Migrated to Bluesky: @cijilim.bsky.social
Madison, WI
Joined October 2018
- Tweets5.4K
- Following1.1K
- Followers1.4K
- Likes13.8K
Pinned Tweet
Our paper in Science is out! @Sour_Agrawal, @xiuhua_linwisc, @viveksusvirkar, and the rest of the team show human RPA is a telomerase processivity factor essential for telomere maintenance. This reshapes our thinking about telomerase regulation. science.org/doi/10.1126/scie…
Ci Ji Lim retweeted
This is an amazing department, and we have genuinely enjoyed every minute of being part of it!!
We're hiring! The Biochemistry Dept is looking for a professor at any level to join our creative community. Candidates in all biochemistry areas will be considered. Apply by Oct. 15: jobs.wisc.edu/jobs/assistant…
ALT Graphic advertising the position. Job number JR10012489.
Ci Ji Lim retweeted
We're hiring! The Biochemistry Dept is looking for a professor at any level to join our creative community. Candidates in all biochemistry areas will be considered. Apply by Oct. 15: jobs.wisc.edu/jobs/assistant…
ALT Graphic advertising the position. Job number JR10012489.
Ci Ji Lim retweeted
Join us on Aug. 4 for Bianca Chavez's PhD thesis defense! @_biancachavez's research in the @cijilim Lab examined how telomere loops help to protect telomeres from degradation. Learn more: ipib.wisc.edu/2026/07/28/ipi…
Ci Ji Lim retweeted
Thrilled to share our collab with @GraceHibshman and the Shipman lab! Type IX retron-Kva2 structure reveals phage detection via an HTH fold, not a primary sequence. We computationally designed triggers that program bacteria cell death, pointing toward designer antimicrobials.
Ci Ji Lim retweeted
New online! Structural mechanism of TOPBP1 activating the ATR–ATRIP replication checkpoint kinase dlvr.it/TTgKfs
Ci Ji Lim retweeted
For biologists using Claude Science, here is Motif, an AI-native molecular biology workbench plugin. Now, you don't need to leave Claude Science to view and operate on your sequences.
Motif gives the full power of Claude to your upstream mol bio workflows, such as asking Claude to: 1) fetch the genes in a target pathway and annotate them, 2) perform and view multiple sequence alignments using your preferred alignment tool, 3) design and label CRISPR-Cas guide sequences, and much more.
Motif was built as part of the "Built with Claude: Life Sciences" hackathon, and is an MIT-licensed, open source plugin.
Also, Claude made this demo video using HeyGen's Hyperframes and Elevenlabs TTS.
Ci Ji Lim retweeted
WebCalEM: a browser-based tool for routine and accurate pixel-size calibration in cryo-EM doi.org/10.1107/S2053230X260…
Ci Ji Lim retweeted
EMBO Workshop
Cellular and systems mechanisms of memory in health and disease
27 – 30 April 2027 | Singapore
meetings.embo.org/event/27-m…
(cover image taken by Francesca Teo, UROPS student from our lab!)
Ci Ji Lim retweeted
Tremendous structure by Guillermo's team. Congrats
Our latest work on retrons reveal a giant retron ring-shaped assembly is now out: biorxiv.org/content/10.6...
Excellent work by
@ArturoCarabias and nice collaboration with @rafapinilla92 group
see also related work by biorxiv.org/content/10.64898… biorxiv.org/content/10.648
Ci Ji Lim retweeted
(1/5) Excited to share our new paper published in Advanced Science! We combined genome editing, super-resolution microscopy, and single-molecule tracking to investigate the endogenous oncogenic fusion transcription factor EWS::FLI1 in Ewing sarcoma cells. advanced.onlinelibrary.wiley…
Ci Ji Lim retweeted
New paper from the #DasGuptaLab!
Using directed evolution, we discovered RNA enzymes (ribozymes) that catalyze RNA ligation with absolute specificity for RNA sequences terminating in a 3′-phosphate - a molecular signature of broken RNAs.
Wow!! Congratulations to Dahai and his team at @NTU_LKCMedicine
Research update: Distinct #RNA engagements define genome import (with the help of nsP2 #helicase) and replication elongation (of course by nsP4 #RNA #polymerase) in #alphaviruses #chikungunya
biorxiv.org/content/10.64898…
Kaitlyn continues to break barriers with her innovations for using LEA proteins to solve another major cryo-EM sample prep issue! This work should be of great interest to friends who are struggling with particle orientation bias. Another funtastic Lim X Grant collaboration!
1/5: Our latest preprint is out!
We show that LEA proteins can diversify particle orientations in cryo-EM, helping to overcome preferred orientation at the air-water interface (AWI).
biorxiv.org/content/10.64898…
with @cijilim and @GrantCryoEMLab
#CryoEM #LEAproteins
Ci Ji Lim retweeted
On a gruelling hunt for rare associated molecules in your #cryoEM particle stack and not sure where to look?
Discover practical tips and tricks in our new case study using #CryoSPARC v4.7.1 where we find and refine a low-population interaction partner!
guide.cryosparc.com/processi…
New work from Tahirov x Lim collaboration! @QixiangHe from my lab contributed the cryo-EM structures for this work. We are excited to help explain how anti-HSV drugs work and to guide their future development.
science.org/doi/10.1126/scia…
@unmc @UWBiochem
We also like to point out a similar work published at the same time by researchers at Gilead Sciences 🤝💪: nature.com/articles/s41564-0…
Ci Ji Lim retweeted
2. Finding a protein critical for telomere maintenance (RPA) @ScienceMagazine #AlphaFold
science.org/doi/10.1126/scie…
Ci Ji Lim retweeted
New findings from @cijilim in @UWBiochem identify a protein as essential to maintaining the end-caps on chromosomes — helping doctors around the world connect a genetic mutation to their patients' illnesses.
biochem.wisc.edu/2025/10/30/…
Ci Ji Lim retweeted
📢 We’re hiring! @StanfordUChem is now accepting applications for a Junior Faculty Position in Chemistry (open area), with the appointment set to begin on September 1, 2026.
Learn more and apply here: facultypositions.stanford.ed…
#FacultyJobs #AcademicJobs #Hiring