Dan YEOH retweeted
Dr @danyeoh & colleagues on CT imaging of invasive mold infections in immunocompromised children: nodules & halo sign most common but no one feature predicts causative pathogen ➡️ microbiological sampling remains essential
sciencedirect.com/science/ar…
@ABsteward #IDtwitter #IDxposts
Dan YEOH retweeted
Nice review from @danyeoh and @gabhaeusler highlighting >10% of children with AML develop fungal infections, and prophylaxis with novel therapies. Triazoles are the mainstay but newer agents have distinct advantages for children pubmed.ncbi.nlm.nih.gov/3911…
@MCRI_for_Kids @ANZPID #AMS
Dan YEOH retweeted
Just published! Large Australian cohort of #COVID19 affecting cancer patients. A big team effort… showing decreasing severity and all cause mortality over time. @NCICancer @victoriahall26 @BeaCereus @benwteh @NCAS_Aus @monicaslavin
doi.org/10.1016/j.lanwpc.202…
Pleased to share our work @NCICancer - largest 🇦🇺 #COVID-19 in #cancer pts cohort to date @LancetRH_WPac. From 2020-2022, severity ⬇️; omicron 🦠 a/c w/ ⬇️ odds of O2, age/male/no OP Rx ⬆️ odds of O2. Big thanks to all involved & PhD supervisors @benwteh @michyong2 @monicaslavin
Dan YEOH retweeted
With the current surge of severe #StrepA/GAS #infections in children worldwide, a timely article by @Infection_MCRI member Dr @JoshOsowicki published in @JIDJournal - this article definitely should be a contender for 'Title of the Year'! @MCRI_for_kids 👏academic.oup.com/jid/article…
Dan YEOH retweeted
#ECCMID2023 CONCERT trial for congenital CMV, most common inf. cause of hearing loss. Non-randomised small study but babies given 6 weeks of valgan did better than controls who had worse hearing - will be hard to recruit future placebo arms. @sung_valerie @gabhaeusler @NCICancer
Dan YEOH retweeted
Multicentre study of IFI in paediatric acute leukaemia. Prov/Prob IFI remains high in ALL reflecting challenges of prophylaxis in this population. Great study @danyeoh
@NCICancer @Infection_MCRI @telethonkids #ECCMID2023
Dan YEOH retweeted
Led by PhD candidate/ID physician @danyeoh, an opportunity to harness the collective experience in diagnosing invasive pulmonary aspergillosis in Australian children - Timely diagnosis is key to improving outcomes @brendanmcID @monicaslavin @gabhaeusler
link.springer.com/article/10…
Dan YEOH retweeted
3. The ground is shaking beneath our feet- huge changes post-pandemic in RSV seasonality
AND importantly susceptibility
at @JohnsHopkins essentially no children under 17 months of age with RSV neutralising antibody!
Dan YEOH retweeted
BREAKING: Very exciting news for our Hospital National Antimicrobial Prescribing Survey users. We have launched the Antifungal NAPS "deep dive" audit! Participate in the first national Antifungal NAPS audit and benchmark the quality of antifungal use in your patient population.
ALT Access the NAPS at www.naps.org.au
Dan YEOH retweeted
Timely study from @NIH by Drs Susan Moir, Clarisa Buckner, Lela Kardava & colleagues
“When the interval [between infection & booster] is too short, the response induced by the recent infection appears to prevent B cells from responding to the subsequent booster vaccine…”
.@profshanecrotty was right again
Recent SARS-CoV-2 infection abrogates antibody and B-cell responses to booster vaccination medrxiv.org/content/10.1101/…
Dan YEOH retweeted
Conventional wisdom is that previous infection with omicron subvariant BA.1 or BA.2 does notprotect against BA.5, but data from Portugal show considerable protection against BA.5 infection from previous BA.1 or BA.2 infection. nej.md/3pVDLxz
Dan YEOH retweeted
In the year after pandemic lockdowns, we saw an increased incidence of invasive pneumococcal disease in toddlers, higher than pre-pandemic levels because kids in the lockdown year remained susceptible after lockdown was lifted: @CDC_EIDjournal …1/2
👉 wwwnc.cdc.gov/eid/article/28…
Dan YEOH retweeted
This is intriguing!!
Mycoplasma pneumoniae beyond the #COVID19 pandemic: where is it? #IDtwitter #medtwitter #TwitteRx #MedEd thelancet.com/journals/lanmi…
Dan YEOH retweeted
Infectious Diseases Society of America Guidance on the Treatment of AmpC β-Lactamase–Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections
🆓 Freely Available
🔗 bit.ly/3nRPvA7
😐 Evusheld 60-fold ⬇️ in neutralisation vs BA.5
✅ Bebtelovimab retains neutralising activity vs BA.5 (not available outside US 🙁)
✅ Antivirals (remdesivir, molnupiravir, paxlovid) retain activity vs BA.5
❌ Other monoclonal a/bs still dead in the water
🆕⚡⚡@NEJM
Efficacy of Monoclonal Antibodies and Antiviral Drugs against Omicron BA.2.12.1, BA.4, and BA.5 Subvariants
Bebtelovimab, Evusheld, Paxlovid, Molnupiravir, Remdesivir, others #IDTwitter
nejm.org/doi/full/10.1056/NE…
Dan YEOH retweeted
As rated #2 by @danyeoh at @ASIDANZ #ASID22, fascinating paper in @NEJM examining the use of Wolbachia infected A aegypti mosquitoes to reduce transmission of #Dengue in Indonesia. bit.ly/3ylw0Vp #IDTwitter #MedTwitter
Dan YEOH retweeted
💉 Vancomycin + pip–tazo associated with ⬆️risk of creatinine-defined #AKI in critically ill: pseudotoxicity?? No changes in alternative kidney function biomarkers, nor downstream clinical outcomes associated with true AKI (dialysis/mortality).
#FOAMcc
📎 rdcu.be/cRLAi
Dan YEOH retweeted
Check out these eosinophils swarming a nematode
#MedTwitter
Dan YEOH retweeted
Super interesting!
🆕⚡@CIDJournal
Congenital Tuberculosis after In-vitro Fertilization: A Case for Tuberculosis Screening of Women Evaluated for Infertility #IDTwitter #MedEd #TwitteRx academic.oup.com/cid/advance…