All things Engineering and Biology, mostly Sober.

Bengaluru, India
Joined December 2016
RAJASTHAN SHOCKER A Heart-wrenching Incident happened at Narayan Multi-speciality Hospital, Jaipur. – A 19 yr old boy was brutally beaten in Police Premises & then taken to this Hospital. – There, he was given 10 Anti-Venom Injections. – Hospital generated a Hefty Bill of 96,000/- – Postmortem Report Clearly states that there was NO SNAKE BITE but A Head Injury. – When the journalist asked about the injection, everyone tried to hide their faces and demanded that the cameras be turned off; no one provided any answer. – Serious Concern : If there were no marks of a snakebite, why were anti-venom injections administered? Will the police investigate this? Who is responsible? Will the Family of the deceased get Justice ?
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Satish Gaurav retweeted
मैं आज बालाघाट आ रहा हूं। उन आदिवासी परिवारों से मिलने, जिन्होंने बीमारी और BJP सरकार की उपेक्षा के कारण अपने मासूम बच्चों को खोया है। उनके साथ वक्त बिताकर उन्हें बताना चाहता हूं कि इस दुख में वो अकेले नहीं हैं - मैं उनके साथ हूं। कुछ दिनों पहले केन-बेतवा आंदोलन के आदिवासी भाई-बहनों से भी मिला था। परियोजना के कारण आज उनके गांव डूब रहे हैं, मगर सरकार से उन्हें न पुनर्वास मिला न मुआवज़ा - मिला है तो प्रताड़ना, सरकारी दमन और हिंसा। इंदौर में ‘छात्रों की गूँज’ के दौरान भी आदिवासी छात्रों ने बताया - स्कूल नहीं हैं, कॉलेज बदहाल हैं, हॉस्टल और खाना नर्क जैसा, परीक्षाओं में धांधली और उनके आरक्षण के अधिकार से खिलवाड़ हो रहा है। मध्यप्रदेश के आदिवासियों की ये तकलीफें BJP-RSS की उस सोच का हिस्सा हैं जो उन्हें भारत के पहले मालिक नहीं, वनवासी मानती है। जल, जंगल, जमीन के साथ शिक्षा, रोजगार और सम्मान भी छीन लेना चाहती है और अहंकार में वो कुछ सुनना नहीं चाहती। आदिवासी भाई-बहनों को आश्वस्त करता हूं कि मैं आपके साथ हर संघर्ष में खड़ा हूं - आपकी आवाज़ बुलंद करना मेरी ज़िम्मेदारी है और मैं इस बहरी सरकार को वो पूरी शक्ति के साथ सुनाऊंगा।
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Satish Gaurav retweeted
ʙɪɴᴅᴄʀᴀꜰᴛ2 is out, and we're not waiting for the paper. The full code drops today, free for academic and industry use. We're releasing it early so you can start designing right now, and bring its full power to the current Adaptyv competition. github.com/PacesaLab/BindCra…
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ColabFold 1.6.3 is out! 2.5x faster, pip-installable, ipSAE+pDockQ2 scores. Thanks Choonghwan Lee, Marielle Russo, Gyuri Kim, Martin Steinegger, Milot Mirdita 🐍 pip install colabfold[alphafold] (1/3)
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Satish Gaurav retweeted
Escalante has one of the best technical blogs in AIxBio. They gained some notoriety after winning the @adaptyvbio protein design competition, but protein design is just the tip of the iceberg. In this latest blog they discuss a bit more about the assay they’ve designed to measure biophysics at scale.
We got really good at DNA sequencing a long time ago. Ever since, any problem that can be turned into a sequencing problem can be magically solved, giving rise to *-seq methods that form the backbone of modern genomics. This team at Escalante has done this for protein binding kinetics. A million interactions in one tube, one overnight reaction, one sequencing run. Worth the read... blog.escalante.bio/how-to-se…
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Satish Gaurav retweeted
At a time where Governments of the world should be coming together and work towards Climate Change, some are busy in conducting catastrophic wars, some in hoarding minerals, some in manufacturing migrant crisis, and others in marginalising minorities. None of them are representing human beings.
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Satish Gaurav retweeted
The accusation that I am antisemitic is appalling and fundamentally dishonest. Criticizing the actions of the Israeli prime minister, a military technology contract, or the executives who supply it is not the same as criticizing Jewish people. This critical and necessary dialogue is then dishonestly framed as being anti-Israel. To be clear, my views come from my own political convictions and should never be interpreted as hostility toward Jewish people, for whom I have deep love and respect.  Everything I know about acting, activism, and humanism has been profoundly shaped by the Jewish friends, colleagues, and loved ones who have been integral and family throughout every point of my life. This merger has real consequences for real people, and for the entire country. Scrutinizing the Ellisons, including Oracle’s business built on data, surveillance technology and government contracts, and the serious threat to editorial freedom and the loss of a livelihood for thousands of families, is fair and necessary. The $111 billion deal would hand one family control over CNN, HBO and Warner Bros., backed in part by foreign money whose influence on editorial decisions has never been fully explained to the public.  Lawmakers on both sides of the aisle have called for serious national security review, and regulators still haven’t given the public a real answer. Until they do, the merger shouldn’t move forward. Now is the time to dive boldly into all these issues, not step back or concede.
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Satish Gaurav retweeted
Zionistanis trigger such moral disgust.
Here's Israeli ghouls mocking Palestinians for having no access to clean water
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Satish Gaurav retweeted
Looks like claude-protein-binder-design rediscovered our Protein Hunter protocol? 🤔@ChoYehlin
Replying to @ChoYehlin
Protein Hunter: Starting from an all "X" sequence, we find that diffusion-based structure prediction models can hallucinate reasonable looking structures, which can be further improved through iterative sequence design and structure prediction, similar to AF2Cycler and LASErMPNN.
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Satish Gaurav retweeted
Vicious, mass criminals. An evil "state".
Israel killed all six members of the Hassan family, a mother, father and their four children, in their home in Ansar, southern Lebanon, today, during a supposed ceasefire.
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Waiting for the agent to escape the sandbox and come back with few newly designed enzymes! 😄
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Interesting development happening at Google and DeepMind.
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Satish Gaurav retweeted
The danger of selling to big companies, if you're a startup, is that they don't say no outright. They have months of meetings with you first. Since you hate meetings, that seems to you a sign of commitment. But it's not. They love having meetings! It's almost all they do.
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Satish Gaurav retweeted
Borneo’s orangutans, Assam’s elephants — wildlife across the world is fighting a losing battle against bulldozers, greed, and habitat destruction. They may fall, but their struggle will remain a painful reminder of humanity’s cruelty towards the planet.
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Satish Gaurav retweeted
Survival without self respect isn’t a victory, I’ll get a job that I can do standing up instead of performing stand up on my knees.
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Satish Gaurav retweeted
A bit of news: After nearly 9 years, I have decided to leave Google DeepMind and join Anthropic (after taking some time to recharge). I am incredibly grateful for my time at GDM. @demishassabis took a real chance letting me lead the AlphaFold team just six months after finishing my PhD, and the entire GDM team taught me so much about how to do great science. GDM is a special place, and I’ll still be excited to hear about what amazing things they discover next.
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Satish Gaurav retweeted
🍹Weekend project: I (with help from claude - budget $40), was able to get OpenFold3 weights running inside AlphaFold3 codebase (jax). Works for proteins, ligands, rna/dna (1/3)!
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Satish Gaurav retweeted
I visited the southernmost tip of India. I stood at Indira Point. I walked under trees that have stood for centuries. I dove into coral reefs among the most vibrant on earth. And I sat with the people who live there. Tribal communities, whose land is being taken away by violating the Forest Rights Act. Settlers, many of them former soldiers, placed on these islands by the Indian government, who aren’t getting fair compensation. The Modi government and BJP tells you Great Nicobar Project is about defence. It is not. Expand INS Baaz - we will back the government fully. The Navy has been asking for expansion for five years - it has been ignored. They tell you it is about a transhipment port. It is not. India is already building one in Kerala, which is on the mainland. What it actually is: 1.5 crore trees felled. Coral reefs erased from official maps. Soldiers and tribals displaced - so one businessman can build hotels and casinos on India’s most irreplaceable ecological land. Every young Indian I have spoken to understands this. You know that no amount of profit is worth destroying what can never be recovered. I stand for ecologically balanced development. These islands can be the most extraordinary sustainable destination the world has ever seen. That is the India worth fighting for. #GreenOverGreed #NicobarMatters #WorldEnvironmentDay
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Satish Gaurav retweeted
A Muslim woman was tied up and tortured to death during Ramzan in the house of her assailants. It was captured on camera. Only one arrested, and released on bail. Is this anything other than a de facto Apartheid state?
The only accused arrested in the lynching of a Muslim woman in Madhubani, Bihar has now been granted bail by a district court, leaving no one behind bars in the case. The accused, reportedly a social media district coordinator of Janata Dal (United), was the sole arrest among 19 people named in the FIR. The incident took place over two months ago during Ramadan, when the victim was tied to a pole and brutally beaten by a mob while she was fasting. Her family says that when she asked for water, she was instead forced to drink a mixture of alcohol and urine. She later succumbed to her injuries. Despite the gravity of the allegations, the case has seen minimal action, raising serious questions about the role of @bihar_police and the state administration in Bihar. #JusticeForRoshanKhatoon
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