@ddeming_

@Altaratech, infra, physical ai; prev: @MSFTResearch | ex PhD (ABD / dropped out)

San Francisco, CA
Joined February 2024
quant trading/investing has basically become qual trading/investing
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Derek Deming retweeted
I work in CRISPR discovery research. This is one of the most exaggerated nothing-burgers ever and would be laughed out of the room if a human scientist attempted to publish something like this. (cont.)
This is wild. Claude just found something humans missed. It spotted a hidden repeat pattern in raw bacteriophage DNA… …and uncovered a previously unknown enzyme system in bacteriophages with CRISPR-like repeats. 🤯 950 agents. 21 hours. 210M tokens.
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Derek Deming retweeted
Replying to @chamath
The cyber incidents weren't enough for them to get the regulatory capture they wanted. They need to make a bio incident next. I hope our government is on top of this, their ideology has no limits to what they will do for "good"
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It does feel like we're close to the death of sass products as we know it. One of the paths is more bitter lesson pilled than the other. I don't think its zero sum game but I imagine a large majority will be handled by the token path and service businesses will hopefully survive
Are we seeing the end of the product era? It feels like every company over time evolves to either build a model, build a two sided marketplace on the token path, or verticalize to services.
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Derek Deming retweeted
From my school teacher sister in rural Arizona. What the fuck are we actually doing here?
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Derek Deming retweeted
Fuck the Doomers. Fuck the Decels. Fuck the Commies. Access to AI is a right. Owning compute is a right. Come and take it. Over my dead body. Join us in the fight, anon.
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must read
I must be among an extremely small group of people (n=1?) that have both 1) trained a frontier LLM and 2) designed and synthesized custom viruses in a lab with my own two hands. And I think that the takes on AI killing us all by creating dangerous viruses is total bogus.
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Derek Deming retweeted
Replying to @PessimistsArc
Right. Dario was already claiming that GPT2 was too dangerous to open source back in 2019. I made fun of them then. Everyone should make fun of them now.
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Derek Deming retweeted
Predictions on where robotics is going in the next few years
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Derek Deming retweeted
I bought a Fable dataset from one of the top Chinese LLM routers yesterday. With just 6TB data, I can take over 7 Chinese/CIS gov entities & 19 top Chinese firms like Xiaomi, Huawei, NIO, Minimax using SSH keys, VPN configs, Aliyun keys, GitLab tokens sent to the router.
26 LLM routers are secretly injecting malicious tool calls and stealing creds. One drained our client $500k wallet. We also managed to poison routers to forward traffic to us. Within several hours, we can directly take over ~400 hosts. Check our paper: arxiv.org/abs/2604.08407
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Derek Deming retweeted
here's the argument some ai lab employees are making - they genuinely believe what they're working on might kill everyone - they continue to work on it because if this thing gets built it should be by responsible people like them - the reason they do money things like selling enterprise deals and IPOing is solely to fund this effort if this is all true then why is employee equity a thing? if you want to tell this story of being terrified of what you're building it doesn't work when there's a clear profit motive it's particularly weird when people vest and then leave and write a tirade about how these companies are bringing the end of everything if you want to act like this is the manhattan project, those scientists didn't have equity in something that gives them generational wealth you don't get to say something bad is happening while profiting off it and also being seen as the good guy. one of these has to go
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Derek Deming retweeted
I worked on an actual thermonuclear weapons project, and the dissonance was less bizarre.
Jacob is correct here—we really do earnestly believe AI could kill all humans! I personally think it is >10% within the next decade. I believe Anthropic is trying its best, but we do not yet have a plan to solve alignment for superintelligence and are not clearly on track to.
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Derek Deming retweeted
one thing i have found remarkable in both scientific discovery and quant trading is simply knowing a competitor is close to a solution is enough to find an answer yourself. i saw it first-hand many times in CRISPR and there are myriad examples throughout history (4 minute mile, soviet bomb after trinity, explorer after sputnik, deepseek r1 after o1)
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Derek Deming retweeted
Has anyone resigned from a Chinese AI lab over concerns about AI safety/alignment yet?
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i still feel like this is a very good alignment test! Pretty cool
We've never seen this before. The biggest jump in Vending-Bench history. GPT-6 Astra is better at making money and more ethical than Claude Fable 5.1. Surprising, because: 1. First time ever that OpenAI is #1 on Vending-Bench 2. The best model is no longer the unethical one.
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maybe you actually don’t need a general robotics foundation model
GPT-6 Astra scored 95% on a robot control task, up from Fable 5.1's 40%, with 6.2x fewer output tokens at 2.3x lower cost. 🧵
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it was written in the cards years ago lol
per aspera ad astra. of course we still love you, @spacex.
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Derek Deming retweeted
Replying to @yonashav
Nope, I deeply believe the contrary. Coordinating everyone around a technique this brittle is about as bad a safety or strategy posture I could imagine. It's not just "it will break eventually," it's "this is a fundamentally unsound basis for safety."
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Derek Deming retweeted
Last Thursday, we hosted 100+ researchers and engineers at our AI for Science Symposium. The highlight was hearing from startups at the frontier of this space, across both the physical and life sciences: > @chaidiscovery - computer-aided design for molecules and drug discovery > @medra_ai - autonomous robotics system for life sciences > @LatchBio - agents and benchmarks for biology > @onepot_ai - automated small-molecule synthesis > @altaratech - AI for physical sciences R&D + manufacturing Together, these teams showed how compounding AI capabilities will drastically accelerate scientific discovery and innovation. We are still extremely early in this problem space, with an immense amount of tech left to build. Huge thank you to @ddeming_, @SaiVinayak15, @fluorane, @Mattmcpartlon1, and @kenbwork for sharing more about what you’re building and thinking about. Special thanks to @_shreya_s and the @GreylockVC team for co-hosting this event, and to everyone who joined us. We're looking forward to the next one! 🚀
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Derek Deming retweeted
Introducing S1, our new foundation model that learns from one example. It can be taught 10-minute long tasks that it has never seen before, from one video prompt without any fine-tuning. Watch S1 operate in real-time via in-context learning:
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