effort!
Ribosomal DNA copy number is associated with body mass in humans and other mammals | Nature Communications nature.com/articles/s41467-0…
This Sunday, June 2nd, I'll be at #eshg2024 in Berlin presenting poster about this. If you're around and want to have a chat, come see me at poster P17.072.A! Feedback extremely welcome ☺️☺️
New paper alert! The RNA ribosomal components are so essential that they appear as tons of back to back copies in the genome, which makes them really hard to analyse, so have been mostly ignored. But does it matter how many copies one has? A thread (1/9)
cell.com/cell-genomics/fullt…
Fran Rodriguez-Algarra retweeted
QMUL Epigenetics 'Design a Logo' competition!
We are relaunching as the QMUL Centre for Epigenetics. Design a new logo for us & win a £250 prize! All details 👉qmulepigenetics.com/logocomp Deadline is 6pm GMT, June 6, 2024 and the competition is open to all. please RT
Fran Rodriguez-Algarra retweeted
"Dear Editor,
I have incorporated all suggestions from reviewer 2, and I hope you find the changes an improvement to the manuscript as a whole."
Fran Rodriguez-Algarra retweeted
🎉Congratulations to the @Rakyan_lab ! @RosetreesT is proud to have supported this exciting work! 🎉
New research in @CellGenomics led by @Rakyan_lab, @evans1_d and collaborator @evans1_d suggests that people with more copies of ribosomal DNA have higher risks of developing disease. Research funded by @Barts_Charity, @RosetreesT and @BBSRC. Find out more: qmul.ac.uk/media/news/2024/f…
Forgot to say I'll be at the @Londonomics_net symposium this next Monday (May, 20th) giving a short talk about this work, in case you want to chat about it :)
New paper alert! The RNA ribosomal components are so essential that they appear as tons of back to back copies in the genome, which makes them really hard to analyse, so have been mostly ignored. But does it matter how many copies one has? A thread (1/9)
cell.com/cell-genomics/fullt…
Thrilled to see our recent @CellGenomics paper on rDNA CN consequences in the @uk_biobank is getting some press coverage! With quotes from Vardhman (@Rakyan_lab) and Dave (@evans1_d) 👌
medicalxpress.com/news/2024-…
Fran Rodriguez-Algarra retweeted
Research led by @QMUL suggests that people with more copies of #rDNA have higher risks of developing inflammation and diseases during their lifetimes. qmul.ac.uk/media/news/2024/f…
ALT DNA
Fran Rodriguez-Algarra retweeted
Ribosomal DNA Copy Number Levels Linked to Kidney Function, Inflammation in UK Biobank genomeweb.com/sequencing/rib…