Assistant Professor, Serra Húnter Fellow, at @Farmacia_UB @UniBarcelona. Formerly in @ChemCambridge, @UoDCeTPD and @uOttawa
Barcelona, Spain
Joined March 2019
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F. Javier Pérez-Areales retweeted
Check out our new paper, "Towards a glutathione-cleavable azobenzene linker for antibody–drug conjugates"
pubs.rsc.org/en/content/arti…
F. Javier Pérez-Areales retweeted
Are you #IBUB?
We look forward to seeing you at the 𝟭𝘀𝘁 𝗜𝗕𝗨𝗕 𝗘𝗮𝗿𝗹𝘆 𝗖𝗮𝗿𝗲𝗲𝗿 𝗗𝗮𝘆.
👉Information: ub.edu/ibub/1st-ibub-early-c…
F. Javier Pérez-Areales retweeted
I am thrilled to share that our story on Intramolecular Bivalent Glues has now been published in @Nature. This has been an incredible team effort alongside my co-leads Matthias Hinterndorfer and Angus Cowan, with the support and guidance from @georg_e_winter and @alessiociulli.
F. Javier Pérez-Areales retweeted
📢#SEQT_articles
Red-light modulated ortho-chloro azobenzene photoswitch for peptide stapling via aromatic substitution and its application for the inhibition of MDM2/p53 interaction as a proof-of-concept
Authors: @dr_illo @SpringGroupChem
🔗pubs.rsc.org/en/content/arti…
F. Javier Pérez-Areales retweeted
🚨 We are hiring a Chemist for the @AlessioCiulli/@Boehringer team at CeTPD.
Join our dynamic drug discovery team and help us find effective PROTACs for oncology targets.
Find out if you'd be right for this position and apply at buff.ly/3K3P5ST
#ChemJobs
ALT Qing, from CeTPD, working at her fume hood
F. Javier Pérez-Areales retweeted
We have enjoyed a wonderful day celebrating 20 years of the Spring Group! 🥂 Big thank you to all of the speakers, alumni and current members for a day filled with science and fond memories! 🧪
F. Javier Pérez-Areales retweeted
📢#MedChemJobs
Contrato Postdoctoral - 17 meses
Descubrimiento de nuevos antimaláricos
Síntesis química en el grupo del Dr. Diego Muñoz-Torrero y estudios biológicos en el grupo del Dr. Xavier Fernández-Busquets del IBEC/ISGlobal.
📆Febrero 2023
🔗ibecbarcelona.eu/postdoctora…
Well done and congrats @RaduNicolescu4 !!! Just the first of many to come!! 🙌🏻 Thank you also to our collaborators from @UniOfSurrey
Hybrid Androgen Receptor Inhibitors Outperform Enzalutamide and EPI-001 in in vitro Models of Prostate Cancer Drug Resistance (Asim, Spring) @RaduNicolescu4; @SpringGroupChem; @dr_illo #openaccess onlinelibrary.wiley.com/doi/…
F. Javier Pérez-Areales retweeted
Hybrid Androgen Receptor Inhibitors Outperform Enzalutamide and EPI-001 in in vitro Models of Prostate Cancer Drug Resistance (Asim, Spring) @RaduNicolescu4; @SpringGroupChem; @dr_illo #openaccess onlinelibrary.wiley.com/doi/…
F. Javier Pérez-Areales retweeted
We're delighted to share our most recent work in antibody conjugation, featuring all-in-one disulfide bridging using TetraDVP reagents. Now in @ChemicalScience, check it out! doi.org/10.1039/d2sc02198f
@ChemCambridge
F. Javier Pérez-Areales retweeted
Unveiling the Multitarget Anti-Alzheimer Drug Discovery Landscape: A Bibliometric Analysis mdpi.com/1608816 #mdpipharmaceuticals a través de @MDPIOpenAccess
F. Javier Pérez-Areales retweeted
David Spring at @ChemCambridge, Jason Carroll at @CRUK_CI and colleagues use divinylpyrimidine reagents for the synthesis of antibody–drug conjugates.
@springgroupchem
rsc.li/3sR6Tr4
Congratulations to the team after such a long way and hard work!!
Grande Maufi @dlozanme!!! 👏🏻👏🏻👏🏻✌🏻
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🌔
ALL OVER THE MOON! 🤩
Our paper for the synthesis of Mechanically Planar Chiral Rotaxanes is out online in @NatureChemistry
#chemtwitter #chemistry
nature.com/articles/s41557-0…
Thank you so much @SpringGroupChem!! Particularly Morgan (aka Beth) and @RaduNicolescu4 for these kind gifts! 😊
F. Javier Pérez-Areales retweeted
Very excited to present our novel total syntheses of hemiasterlin and taltobulin and their first use as ADC payloads! onlinelibrary.wiley.com/doi/…
@StephenWalsh4 @angew_chem @CRUK_CI
F. Javier Pérez-Areales retweeted
Turning an antioxidant chroman derivative used in dermocosmetics into brain permeable multitarget anti-Alzheimer leads:
pubs.acs.org/doi/10.1021/acs…
So happy to announce the last piece of research from my PhD has been finally published in @JMedChem 😄😄😄 Thank you @DMunozTorrero and all our collaborators for your excellent work!! 👌🏻
pubs.acs.org/doi/10.1021/acs…
F. Javier Pérez-Areales retweeted
Fuelled by the shot of energy by our paper doi.org/10.1021/acs.jmedchem… just accepted in @JMedChem 👏🏻👏🏻👏🏻💪🏻💪🏻💪🏻
F. Javier Pérez-Areales retweeted
At this point, you’ve probably heard a ton about chloroquine and hydroxychloroquine and how they may be effective in treating COVID-19. I wanted to tell you about a different molecule that’s getting less attention but may have good potential – Remdesivir.
F. Javier Pérez-Areales retweeted
Please RT: Postdoc position available immediately in my group to investigate the structure, mechanism and druggability of new E3 ubiquitin ligases using structural cell biology. @UoDLifeSciences @DundeeUniJobs @mrcppu jobs.dundee.ac.uk/fe/tpl_uod…