Scientist developing mass spectrometry technologies to study proteins and small molecules @UKJ_Jena.
Joined February 2019
- Tweets700
- Following982
- Followers1.8K
- Likes1.5K
Florian Meier retweeted
Are you interested to learn more about the circulating blood proteome? If so, here's a review that covers new and emerging technologies, advances, challenges, proteoforms, vesicles, protein networks, antibodies, and microsamples. @hupo_org
pubs.acs.org/doi/10.1021/acs…
Florian Meier retweeted
This is great! @NIAIDNews have launched a collection of public domain illustrations (currently 550 individual icons) bioart.niaid.nih.gov/
Florian Meier retweeted
What if you could use #AI to find and accurately excise the culprit cells, quantify >5,000 proteins in each, and find a cure for a life-threatening disease that has no effective treatment?
That's the beginning of spatial medicine, a momentous medical advance.
In the new Ground Truths
Because X auto-suppresses the link, you can find it in my profile
Florian Meier retweeted
Today we report in @NatureGenet the genetic landscape of cancer drug resistance mechanisms from CRISPR base editing screens
nature.com/articles/s41588-0…
Florian Meier retweeted
Introducing our new study @ Tissue-PPT, an Extensive Atlas of Proteome and Phosphoproteome Turnover across mouse tissues and brain regions. biorxiv.org/content/10.1101/… @Yanshen73854711 @JunminPengLab @euforna #Proteomics #TeamMassSpec #Proteinturnover
Florian Meier retweeted
A biomedical first: spatial biology used to find a lifesaving treatment!
Just published @Nature
Deep visual proteomics with #AI leads to effective JAKI treatment for 7 patients with toxic epidermal necrolysis
nature.com/articles/s41586-0… @labs_mann @NordmannThierry
Florian Meier retweeted
Can a deadly rash be cured by repurposing drugs? Our @Nature paper says yes! Deep Visual Proteomics reveals JAK inhibitors as potential TEN treatment. A game-changer in #dermatology & #SpatialProteomics.
Congratulations to all!
@NordmannThierry's tweetorial explains below:
Published today! Spatial proteomics reveals JAK/STAT as a target for Toxic Epidermal Necrolysis, an often fatal skin reaction to common medication. We validated our findings in pre-clinical models & successfully treated the first patients worldwide.🧵⬇️ nature.com/articles/s41586-0…
Florian Meier retweeted
Finally out! EXCRETE, our MS workflow for high throughout microbial exoproteomics with a focus here on cyanobacteria 🦠
nature.com/articles/s42003-0…
very excited to share my recent collab with @SynBioJazz, @fmeierX, @oliinyk_denys. Here we take a deep dive into the exoproteome of cyanobacteria with our MS workflow EXCRETE. It’s fast, cheap and only needs a couple of hundred microlitres. Take a look:
biorxiv.org/cgi/content/shor…
Florian Meier retweeted
#Genome of #Greenland #shark #decoded ‼️
An international team of #scientists, including Steve Hoffmann and @Alessan82703458 from the @LeibnizFLI, has mapped this Shark’s genome.
👉More information: bit.ly/4gkAGA8
👉bit.ly/3B0csek
Florian Meier retweeted
Wir zeigen Gesicht: Ca. 500 Beschäftigte und Studis aus verschiedensten Bereichen 🏥⚕️🦷🧪🔬👨🎓💻🧑🔧 setzten gestern ein Zeichen für ein weltoffenes #Thüringen, denn das brauchen wir für unsere Arbeit in Wissenschaft und Patientenversorgung! #thueringenweltoffen @jenalichtstadt
Florian Meier retweeted
Beyond protein lists: AI-assisted interpretation of proteomic investigations in the context of evolving scientific knowledge nature.com/articles/s41592-0…
---
#proteomics #prot-paper
Florian Meier retweeted
The analysis of the cancer that is still trying to kill me.
One patient, four organs, many insights: We applied Deep Visual Proteomics to track protein changes in Signet Ring Cell Carcinoma. This spatial analysis could pave the way for more targeted therapies in rare tumors #PrecisionOncology #DeepVisualProteomics
doi.org/10.1101/2024.08.07.6…
Florian Meier retweeted
Very nice to see the result of my internship at @genentech out in @biorxivpreprint! If you’re intersted in diaPASEF and immunopeptidomics, check this out:
biorxiv.org/content/10.1101/…. Big thanks to @susanklaeger and @CMichaelRose for introducing me to immunopeptidomics!
Florian Meier retweeted
High-throughput low-input mass spectrometry #phosphoproteomics method uPhos from @fmeierX lab utilizes a plate-based workflow and is applied to a drug response screen and mouse brain to highlight its sensitivity and selectivity ➡️embopress.org/doi/full/10.10…
Thrilled to share that our µPhos paper led by @oliinyk_denys is out in @MolSystBiol. We teamed up with @SeanJHumphrey to facilitate large-scale phosphoproteomics and sample-limited applications without the need for specialized equipment embopress.org/doi/full/10.10…
Florian Meier retweeted
Thrilled to see our paper "A Proximity Proteomics Pipeline with Improved Reproducibility and Throughput" published! It describes the automated enrichment of biotinylated proteins in a 96-well plate format for spatial proteomics and protein interactions.
embopress.org/doi/full/10.10…
Florian Meier retweeted
Thrilled to finally see µPhos published in @MolSystBiol! A big thank you to @fmeierX, @SeanJHumphrey and all other coauthors for this exciting journey! Check out our greatly improved and extended story on how to unlock the true power of phosphoproteomics: embopress.org/doi/full/10.10…
Florian Meier retweeted
‼️ We are hiring: Two postdoc positions and one PhD student position are available in my group @UniHalle in the new SFB1664! 🥳The topic will be on doing cool stuff with crosslinking MS of plant proteins. snp2prot.uni-halle.de/positi…
Please RT!
Erfolg für die Protein- & Pflanzenforschung an der MLU: Die @dfg_public fördert den neuen Sonderforschungsbereich "Plant Proteoform Diversity".👏 Beteiligt sind auch @LeibnizIPK, @IPB_Halle @UniLeipzig. Designierter Sprecher ist MLU-Prof. Dr. Marcel Quint. mlu.de/7i2zt
ALT Pflanzenwissenschaftler und SFB-Sprecher Marcel Quint betrachtet Keimlinge in einer Petrischale.
Florian Meier retweeted
In the latest issue! Global, site-resolved analysis of ubiquitylation occupancy and turnover rate reveals systems properties dlvr.it/T7JWzD
Florian Meier retweeted
We are delighted to share the #tyrosine @KinaseLibrary, now in @Nature: nature.com/articles/s41586-0…
Tyrosine predictions and enrichment analysis are now available: kinase-library.phosphosite.o…
#TheKinaseLibrary #KL #part2
🧵
1/9
