Fengwei YU (@fengwei_yu) header
Fengwei YU (@fengwei_yu) profile picture

Fengwei YU

@fengwei_yu

Distinguished TLL Investigator @Temasek LifeSciences Laboratory, NUS, Singapore. #cellbiology #dendritepruning #neurodegenerativediseases #Drosophila

 West Region, Singapore
Joined October 2018
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  • Followers134
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Photo by Fengwei YU (@fengwei_yu)Photo by Fengwei YU (@fengwei_yu)Photo by Fengwei YU (@fengwei_yu)
Our first manuscript on mammalian development is now on @biorxivpreprint! Arl2 Associates with Cdk5rap2 to Regulate Cortical Development via Microtubule Organization. Took us 8 years from the initial findings on fly Arl2 to its mammalian homolog. biorxiv.org/content/10.1101/…
Arl2 Associates with Cdk5rap2 to Regulate Cortical Development via Microtubule Organization

Arl2 Associates with Cdk5rap2 to Regulate Cortical Development via Microtubule Organization

ADP ribosylation factor-like GTPase 2 (Arl2) is crucial for controlling mitochondrial fusion and microtubule assembly in various organisms. Arl2 regulates the asymmetric division of neural stem cells...

biorxiv.org
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Excited to share that my 50th paper is out @PLOSBiology! Tumor suppressor #Parafibromin directly regulates the expression of polo and aurora-A in neural stem cells! Kudos to our talented team members and collaborators! @qiannandeng0520 journals.plos.org/plosbiolog…
Parafibromin governs cell polarity and centrosome assembly in Drosophila neural stem cells

Parafibromin governs cell polarity and centrosome assembly in Drosophila neural stem cells

This study shows that the conserved tumor suppressor Parafibromin plays an important role in Drosophila neural stem cell function, regulating the expression of the centrosomal proteins Polo and AurA,...

journals.plos.org
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Our latest work on acentrosomal microtubules in quiescent neural stem cells is published in @embojournal！ embopress.org/doi/full/10.15… @qiannandeng0520 @sing21410089
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I hope this article about myself will inspire young scientists especially girls/women to pursue their passion for science! A huge thank you to Nicole, Tano, @SPOREMOHAN @qiannandeng0520 @mahekta, other friends and my lovely team! duke-nus.edu.sg/medicus/2021…
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Upcoming exciting seminar by Fumio Motegi on PAR polarity and asymmetric division! @phil1pingham @HongyanWang9 @TimESaunders @NSCRL_NNI @dmvirshup @MonteiroLab @RayintheRedDot @Yusuke_Toyama @MiaoYansong @fengwei_yu @_JSDB_
Image from Society of Developmental Biologists Singapore (@devbio_sg)
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A new preprint from our lab, hard work by @UrkodC and @RozNorkett biorxiv.org/content/10.1101/…
Ataxin-2 is essential for neurodevelopment in Drosophila and is a major regulator of the cytoskel...

Ataxin-2 is essential for neurodevelopment in Drosophila and is a major regulator of the cytoskel...

Ataxin-2 (Atx2) is a highly conserved RNA binding protein. Atx2 undergoes polyglutamine expansion leading to Amyotrophic Lateral Sclerosis (ALS) or Spinocerebellar Ataxia (SCA). However, the normal...

biorxiv.org
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Fengwei YU retweeted
JSDB (@_JSDB_) profile picture
JSDB
@_JSDB_19 Nov 2020
JSDB/APDBN will have an on-line meeting "RNA, Technology, and Development". Registration fee is free for JSDB members, and JSDB membership is free for students for the first year. Let's join us with this opportunity! jsdb-meeting2021.com/
Image from JSDB (@_JSDB_)
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My talk on modelling neurodevelopmental disorders in flies at the Australian Developmental Neuroscience Forum (ADNF) is on YouTube at youtu.be/jkf1HgRQqi4
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The father of cell biology-Joseph Gall. Here is the website with the full retirement symposium. emb.carnegiescience.edu/news…
Society for Developmental Biology (@SocDevBio) profile pictureSociety for Developmental Biology@SocDevBio19 Nov 2020
Congrats to SDB Lifetime Achievement Awardee Joseph Gall on retirement from @carnegiescience at 92! The Lasker Awardee was a seminal contributor to field of chromosome structure & function, inventor of in situ hybridization & advocate for women in science. youtu.be/Gsb4MJ4YdoI
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The Asia-Pacific Drosophila Research Conference 6 #apdrc is postponed to 3-6th 2023! We hope to meet everyone in person in Singapore! @Yusuke_Toyama @TimESaunders @fengwei_yu @apdrc5
Image from Hongyan Wang (@HongyanWang9)
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First time attending Australian Fly meeting #AusFly2020 (virtual) as keynote speaker. Really exciting to see all Australian colleagues in the meeting!
Image from Hongyan Wang (@HongyanWang9)
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Fengwei YU retweeted
Yimin Zou (@yiminzounew) profile picture
Yimin Zou@yiminzounew9 Jun 2020
meetings.cshl.edu/meetings.a…
Molecular Mechanisms of Neuronal Connectivity (Virtual)

Molecular Mechanisms of Neuronal Connectivity (Virtual)

Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.

meetings.cshl.edu
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See you all!
Yimin Zou (@yiminzounew) profile pictureYimin Zou@yiminzounew9 Jun 2020
meetings.cshl.edu/meetings.a…
Molecular Mechanisms of Neuronal Connectivity (Virtual)

Molecular Mechanisms of Neuronal Connectivity (Virtual)

Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.

meetings.cshl.edu
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Congrats Thomas!
TLecuitLab (@LecuitLab) profile pictureTLecuitLab@LecuitLab2 Jun 2020
Our newly published paper by @BDehapiot et al is now out in @NatureCellBio. The Formin Frl/Fmnl regulates cell deformability during epithelial morphogenesis. A persistent actin network tunes the range of deformations induced by pulsatile contractions. nature.com/articles/s41556-0…
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New manuscript from @HippenmeyerLab @ISTAustria illustrating MADM resource for single cell genetic mosaic analysis of >96% of the entire mouse genome. Besides proof of principle we also revealed non-random mitotic sister chromatid segregation in distinct cell lineages in vivo.
bioRxiv (@biorxivpreprint) profile picturebioRxiv@biorxivpreprint6 Jun 2020
A Genome-wide Library of MADM Mice for Single-Cell Genetic Mosaic Analysis biorxiv.org/cgi/content/shor… #bioRxiv
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Congratulations, Urko! It is so nice to see the paper published!
Urko del Castillo (@UrkodC) profile pictureUrko del Castillo@UrkodC19 May 2020
So happy to see our work finally published in PNAS: Kinetochore protein Spindly controls microtubule polarity in Drosophila axons pnas.org/content/early/2020/…
Image from Urko del Castillo (@UrkodC)
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Check out our latest preprint on the role of Dpr12 and DIP-delta in regulating the wiring between ɣ-KCs and DANs as well as the formation of axonal compartments. biorxiv.org/content/10.1101/…
Transneuronal interactions facilitate axonal compartment formation

Transneuronal interactions facilitate axonal compartment formation

Precise connectivity of neurites to subcellular domains is a conserved feature of complex circuits, but the mechanisms defining precise wiring are largely unknown. The Drosophila mushroom-body is...

biorxiv.org
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Excited to share our review article on neural stem cell reactivation published in @plosgenetics: journals.plos.org/plosgeneti… @Huang90J

Waking up quiescent neural stem cells: Molecular mechanisms and implications in neurodevelopmental...

Neural stem cells (NSCs) are crucial for development, regeneration, and repair of the nervous system. Most NSCs in mammalian adult brains are quiescent, but in response to extrinsic stimuli, they can...

journals.plos.org
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Covid-19 circuit breaker to be extended by one month to June 1: PM Lee straitstimes.com/politics/pr…
Covid-19 circuit breaker to be extended by one month to June 1: PM Lee

Covid-19 circuit breaker to be extended by one month to June 1: PM Lee

He called on all Singaporeans to stay home as far as possible, and urged those who have to go out to do so alone and not as a group or with family. Read more at straitstimes.com.

straitstimes.com
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Another one-month lockdown in Singapore . Hope to contain the virus spreading as soon as possible. Everything goes back to normal soon. 💪Singapore！
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